Genetic Engineering

1. Front Matter

   Pages i-xviii

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2. Post-Transcriptional Light Regulation of Nuclear-Encoded Genes

   • Marie E. Petracek, W. F. Thompson

   Pages 1-10

3. Novel Methods of Introducing Pest and Disease Resistance to Crop Plants

   • Jeremy Bruenn

   Pages 11-22

4. Targeted Gene Repair in Mammalian Cells Using Chimeric Oligonucleotides

   • Eric B. Kmiec, Sarah Ye, Lan Peng

   Pages 23-31

5. Exploring the Mechanism of Action of Insecticidal Proteins by Genetic Engineering Methods

   • Jeremy L. Jenkins, Donald H. Dean

   Pages 33-54

6. Enzyme Stabilization by Directed Evolution

   • Anne Gershenson, Frances H. Arnold

   Pages 55-76

7. ET-Cloning: Think Recombination First

   • Joep P. P. Muyrers, Youming Zhang, A. Francis Stewart

   Pages 77-98

8. Growth and Genetic Modification of Human β-Cells and β-Cell Precursors

   • Gillian M. Beattie, Alberto Hayek, Fred Levine

   Pages 99-120

9. Elucidation of Biosynthetic Pathways by Retrodictive/Predictive Comparison of Isotopomer Patterns Determined by NMR Spectroscopy

   • Wolfgang Eisenreich, Adelbert Bacher

   Pages 121-153

10. Are Gene Silencing Mutants Good Tools for Reliable Transgene Expression or Reliable Silencing of Endogenous Genes in Plants?

    • Philippe Mourrain, Christophe Béclin, Hervé Vaucheret

    Pages 155-170

11. Manipulating Plant Viral RNA Transcription Signals

    • Cynthia L. Hemenway, Steven A. Lommel

    Pages 171-195

12. Genetic Engineering Strategies for Hematologic Malignancies

    • Thomas J. Kipps

    Pages 197-207

13. Telomerase and Cancer

    • Murray O. Robinson

    Pages 209-222

14. Back Matter

    Pages 223-232

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This volume, as with the previous books in the series, presents state-of-the-art discussions in genetics and genetic engineering by focusing on plant science and technology, agriculture, cell biology, and medical research.

• cloning
• evolution
• gene expression
• genes
• genetic engineering
• genetics
• mutant
• recombination
• transgene expression

• Brookhaven National Laboratory, Upton, USA

  Jane K. Setlow

Jane K. Setlow, PhD. has championed the field of genetics for over 30 years, agreeing to edit Genetic Engineering: Principles & Methods since its inception in 1979. An internationally recognized scientist with numerous publications, Dr. Setlow is the former Chairperson of the NIH Recombinant DNA Molecule Advisory Committee (RAC). Her lab can found at Brookhaven National Laboratory, Upton, New York.

Policies and ethics