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Pulmonary Immunotoxicology

  • Book
  • © 2000

Overview

Editors:
  1. Mitchell D. Cohen

    1. Department of Environmental Medicine, New York University School of Medicine, Tuxedo, USA

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  2. Judith T. Zelikoff

    1. Department of Environmental Medicine, New York University School of Medicine, Tuxedo, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Richard B. Schlesinger

    1. Department of Environmental Medicine, New York University School of Medicine, Tuxedo, USA

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiv
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  2. The Respiratory Tract

    1. Comparative Structure of the Respiratory Tract: Airway Architecture in Humans and Animals

      • Jack R. Harkema, Charles G. Plopper, Kent E. Pinkerton
      Pages 1-59

    2. Immunology of the Respiratory Tract

      • Robert W. Lange, Meryl H. Karol
      Pages 61-84

    3. Disposition of Inhaled Particles and Gases

      • Richard B. Schlesinger
      Pages 85-105

  3. Adverse Effects of Altered Pulmonary Immunity

    1. Hypersensitivity and Asthma

      • M. Ian Gilmour
      Pages 107-126

    2. Inflammation and Fibrosis

      • David J. P. Bassett, Deepak K. Bhalla
      Pages 127-151

    3. Pulmonary Autoimmunity and Inflammation

      • Thomas M. Jeitner, David Lawrence
      Pages 153-179

  4. Immunotoxicants

    1. Biological Agents

      • Robert L. Sherwood
      Pages 181-197

    2. Pesticides, Solvents, and Polycyclic Agents

      • Kathleen E. Rodgers
      Pages 199-211

    3. Beryllium

      • Gregory L. Finch
      Pages 213-239

    4. Arsenic, Cadmium, Chromium, and Nickel

      • Leigh Ann Burns-Naas
      Pages 241-265

    5. Other Metals: Aluminum, Copper, Manganese, Selenium, Vanadium, and Zinc

      • Mitchell D. Cohen
      Pages 267-299

    6. Ozone

      • Lisa K. Ryan
      Pages 301-336

    7. Sulfur and Nitrogen Oxides

      • Richard B. Schlesinger, Lung-Chi Chen, Judith T. Zelikoff
      Pages 337-352

    8. Asbestos and Silica

      • David B. Warheit
      Pages 353-367

    9. Woodsmoke, Kerosene Heater Emissions, and Diesel Exhaust

      • Judith T. Zelikoff
      Pages 369-386

    10. Tobacco Smoke

      • Donald E. Gardner
      Pages 387-409

  5. Risk Assessment

    1. Applying Pulmonary Immunotoxicity Data to Risk Assessment

      • MaryJane K. Selgrade
      Pages 411-432

    2. Biomarkers of Pulmonary Immunologic Responses

      • Andrea K. Hubbard
      Pages 433-454

  6. Back Matter

    Pages 455-465
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Keywords

About this book

Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level.
Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.

Editors and Affiliations

  • Department of Environmental Medicine, New York University School of Medicine, Tuxedo, USA

    Mitchell D. Cohen, Judith T. Zelikoff, Richard B. Schlesinger

Bibliographic Information

  • Book Title: Pulmonary Immunotoxicology

  • Editors: Mitchell D. Cohen, Judith T. Zelikoff, Richard B. Schlesinger

  • DOI: https://doi.org/10.1007/978-1-4615-4535-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2000

  • Hardcover ISBN: 978-0-7923-7843-3Published: 30 June 2000

  • Softcover ISBN: 978-1-4613-7046-8Published: 08 October 2012

  • eBook ISBN: 978-1-4615-4535-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 465

  • Topics: Pneumology/Respiratory System, Ecotoxicology, Public Health, Veterinary Medicine/Veterinary Science, Immunology

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