Cerebral Cortex

1. Front Matter

   Pages i-xxvii

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2. Cognitive Profiles of Normal Human Aging

   • Marilyn S. Albert, Mark B. Moss

   Pages 1-20

3. Age-Related Cognitive Decline in the Rhesus Monkey

   • Mark B. Moss, Ronald J. Killiany, James G. Herndon

   Pages 21-47

4. Normal Aging in the Cerebral Cortex of Primates

   • Alan Peters

   Pages 49-80

5. Age-Related Neuronal Loss in the Cerebral Cortex

   • Mark J. West

   Pages 81-88

6. Age-Related Cognitive Deficits and Neurotransmitters

   • Amy F. T. Arnsten

   Pages 89-110

7. Neurotransmitter Receptor Changes in the Hippocampus and Cerebral Cortex in Normal Aging

   • Douglas L. Rosene, Timothy J. Nicholson

   Pages 111-128

8. Trophic Factors in Experimental Models of Adult Central Nervous System Injury

   • Daniel A. Peterson, Fred H. Gage

   Pages 129-173

9. Cortical Neuropathology in Aging and Dementing Disorders

   • Patrick R. Hof, Constantin Bouras, John H. Morrison

   Pages 175-311

10. The Anatomy of Dementias

    • Gene J. Blatt, Thomas L. Kemper

    Pages 313-364

11. Age-Related Changes in Subcortical Nuclei that Project to the Cerebral Cortex

    • Thomas L. Kemper

    Pages 365-397

12. Ultrastructural Changes in Dementing Illnesses

    • Imaharu Nakano, Asao Hirano

    Pages 399-431

13. Locating Genetic Modifiers for Inherited Neurodegenerative Diseases

    • Lindsay A. Farrer

    Pages 433-459

14. Early Features of Alzheimer’s Disease

    • Marilyn S. Albert, Mark B. Moss

    Pages 461-474

15. Temporal Sequence of Alzheimer’s Disease-Related Pathology

    • Heiko Braak, Eva Braak

    Pages 475-512

16. Neuropathological Correlates of Dementia in Alzheimer’s Disease

    • Eliezer Masliah, David P. Salmon

    Pages 513-551

17. Multifocal Cortical Neurodegeneration in Alzheimer’s Disease

    • Brent A. Vogt, Alex Martin, Kent E. Vrana, John R. Absher, Leslie J. Vogt, Patrick R. Hof

    Pages 553-601

18. Molecular Pathology of Alzheimer’s Disease and Related Disorders

    • Stephen D. Ginsberg, M. Luise Schmidt, Peter B. Crino, James H. Eberwine, Virginia M.-Y. Lee, John Q. Trojanowski

    Pages 603-654

19. Glutamate Receptors and Excitotoxic Mechanisms in Alzheimer’s Disease

    • James W. Geddes

    Pages 655-679

20. Nerve Growth Factor Systems in Alzheimer’s Disease

    • E. J. Mufson, J. H. Kordower

    Pages 681-731

This volume of Cerebral Cortex is dedicated to Sir John Eccles, who was an active member of the advisory board for the series until his death in May 1997. His input as to what topics should be covered in future volumes of this series will be sorely missed. The present volume is concerned with neurodegenerative disorders and age­ related changes in the structure and function of the cerebral cortex, a topic that has attracted increasing interest as longevity and the number of aged individuals in the population increase. Although much of the research on the neurodegenerative effects of aging has been centered on Alzheimer's disease, most of the aging popu­ lation will not be afflicted by this disease. They will, however, be affected by the consequences of normal aging, so the first few chapters of this volume are con­ cerned with that topic. Chapter 1, by Marilyn S. Albert and Mark B. Moss, gives an account of the cognitive changes that accompany normal human aging. Chapter 2, by Mark B.

• Alzheimer
• Nervous System
• Parkinson
• anatomy
• attention
• cortex
• development
• forebrain
• neurons

• Boston University School of Medicine, Boston, USA

  Alan Peters

• Mount Sinai Medical Center, New York, USA

  John H. Morrison

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