Nucleic Acid Structure

1. Front Matter

   Pages I-XII

   PDF

2. Introduction

   • Wilhelm Guschlbauer

   Pages 1-3

3. Methods and Techniques

   • Wilhelm Guschlbauer

   Pages 4-14

4. Chemistry and Enzymology of Nucleic Acids

   • Wilhelm Guschlbauer

   Pages 15-31

5. Structure and Function of DNA

   • Wilhelm Guschlbauer

   Pages 32-51

6. Physical Chemistry of DNA—The Problems of DNA Research

   • Wilhelm Guschlbauer

   Pages 52-69

7. Model Systems for Nucleic Acids

   • Wilhelm Guschlbauer

   Pages 70-98

8. Errors and Mutations

   • Wilhelm Guschlbauer

   Pages 99-104

9. The Structure of Ribonucleic Acids

   • Wilhelm Guschlbauer

   Pages 105-123

10. Nucleic Acid — Protein Interactions

    • Wilhelm Guschlbauer

    Pages 124-130

11. Back Matter

    Pages 131-146

    PDF

Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin­ istrative overwork and excessive teaching obligations, had asked me to do so. This was generally done with a pile of notes and a dozen slides, and I always regretted that no small, concise, specialized book on nucleic acid structure for students at the senior or beginning graduate level ex­ isted. Every year, the lecture notes became more and more voluminous, with some key reprints intermingled. Everything changed when, in the spring of 1973, I re­ ceived an invitation to teach such a course, under the UNESCO-OAS-Molecular Biology Program at the Universi­ dad de Chile in Santiago during October 1973. I had ac­ cepted rather enthusiastically, but soon discovered that it would be necessary to produce a photocopied syllabus for the students. This was the fi rst premanuscript of this book. For nonscientific reasons, the course was first canceled and then postponed until December 1973. Nearly a year later, the course, in slightly amended form, was presented at the Lemonossow-State University in Moscow.

• DNA
• Nucleotid
• Nukleinsäure
• Peptid
• Protein
• RNA
• chemistry
• enzymology
• isolation
• nuclear magnetic resonance
• nuclear magnetic resonance (NMR)
• optical activity
• radiation
• reactions
• synthesis

• Service de Biochimie, Centre d’Études Nucléaires de Saclay, Gif-sur-Yvette, France

  Wilhelm Guschlbauer

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