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Apoptosis Genes

  • Book
  • © 1998

Overview

Editors:
  1. James W. Wilson

    1. Epithelial Biology Laboratory, CRC Section of Cell and Tumour Biology, Patterson Institute for Cancer Research, Manchester, UK

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  2. Catherine Booth

    1. Epithelial Biology Laboratory, CRC Section of Cell and Tumour Biology, Patterson Institute for Cancer Research, Manchester, UK

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    You can also search for this editor in PubMed   Google Scholar

  3. Christopher S. Potten

    1. Epithelial Biology Laboratory, CRC Section of Cell and Tumour Biology, Patterson Institute for Cancer Research, Manchester, UK

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introduction

    • J. W. Wilson, C. Booth, C. S. Potten
    Pages 1-4

  3. The role of p53 in apoptosis

    • Maureen Murphy, Arnold J. Levine
    Pages 5-35

  4. Mammalian bcl-2 family genes

    • Thomas Chittenden
    Pages 37-84

  5. Stress-responsive signal transduction: emerging concepts and biological significance

    • Usha Kasid, Simeng Suy
    Pages 85-117

  6. Control of Apoptosis Through Gene Regulation

    • Yue Eugene Chin, Xin-Yuan Fu
    Pages 119-142

  7. Adhesion and Apoptosis

    • Andrew P. Gilmore, Charles H. Streuli
    Pages 143-165

  8. Death signalling in C. elegans and activation mechanisms of caspases

    • Asako Sugimoto, Masayuki Miura
    Pages 167-203

  9. Apoptosis in Drosophila

    • John P. Wing, John R. Nambu
    Pages 205-241

  10. Viral genes that modulate apoptosis

    • J. Marie Hardwick, Gary Ketner, Rollie J. Clem
    Pages 243-279

  11. Therapeutic manipulation of apoptosis in cancer and neurological disease

    • Alastair Watson, Pedro Lowenstein
    Pages 281-303

  12. Back Matter

    Pages 305-310
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Keywords

About this book

Apoptosis, or programmed cell death, is a natural process by which damaged or unwanted cells are dismantled in an orderly and atraumatic fashion. It is of critical importance in development, homeostasis, and cell population control. Research over the last decade is now enabling scientists to comprehend how genes and the protein products interact to control apoptosis. This has led to the current position where researchers may be able to directly modify the action of key proteins through gene therapy and antisense oligonucleotides.
Apoptosis Genes presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, Apoptosis Genes deals specifically with the regulation of apoptosis. Given the increased interest in the role of apoptosis genes in disease processes, this work will be useful to researchers investigating cancer, autoimmune disease, viral infection, cardiovascular disease, neurodegenerative disorders, AIDS, osteoporosis, and aging.

Editors and Affiliations

  • Epithelial Biology Laboratory, CRC Section of Cell and Tumour Biology, Patterson Institute for Cancer Research, Manchester, UK

    James W. Wilson, Catherine Booth, Christopher S. Potten

Bibliographic Information

  • Book Title: Apoptosis Genes

  • Editors: James W. Wilson, Catherine Booth, Christopher S. Potten

  • DOI: https://doi.org/10.1007/978-1-4615-5287-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1998

  • Hardcover ISBN: 978-0-412-83860-6Published: 31 January 1999

  • Softcover ISBN: 978-1-4613-7412-1Published: 16 December 2012

  • eBook ISBN: 978-1-4615-5287-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 310

  • Topics: Biochemistry, general, Human Genetics, Pharmacy, Cancer Research

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