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Cholesterol

Its Functions and Metabolism in Biology and Medicine

  • Book
  • © 1997

Overview

Editors:
  1. Robert Bittman

    1. Department of Chemistry and Biochemistry, Queens College of The City University of New York, Flushing, USA

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Part of the book series: Subcellular Biochemistry (SCBI, volume 28)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xxviii
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  2. Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway

    • Simon M. Jackson, Johan Ericsson, Peter A. Edwards
    Pages 1-21

  3. Coordinate Regulation of Cholesterol 7α-Hydroxylase and HMG-CoA Reductase in the Liver

    • Ingemar Björkhem, Erik Lund, Mats Rudling
    Pages 23-55

  4. Polyprenyl Diphosphate Synthases

    • Kyozo Ogura, Tanetoshi Koyama, Hiroshi Sagami
    Pages 57-87

  5. Antifungal Sterol Biosynthesis Inhibitors

    • De-an Guo, Anil T. Mangla, Wen Zhou, Monica Lopez, Zhonghua Jia, S. Derrek Nichols et al.
    Pages 89-116

  6. The Smith—Lemli—Opitz Syndrome: A Potentially Fatal Birth Defect Caused by a Block in the Last Enzymatic Step in Cholesterol Biosynthesis

    • G. S. Tint, Ashok K. Batta, Guorong Xu, Sarah Shefer, Akira Honda, Mira Irons et al.
    Pages 117-144

  7. Has Nature Designed the Cholesterol Side Chain for Optimal Interaction with Phospholipids?

    • Robert Bittman
    Pages 145-171

  8. Cholesterol and Myelin

    • G. Jackson Snipes, Ueli Suter
    Pages 173-204

  9. Regulation of Mitochondrial Cholesterol Metabolism

    • Federico Martínez, Jerome F. Strauss III
    Pages 205-234

  10. Lipoproteins and Cellular Cholesterol Homeostasis

    • William J. Johnson, Michael C. Phillips, George H. Rothblat
    Pages 235-276

  11. Cholesterol-Sphingomyelin Interactions in Cells—Effects on Lipid Metabolism

    • J. Peter Slotte
    Pages 277-293

  12. Mechanisms and (Patho)Physiological Significance of Biliary Cholesterol Secretion

    • Folkert Kuipers, Ronald P. J. Oude Elferink, Henkjan J. Verkade, Albert K. Groen
    Pages 295-318

  13. Cholesterol Deposition in Atherosclerotic Lesions

    • Howard S. Kruth
    Pages 319-362

  14. Cholesterol Metabolism and Tumor Cell Proliferation

    • Peter S. Coleman, Li-Chuan Chen, Laura Sepp-Lorenzino
    Pages 363-435

  15. Biological Implications of the Niemann-Pick C Mutation

    • Peter G. Pentchev, E. Joan Blanchette-Mackie, Laura Liscum
    Pages 437-451

  16. Sitosterolemia

    • Gerald Salen, Sarah Shefer, Lien Nguyen, Gene C. Ness, G. S. Tint, Ashok K. Batta
    Pages 453-476

  17. Cholesterol Cytochemistry in Cell Biology and Disease

    • Nicholas J. Severs
    Pages 477-505

  18. Approaches for the Design of Novel Anti-Atherogenic Compounds

    • Erik A. L. Biessen, Leo A. J. M. Sliedregt, Theo J. C. Van Berkel
    Pages 507-539

  19. Back Matter

    Pages 541-548
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Keywords

About this book

Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases of the nervous system. The book's comprehensive coverage also includes the pathological consequences and potential therapies for various disease states, and the development of new anti-atherogenic drugs.

Reviews

`An excellent and up-to-date overview...A useful volume for libraries, investigators, or graduate students.'
Inform, September 1998

Editors and Affiliations

  • Department of Chemistry and Biochemistry, Queens College of The City University of New York, Flushing, USA

    Robert Bittman

Bibliographic Information

  • Book Title: Cholesterol

  • Book Subtitle: Its Functions and Metabolism in Biology and Medicine

  • Editors: Robert Bittman

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-1-4615-5901-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1997

  • Hardcover ISBN: 978-0-306-45478-3Published: 31 March 1997

  • Softcover ISBN: 978-1-4613-7707-8Published: 25 September 2012

  • eBook ISBN: 978-1-4615-5901-6Published: 11 November 2013

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: XXVIII, 548

  • Topics: Biochemistry, general, Animal Anatomy / Morphology / Histology, Plant Sciences

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