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Corona- and Related Viruses

Current Concepts in Molecular Biology and Pathogenesis

  • Book
  • © 1995

Overview

Editors:
  1. Pierre J. Talbot

    1. Armand-Frappier Institute, University of Québec, Laval, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Gary A. Levy

    1. The Toronto Hospital, University of Toronto, Toronto, Canada

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 380)

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Table of contents (94 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Pathogenesis

    1. Front Matter

      Pages N1-N1
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    2. Genetic Resistance to Coronavirus Infection

      • Ellen Buschman, Emil Skamene
      Pages 1-11

    3. Factors Controlling Coronavirus Infections and Disease of the Central Nervous System

      • S. Dales
      Pages 13-22

    4. Characterization of the S Protein of Enterotropic Murine Coronavirus Strain-Y

      • Susan R. Compton, Satoshi Kunita
      Pages 23-28

    5. Biological and Molecular Differentiation Between Coronaviruses Associated with Neonatal Calf Diarrhoea and Winter Dysentery in Adult Cattle

      • G. Millane, L. Michaud, S. Dea
      Pages 29-33

    6. Molecular Differentiation of Transmissible Gastroenteritis Virus and Porcine Respiratory Coronavirus Strains

      • D. J. Jackwood, H. M. Kwon, L. J. Saif
      Pages 35-41

    7. Organ Specific Endothelial Cell Heterogeneity Influences Differential Replication and Cytopathogenicity of MHV-3 and MHV-4

      • J. Joseph, R. Kim, K. Siebert, F. D. Lublin, C. Offenbach, R. L. Knobler
      Pages 43-50

    8. Genomic Regions Associated with Neurotropism Identified in MHV by RNA-RNA Recombination

      • Ehud Lavi, Qian Wang, Susan T. Hingley, Susan R. Weiss
      Pages 51-56

    9. Involvement of Microtubules and the Microtubule-Associated Protein TAU in Trafficking of JHM Virus and Components within Neurons

      • Kishna Kalicharran, Samuel Dales
      Pages 57-61

    10. Evolution and Persistence Mechanisms of Mouse Hepatitis Virus

      • Wan Chen, Ralph S. Baric
      Pages 63-71

    11. Spread of MHV-JHM from Nasal Cavity to White Matter of Spinal Cord

      • S. Perlman, N. Sun, E. M. Barnett
      Pages 73-78

    12. In Vitro Interaction of Coronaviruses with Primate and Human Brain Microvascular Endothelial Cells

      • G. F. Cabirac, R. S. Murray, L. B. McLaughlin, D. M. Skolnick, B. Hogue, K. Dorovini-Zis et al.
      Pages 79-88

    13. Treatment of Resistant A/J Mice with Methylprednisolone (MP) Results in Loss of Resistance to Murine Hepatitis Strain 3 (MHV-3) and Induction of Macrophage Procoagulant Activity (PCA)

      • R. J. Fingerote, J. L. Leibowitz, Y. S. Rao, G. A. Levy
      Pages 89-94

    14. Ultrastructural Characteristics and Morphogenesis of Porcine Reproductive and Respiratory Syndrome Virus Propagated in the Highly Permissive MARC-145 Cell Clone

      • S. Dea, N. Sawyer, R. Alain, R. Athanassious
      Pages 95-98

    15. Antigenic and Genomic Variations Among Cytopathic and Non-Cytopathic Strains of Bovine Enteric Coronavirus

      • S. Dea, L. Michaud, R. Rekik
      Pages 99-101

    16. Fragmentation and Rearrangement of the Golgi Apparatus During MHV Infection of L-2 Cells

      • Ehud Lavi, Qian Wang, Anna Stieber, Youjun Chen, Susan Weiss, Nicholas K. Gonatas
      Pages 103-104

    17. Severe Combined Immunodeficiency (SCID) Mouse Hepatitis Experimentally Induced with Low Virulence Mouse Hepatitis Virus

      • Koji Uetsuka, Hiroyuki Nakayama, Naoaki Goto, Kosaku Fujiwara
      Pages 105-107

    18. Mouse Hepatitis Virus-Specific CD8+ Cytotoxic T Lymphocytes Induce Apoptosis in Their Target Cells

      • Shinwa Shibata, Shigeru Kyuwa, Kosaku Fujiwara, Yutaka Toyoda, Naoaki Goto
      Pages 109-111

    19. Echocardiographic Changes Following Rabbit Coronavirus Infection

      • Lorraine K. Alexander, Bruce W. Keene, Ralph S. Baric
      Pages 113-115
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Keywords

About this book

Corona- and related viruses are important human and animal pathogens that also serve as models for other viral-mediated diseases. Interest in these pathogens has grown tremendously since the First International Symposium was held at the Institute of Virology and Immunobiology of the University of Wiirzburg, Germany. The Sixth International Symposium was held in Quebec City from August 27 to September I, 1994, and provided further understanding of the molecular biology, immunology, and pathogenesis of corona-, toro-, and arterivirus infections. Lectures were given on the molecular biology, pathogenesis, immune responses, and development of vaccines. Studies on the pathogenesis of coronavirus infections have been focused mainly on murine coronavirus, and mouse hepatitis virus. Neurotropic strains ofMHV (e.g., JHM, A59) cause a demyelinating disease that has served as an animal model for human multiple sclerosis. Dr. Samuel Dales, of the University of Western Ontario, London, Canada, gavea state-of-the-art lecture on our current under­ standing of the pathogenesis of JHM-induced disease.

Editors and Affiliations

  • Armand-Frappier Institute, University of Québec, Laval, Canada

    Pierre J. Talbot

  • The Toronto Hospital, University of Toronto, Toronto, Canada

    Gary A. Levy

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