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A Multidisciplinary Approach to Myelin Diseases II

  • Book
  • © 1994

Overview

Editors:
  1. S. Salvati

    1. Istituto Superiore di Sanità, Rome, Italy

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Part of the book series: NATO Science Series A: (NSSA, volume 258)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-ix
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  2. Myelin Genes and their Regulation

    1. The Proteolipid Protein Gene Family: Three New Members and Evidence for Their Common Origin from a Primitive Membrane Channel

      • K. Kitagawa, D. R. Colman
      Pages 1-9

    2. Transgenic Models for Investigating Oligodendrocyte Differentiation and Myelin Formation

      • Wendy B. Macklin, Patricia A. Wight, Cynthia S. Duchala, Carol Readhead
      Pages 11-22

    3. Axonal Contact Induces Oligodendroglial Specific Transcription of the MBP Gene from the Proximal Promoter Region

      • C. Goujet-Zalc, C. Lubetzki, Ch. Babinet, M. Monge, S. Timsit, C. Demerens et al.
      Pages 23-28

    4. Retrovirus-Mediated Gene Transfer of PMP22 in Schwann Cells: Studies on Cell Growth

      • Georg Zoidl, Corinne Schmalenbach, Hans Werner Müller
      Pages 29-36

  3. Myelin Assembly

    1. Protein Sorting and Targeting in Myelin-Forming Schwann Cells

      • Bruce D. Trapp, Grahame Kidd, S. Brian Andrews
      Pages 37-48

    2. Cellular and Molecular Characteristics of CNP Suggest Regulatory Mechanisms in Myelinogenesis

      • Dino De Angelis, Martha Cox, Enoch Gao, Peter E. Braun
      Pages 49-58

    3. Myelin Basic Protein mRNA Translocation in Oligodendrocytes Involves Microtubules and is Inhibited by Astrocytes in Vitro

      • Shashi Amur-Umarjee, Anthony T. Campagnoni
      Pages 59-69

    4. The Cytoskeleton in the Differentiation of Myelin-Forming Cells

      • Peter J. Brophy, C. Stewart Gillespie, Bernadette M. Kelly, Demetrius A. Vouyiouklis
      Pages 71-82

    5. Regulation of Brain Stearoyl CoA Desaturase mRNA Expression During Myelination

      • James DeWille
      Pages 83-92

    6. Dietary Lipids: Exogenous Control of Myelination

      • Serafina Salvati, Lucilla Attorri, Cristina Avellino, Antonella Di Biase, Annamaria Confaloni
      Pages 93-101

  4. Experimental Models to Study Demyelinating Diseases

    1. MOCH-1 Cells: An Oligodendrocyte Cell Line Generated Using a Transgenic Approach

      • Brian Popko, Carol Hayes, Yan Li, Donna Kelly, Shigeo Murayama, Kinuko Suzuki
      Pages 103-113

    2. Molecular Biology and Neurogenetics of Myelin Proteolipid Protein

      • Klaus-Armin Nave, Armin Schneider, Carol Readhead, Ian Griffiths, Anja Pühlhofer, Angelika Bartholomä et al.
      Pages 115-126

    3. Measles Virus Induced Autoimmune Reactions against Brain Antigen

      • Uwe G. Liebert, Volker ter Meulen
      Pages 127-135

    4. Mechanisms of DE — and Remyelination in Autoimmune Encephalomyelitis and Multiple Sclerosis

      • Hans Lassmann, Gerda Suchanek, Mascha Schmied
      Pages 137-141
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Keywords

About this book

The diseases that fall under the generalized group of demyelinating diseases -Multiple Sclerosis, Leukodystrophyes, Encephalomyelitis-are the focus of worldwide concern. This volume contains papers presented by leading scientists who attended the NATO Advanced Research Workshop held at the Istituto Superiore di SanitA, Rome, March 1-4, 1993. This book is an update of the previous one published in 1987 of the research discussed at a similar meeting held in 1986. It was decided to hold this 2nd meeting since there has been great progress in the advances in understanding the myelinogenesis process in the last five years. The workshop gathered together scientists from many fields such as cellular and molecular biology, immunology, pathology, virology and of course clinical neurology. Stimulating ideas were exchanged in the hope that more knowledge of demyelinating diseases can lead to new theraupetic approaches. Although the workshop was on the whole similar to the previous one, this time there was more emphasis on experimental models and clinical aspects. In the former the use of animal and cellular models as tools for understanding the pathological mechanisms linked to human disease were discussed; in the latter the clinicians described the filtering down of basic research to clinical treatment The publication of this interdisciplinary exchange is to make known the results of the most recent research among the investigators from allover the world involved in these studies.

Editors and Affiliations

  • Istituto Superiore di Sanità, Rome, Italy

    S. Salvati

Bibliographic Information

  • Book Title: A Multidisciplinary Approach to Myelin Diseases II

  • Editors: S. Salvati

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4615-2435-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1994

  • Hardcover ISBN: 978-0-306-44634-4Due: 31 March 1994

  • Softcover ISBN: 978-1-4613-6034-6Published: 27 December 2011

  • eBook ISBN: 978-1-4615-2435-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 274

  • Number of Illustrations: 62 b/w illustrations

  • Topics: Immunology, Animal Anatomy / Morphology / Histology, Plant Sciences, Neurosciences

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