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New Developments in Lipid-Protein Interactions and Receptor Function

  • Book
  • © 1993

Overview

Editors:
  1. K. W. A. Wirtz

    1. University of Utrecht, Utrecht, The Netherlands

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  2. L. Packer

    1. University of California, Berkeley, USA

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  3. J. Å. Gustafsson

    1. Karolinska Institute, NOVUM, Huddinge, Sweden

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  4. A. E. Evangelopoulos

    1. The National Hellenic Research Foundation, Athens, Greece

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  5. J. P. Changeux

    1. Institut Pasteur, Paris, France

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Part of the book series: NATO Science Series A: (NSSA, volume 246)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Components of Signal Transduction

    1. Intracellular Ca2+ Stores: Why, Where and How?

      • Jacopo Meldolesi, Alberto Ciardo, Antonello Villa, Fabio Grohovaz
      Pages 1-6

    2. The Metabolic Fates and Cellular Functions of Myoinositol

      • Ian Batty, A. Nigel Carter, C. Peter Downes, Francisco Estevez, Daniel Sillence, Cyrus Vaziri
      Pages 7-19

    3. Activation Mechanisms of Phospholipase C Isozymes

      • Sue Goo Rhee
      Pages 21-28

    4. Tumor Necrosis Factor Cytotoxicity is Associated with Activation of Cellular Phospholipases

      • Dirk De Valck, Rudi Beyaert, Frans Van Roy, Walter Fiers
      Pages 29-37

    5. Relationship between Phospholipase C, Tyrosine-Kinases and Cytoskeleton in Thrombin-Stimulated Platelets

      • Christine Guinebault, Monique Plantavid, Bernard Payrastre, Pascal Grondin, Claire Racaud-Sultan, Gérard Mauco et al.
      Pages 39-44

    6. Lipid Modifications of GTP-Binding Regulatory Proteins

      • Patrick J. Casey
      Pages 45-54

  3. Receptor Function and Regulation

    1. Lysophosphatidic Acid as a Lipid Mediator: Signal Transduction and Receptor Identification

      • Wouter Moolenaar, Rob van der Bend, Emile van Corven, Kees Jalink, Thomas Eichholtz, Wim van Blitterswijk
      Pages 55-61

    2. The Role of Lipoprotein Receptors in the Growth of Chicken Oocytes

      • Wolfgang J. Schneider
      Pages 63-72

    3. Modulation of Opioid Receptor Function by Membrane Lipids

      • Fedor Medzihradsky
      Pages 73-86

    4. A Pharmacological Approach to Identify Hormone Signaling Pathways Controlling Gene Regulation in Dictyostelium

      • Ron D. M. Soede, Dorien J. M. Peters, Bernd Jastorff, Peter J. M. Van Haastert, Pauline Schaap
      Pages 87-101

    5. Glycosyl-Phosphatidylinositol: Role in Neurotrophic Factors Signalling

      • Matias A. Avila, Yolanda León, Beatriz Gil, Isabel Varela-Nieto
      Pages 103-113

    6. Pharmacological, Electrophysiological and Molecular Analysis of a Dopamine Receptor in a Specific Subset of Neurons in the Central Nervous System of the Pond Snail Lymnaea Stagnalis

      • Cindy C. Gerhardt, Hans J. Lodder, Ellen van Kesteren, Rudi J. Planta, Karel S. Kits, Harm van Heerikhuizen et al.
      Pages 115-128

  4. Transcription Factors and Gene Regulation

    1. Regulation of Gene Expression in Rodent Hepatocytes

      • Kleanthis G. Xanthopoulos
      Pages 129-137

    2. Transcription Factor Crem: A Key Element of the Nuclear Response to cAMP

      • Denis Masquilier, Brid M. Laoide, Véronique Delmas, Rolf P. de Groot, Nicholas S. Foulkes, Enrico Benusiglio et al.
      Pages 139-152

    3. Three-Dimensional Structure of the Human Retinoic Acid Receptor-β DNA Binding Domain: Implications for DNA-Binding

      • Ronald M. A. Knegtel, Masato Katahira, Johannes G. Schilthuis, Rolf Boelens, Douglas Eib, Paul T. van der Saag et al.
      Pages 153-168

    4. Molecular Genetics of Plasma Lipid Transfer Proteins

      • Alan Tall
      Pages 169-174

  5. Biosynthesis, Insertion and function of Membrane Components

    1. Targeting Signals and Mechanisms of Protein Insertion into Membranes

      • Gunnar von Heijne
      Pages 175-182

    2. Recognition of Precursor Proteins by the Mitochondrial Protein Import Apparatus

      • Karin Becker, Walter Neupert
      Pages 183-197

    3. A Short N-Terminal Domain of Mitochondrial Creatine Kinase is Involved in Octamer Formation but not in Membrane Binding

      • Philipp Kaldis, Hans M. Eppenberger, Theo Wallimann
      Pages 199-211
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Keywords

About this book

A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholipid transfer proteins. This book presents the content of the major lectures and a selection of the most relevant of the most important topics posters. These proceedings offer a comprehensive account presented during the course of the Institute. The book is intended to make these proceedings accessible to a large audience.

Editors and Affiliations

  • University of Utrecht, Utrecht, The Netherlands

    K. W. A. Wirtz

  • University of California, Berkeley, USA

    L. Packer

  • Karolinska Institute, NOVUM, Huddinge, Sweden

    J. Å. Gustafsson

  • The National Hellenic Research Foundation, Athens, Greece

    A. E. Evangelopoulos

  • Institut Pasteur, Paris, France

    J. P. Changeux

Bibliographic Information

  • Book Title: New Developments in Lipid-Protein Interactions and Receptor Function

  • Editors: K. W. A. Wirtz, L. Packer, J. Å. Gustafsson, A. E. Evangelopoulos, J. P. Changeux

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4615-2860-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1993

  • Hardcover ISBN: 978-0-306-44521-7Published: 30 September 1993

  • Softcover ISBN: 978-1-4613-6239-5Published: 24 October 2012

  • eBook ISBN: 978-1-4615-2860-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 318

  • Topics: Biochemistry, general, Human Genetics, Animal Anatomy / Morphology / Histology, Plant Sciences

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