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  • © 2012

Designs for Clinical Trials

Perspectives on Current Issues

  • Each chapter will be written by an expert conducting research in the topic of that chapter.
  • This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, and the design of studies in which missing data is anticipated.
  • The chapters serve as a guidance for statisticians designing trials.

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Hardcover Book USD 169.99
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  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xiv
  2. Designs for Phase I Trials

    • Ying Kuen Cheung
    Pages 1-27
  3. Sequential Designs for Clinical Trials

    • KyungMann Kim
    Pages 57-79
  4. On Stopping a Randomized Clinical Trial for Futility

    • Jay Herson, Marc Buyse, Janet Turk Wittes
    Pages 109-137
  5. Targeted Clinical Trials

    • Stephen L. George, Xiaofei Wang
    Pages 157-177
  6. Back Matter

    Pages 199-204

About this book

This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.  Each chapter will be written by an expert conducting research in the topic of that chapter.  As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.

Reviews

From the reviews:

“‘Designs for Clinical Trials: Perspectives on Current Issues’ fills the gap between professional journals and school textbooks by addressing a few important, rapidly evolving statistical topics. The book is intended for statistical practitioners like clinical trialists who actively use statistics but do not follow the literature on recent biostatistical thinking.” (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 9 (2), February, 2013)

Editors and Affiliations

  • Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA

    David Harrington

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access