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Toward Anti-Adhesion Therapy for Microbial Diseases

  • Book
  • © 1996

Overview

Editors:
  1. Itzhak Kahane

    1. The Hebrew University — Hadassah Medical School, Jerusalem, Israel

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    You can also search for this editor in PubMed   Google Scholar

  2. Itzhak Ofek

    1. Tel Aviv University — Sackler Medical School, Tel Aviv, Israel

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 408)

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Table of contents (30 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Carbohydrate—Lectin Interactions in Infectious Disease

    • Nathan Sharon
    Pages 1-8

  3. Anti-Adhesion and Diagnostic Strategies for Oro-Intestinal Bacterial Pathogens

    • Nicklas Strömberg, Stefan Ahlfors, Thomas Borén, Per Bratt, Kristina Hallberg, Karl-Johan Hammarström et al.
    Pages 9-24

  4. The GALα1–4GAL-Binding Adhesin of Streptococcus Suis, A Gram-Positive Meningitis-Associated Bacterium

    • Sauli Haataja, Kaarina Tikkanen, Jukka Hytönen, Jukka Finne
    Pages 25-34

  5. Development of Anti-Adhesion Carbohydrate Drugs for Clinical Use

    • D. Zopf, P. Simon, R. Barthelson, Diana Cundell, I. Idanpaan-Heikkila, E. Tuomanen
    Pages 35-38

  6. Towards Anti- Pseudomonas Aeruginosa Adhesion Therapy

    • Nechama Gilboa-Garber
    Pages 39-50

  7. Inhibition of Bacterial Adhesion and Infections by Lectin Blocking

    • J. Beuth, B. Stoffel, G. Pulverer
    Pages 51-56

  8. Adhesion and Invasion of Escherichia Coli

    • T. A. Oelschlaeger, J. Morschhäuser, C. Meier, C. Schipper, J. Hacker
    Pages 57-62

  9. Nonfimbrial Adhesins of Escherichia Coli

    • Janina Goldhar
    Pages 63-72

  10. Fimbriae—Mediated Adherence Induces Cosal Inflammation and Bacterial Clearance

    • Hugh Connell, William Agace, Maria Hedlund, Per Klemm, Mark Shembri, Catharina Svanborg
    Pages 73-80

  11. Group A Streptococcal Adhesion

    • David L. Hasty, Harry S. Courtney
    Pages 81-94

  12. Adhesins Of Staphylococcus Aureus that Bind Lewisa Antigen

    • C. C. Blackwell, A. T. Saadi, S. D. Essery, M. W. Raza, A. A. Zorgani, O. R. Elahmer et al.
    Pages 95-105

  13. Alternative Inhibitors Of Mycoplasma Adherence

    • Itzhak Kahane, Abed Athamna, David Yogev, Mordechai R. Kramer
    Pages 107-111

  14. Studies on the Molecular Mechanisms of Meningococcal Interactions with Human Cells

    • Mumtaz Virji
    Pages 113-122

  15. Lipopolysaccharide’s Role in the Association of Salmonella Cells to the Mouse Intestine Studied By Ribosomal in Situ Hybridization

    • K. A. Krogfelt, T. R. Licht, S. Molin
    Pages 123-128

  16. Interactions of Bacterial Adhesins with the Extracellular Matrix

    • Åsa Ljungh, Torkel Wadström
    Pages 129-140

  17. Proteins F1 And F2 of Streptococcus Pyogenes

    • Emanuel Hanski, Joseph Jaffe, Vered Ozeri
    Pages 141-150

  18. Adhesion Molecules in Leukocyte Endothelial Interaction

    • Amos Etzioni
    Pages 151-157

  19. Multiple Stages of Virus-Receptor Interactions as Shown by Simian Virus 40

    • Leonard C. Norkin, Howard A. Anderson
    Pages 159-167

  20. The Effect of Respiratory Virus Infection on Expression of Cell Surface Antigens Associated with Binding of Potentially Pathogenic Bacteria

    • O. R. Elahmer, M. W. Raza, M. M. Ogilvie, C. C. Blackwell, D. M. Weir, R. A. Elton
    Pages 169-177
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Keywords

About this book

The emergence of pathogens resistant to conventional antimicrobial agents has forced us to intensify the efforts in search for new approaches to prevent infectious diseases. Such a direction was indicated in studies over the last two decades showing that adhesion of pathogens, primarily via glycoconjugate or protein receptors of the host tissue, is crucial for the infectious process. Moreover, it was found that infection can be prevented by blocking adhesion of the pathogen to mucosal surfaces of the host. The various aspects of interference with the process of microbial adhesion as a way of preventing diseases were the subject of the Bat-Sheva Seminar, "Towards Anti-Adhesion Therapy of Microbial Infectious Diseases," held in Zichron Yaakov, Israel, February 25 to March I, 1996. A major aim of the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel, which sponsors a series of seminars, ours among them, is to provide the necessary tools and settings for international forums and exposure of young scientists and promising students to the state of the art of the field. This goal has been achieved during the week's discussions, and its major aspects are presented in this compendium. The seminar's participants, as well as the readers of this book, thank the founder and Foundation for their support. This book includes the major themes of this rapidly growing area. However, by no means do we intend to cover every bit and piece in it. The book's first section deals with the lectin-sugar interactions and their inhibitors.

Editors and Affiliations

  • The Hebrew University — Hadassah Medical School, Jerusalem, Israel

    Itzhak Kahane

  • Tel Aviv University — Sackler Medical School, Tel Aviv, Israel

    Itzhak Ofek

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