Cardiac Energetics: From Emax to Pressure-Volume Area

1. Front Matter

   Pages i-xii

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2. Energy Costs of PVA and Emax:Constancy and Variability

   • Hiroyuki Suga, Miyako Takaki, Hiromi Matsubara, Yoichi Goto

   Pages 1-15

3. Kinetic Property of Cardiac Myosin In Vitro

   • Seiryo Sugiura, Hiroshi Yamashita, Masataka Sata, Hideo Fujita, Shin-ichi Momomura, Takashi Serizawa et al.

   Pages 17-27

4. Thin Filament Regulation and Cardiac Energetics

   • R. John Solaro

   Pages 29-40

5. Explaining Load-dependent Ventricular Performance and Energetics Based on a Model of E-C Coupling

   • Daniel Burkhoff, Matthew Schnellbacher, Richard A. Stennett, Donna Zwas, Kazuhide Ogino, James P. Morgan

   Pages 41-52

6. Cardiac Contractions, PVA and Energetic Considerations Determined from a Cardiac Muscle Crossbridge Model

   • Tad W. Taylor, Yoichi Goto, Hiroyuki Suga

   Pages 53-63

7. Normalization of Emax and PVA

   • Motoaki Sugawara, Yukiyoshi Kondoh, Kiyoharu Nakano

   Pages 65-78

8. Observations on the Relation of PVA and MVO2 in Closed Chest Dogs

   • Gregory L. Freeman, Sumanth D. Prabhu

   Pages 79-89

9. Regional Myocardial Contraction Coupled With Energetics

   • Yoichi Goto, Satoshi Yasuda, Toshiaki Shishido, Kengo Fukushima, Shogo Suzuki

   Pages 91-101

10. Energetics During Ventricular Fibrillation

    • Hideo Kusuoka, Eduardo Marban

    Pages 103-112

11. Influence of Preload on Non-Mechanical VO2 Assessed with 2,3-Butanedione Monoxime

    • Martin M. LeWinter, Akihiro Higashiyama, Hitoshi Yaku, Matthew W. Watkins

    Pages 113-127

12. Emax and Myocardial Microcirculation

    • Fumihiko Kajiya, Toyotaka Yada, Yasuo Ogasawara, Shigeru Ohta, Osamu Hiramatsu, Masami Goto et al.

    Pages 129-141

13. Efficiency of Ventricular-Arterial Coupling and Baroreflex Regulation of Blood Pressure

    • Kenji Sunagawa, Masaru Sugimachi, Yasuhiro Ikeda, Osamu Kawaguchi, Toshiaki Shishido, Toru Kawada

    Pages 143-155

14. Ventriculo-Arterial Load Matching of Failing Hearts

    • Hidetsugu Asanoi, Tomoki Kameyama, Shinju Ishizaka

    Pages 157-169

15. Calcium Signaling and Pharmacology of Cardiotonic Agents

    • Masao Endoh

    Pages 171-199

16. Effect of Inotropic Agents on Mechanoenergetics in Human Diseased Heart

    • Motoshi Takeuchi, Hideyuki Takaoka, Katsuya Hata, Masuki Mori, Hideyuki Yamakawa, Mitsuhiro Yokoyama

    Pages 201-212

17. Effects of Various Inotropic Agents on the Relation Between Ventriculoarterial Coupling and Myocardial Energetics in Patients with Idiopathic Dilated Cardiomyopathy

    • Mitsuhiro Yokota, Hitoshi Ishihara, Toshikazu Sobue

    Pages 213-227

18. Back Matter

    Pages 229-240

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Most of the progress in cardiac energetics in recent years has been spurred by the pressure-volume area concept, the natural extension into energetics of earlier pioneering work delineating the time-varying elastance framework for ventricular contraction. The book draws together a broad spectrum of researchers - basic, applied and clinical - having a shared interest in the energetics of cardiac muscle and ventricle, providing an overview of the current state of the art.

• artery
• blood
• calcium
• circulation
• efficiency
• energy
• muscle
• patients
• pharmacology
• regulation
• research

• Cardiology Unit, Department of Medicine, University of Vermont, Burlington, USA

  Martin M. LeWinter, Matthew W. Watkins

• Department of Physiology II, Okayama University Medical School, Okayama 700, Japan

  Hiroyuki Suga

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