Skip to main content
SpringerLink
Log in

Perspectives on Biologically Based Cancer Risk Assessment

  • Book
  • © 1999

Overview

Editors:
  1. Vincent James Cogliano

    1. United States Environmental Protection Agency, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. E. Georg Luebeck

    1. Fred Hutchinson Cancer Research Center, Seattle, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Giovanni A. Zapponi

    1. National Institute of Health, Rome, Italy

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato Challenges of Modern Society (NATS, volume 23)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Introduction

    • V. J. Cogliano, E. D. Kroese, G. A. Zapponi, L. Attias, I. Marcello
    Pages 1-20

  3. The Biological Basis of Cancer

    • V. J. Cogliano, A. Kappas, G. Voutsinas, G. A. Zapponi
    Pages 21-47

  4. Sources of Data for Cancer Risk Assessment

    • A. Kappas, V. J. Cogliano, K. Watanabe, G. A. Zapponi
    Pages 49-80

  5. Use of Biochemical and Molecular Biomarkers for Cancer Risk Assessment in Humans

    • J. J. Amaral-Mendes, E. Pluygers
    Pages 81-182

  6. The Multistage Model of Carcinogenesis: A Critical Review of its Use

    • V. J. Cogliano, E. G. Luebeck, G. A. Zapponi
    Pages 183-204

  7. Biologically Based Models of Carcinogenesis

    • E. G. Luebeck, K. Watanabe, C. Travis
    Pages 205-241

  8. Statistical Issues in the Application of Multistage and Biologically Based Models

    • W. Wosniok, C. Kitsos, K. Watanabe
    Pages 243-273

  9. Informative Case Studies

    • E. G. Luebeck, C. Travis, K. Watanabe
    Pages 275-308

  10. Conclusions and Recommendations

    • J. J. Amaral-Mendes, J. V. Cogliano, A. Kappas, C. Kitsos, E. D. Kroese, E. G. Luebeck et al.
    Pages 309-314

  11. Back Matter

    Pages 315-319
    Download chapter PDF
Back to top

Keywords

About this book

The first meeting of the NATO/CCMS Pilot Study "Dose-Response Analysis and Biologically-Based Risk assessment for Initiator and Promoter Carcinogens" was held in Rome, Italy, in the spring of 1991, and was followed by annual or bi-annual meetings held in Germany, Greece, Netherlands, Portugal, USA, up to the end of 1995; in large part supported by NATO/CCMS grants or fellowships, and organized by Pilot Study participants. The Pilot Study activity has been characterized by a higly collaborative atmosphere, which was essential for a deep and detailed analysis of a problem on which different points of view, methodological approaches and regulations exist in the various member countries. The Pilot Study was aimed at proposing a carcinogenic risk assessment procedure which is based on a detailed analysis of the relevant biological processes, and may also consent the verification of hypotheses. The specific form of theoretical and mathe­ matical models is identified by considering and using the whole set of objective data available. The multidisciplinary approach of the pilot study is reflected by the struc­ ture of this book. Each chapter is the result of the cooperation of several authors from to produce a comprehensive manual that includes different countries; its objective was both theoretical and practical information.

Editors and Affiliations

  • United States Environmental Protection Agency, USA

    Vincent James Cogliano

  • Fred Hutchinson Cancer Research Center, Seattle, USA

    E. Georg Luebeck

  • National Institute of Health, Rome, Italy

    Giovanni A. Zapponi

Bibliographic Information

  • Book Title: Perspectives on Biologically Based Cancer Risk Assessment

  • Editors: Vincent James Cogliano, E. Georg Luebeck, Giovanni A. Zapponi

  • Series Title: Nato Challenges of Modern Society

  • DOI: https://doi.org/10.1007/978-1-4615-4741-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1999

  • Hardcover ISBN: 978-0-306-46108-8Published: 31 July 1999

  • Softcover ISBN: 978-1-4613-7149-6Published: 25 September 2012

  • eBook ISBN: 978-1-4615-4741-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIII, 319

  • Topics: Environmental Management, Oncology, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation