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Biological Reactive Intermediates Vi

Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases

  • Book
  • © 2001

Overview

Editors:
  1. Patrick M. Dansette

    1. Université René Descartes, Paris, France

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  2. Robert Snyder

    1. Rutgers University and The Environmental & Occupational Health Sciences Institute, Piscataway, USA

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  3. Marcel Delaforge

    1. CNRS, Paris, France

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  4. G. Gordon Gibson

    1. University of Surrey, Guildford, Surrey, England

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  5. Helmut Greim

    1. Institute of Toxicology and Environmental Health, The Technical University of Munich, Munich, Germany

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  6. David J. Jollow

    1. Medical University of South Carolina, Charleston, USA

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  7. Terrence J. Monks

    1. University of Texas, Austin, USA

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  8. I. Glenn Sipes

    1. University of Arizona, Tucson, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 500)

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Table of contents (104 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Biological Reactive Intermediates and Mechanisms of Cell Death

    • John D. Robertson, Joya Chandra, Vladimir Gogvadze, Sten Orrenius
    Pages 1-10

  3. Structure Activity Relationships for the Chemical Behaviour and Toxicity of Electrophilic Quinones/Quinone Methides

    • Ivonne M. C. M. Rietjens, Hanem M. Awad, Marelle G. Boersma, Marlou L. P. S. van Iersel, Jacques Vervoort, Peter J. van Bladeren
    Pages 11-21

  4. Use of Structure-Activity Relationships for Probing Biochemical Mechanisms: Glutathione Transferase Zeta Conjugation of Haloacids

    • Paul D. Swartz, Ann M. Richard
    Pages 23-31

  5. Structure Toxicity Relationships - How Useful Are They in Predicting Toxicities of New Drugs?

    • Sidney D. Nelson
    Pages 33-43

  6. Biological Reactive Intermediates in Drug Discovery and Development

    • Thomas A. Baillie, Kelem Kassahun
    Pages 45-51

  7. Bioactivation of Toxicants by Cytochrome P450-Mediated Dehydrogenation Mechanisms

    • Garold S. Yost
    Pages 53-62

  8. New Aspects of DNA Adduct Formation by the Carcinogens Crotonaldehyde and Acetaldehyde

    • Stephen S. Hecht, Edward J. McIntee, Guang Cheng, Yongli Shi, Peter W. Villalta, Mingyao Wang
    Pages 63-71

  9. Mechanisms of Ovotoxicity Induced by Environmental Chemicals: 4-Vinylcyclohexene Diepoxide as a Model Chemical

    • Patricia B. Hoyer, Ellen A. Cannady, Nicole A. Kroeger, I. Glenn Sipes
    Pages 73-81

  10. Mutagenicity and Carcinogenicity of Biological Reactive Intermediate’s Derived from a “Non-Genotoxic” Carcinogen

    • Serrine S. Lau, Hae-Seong Yoon, Sonal K. Patel, Jeffrey I. Everitt, Cheryl L. Walker, Terrence J. Monks
    Pages 83-92

  11. Reactive Metabolites of 1,3-Butadiene: DNA and Hemoglobin Adduct Formation and Potential Roles in Carcinogenicity

    • Adnan A. Elfarra, Thomas S. Moll, Renee J. Krause, Raymond A. Kemper, Rebecca R. Selzer
    Pages 93-103

  12. Chemistry and Biological Activity of Novel Selenium-Containing Compounds

    • Jan N. M. Commandeur, Martijn Rooseboom, Nico P. E. Vermeulen
    Pages 105-112

  13. Formation and Fate of Reactive Intermediates of Haloalkanes, Haloalkenes, and α-Haloacids

    • M. W. Anders
    Pages 113-120

  14. Human Epoxide Hydrolase is the Target of Germander Autoantibodies on the Surface of Human Hepatocytes: Enzymatic Implications

    • Jacqueline Loeper, Veronique De Berardinis, Claude Moulis, Philippe Beaune, Dominique Pessayre, Denis Pompon
    Pages 121-124

  15. Structural Characterisation Of the Main Epichlorohydringuanosine Adducts

    • Jukka Mäki, Krister Karlsson, Rainer Sjöholm, Leif Kronberg
    Pages 125-128

  16. Adducts of the Chloroform Metabolite Phosgene

    • Laura Fabrizi, Graham W. Taylor, Robert J. Edwards, Alan R. Boobis
    Pages 129-132

  17. Oxygenation of Arachidonic Acid by Cyclooxygenases Generates Reactive Intermediates That Form Adducts with Proteins

    • Olivier Boutaud, Junyu Li, Pierre Chaurand, Cynthia J. Brame, Lawrence J. Marnett, L. Jackson Roberts et al.
    Pages 133-137

  18. Use of Isotopes and LC-MS-ESI-TOF for Mechanistic Studies of Tienilic Acid Metabolic Activation

    • Maya Belghazi, Pascale Jean, Sonia Poli, Jean-Marie Schmitter, Daniel Mansuy, M. Patrick Dansette
    Pages 139-144

  19. Inhibition by Ticlopidine and Its Derivatives of Human Liver Cytochrome P450. Mechanism-Based Inactivation of CYP 2C19 by Ticlopidine

    • Nguyêt-Thanh Ha-Duong, Sylvie Dijols, Anne-Christine Macherey, Patrick M. Dansette, Daniel Mansuy
    Pages 145-148

  20. Microperoxidase 8 (MP8) as a Convenient Model for Hemoproteins: Formation and Characterisation of New Iron(II)-Nitrosoalkane Complexes of Biological Relevance

    • Remy Ricoux, Jean-Luc Boucher, Daniel Mansuy, Jean-Pierre Mahy
    Pages 149-152
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Keywords

Editors and Affiliations

  • Université René Descartes, Paris, France

    Patrick M. Dansette

  • Rutgers University and The Environmental & Occupational Health Sciences Institute, Piscataway, USA

    Robert Snyder

  • CNRS, Paris, France

    Marcel Delaforge

  • University of Surrey, Guildford, Surrey, England

    G. Gordon Gibson

  • Institute of Toxicology and Environmental Health, The Technical University of Munich, Munich, Germany

    Helmut Greim

  • Medical University of South Carolina, Charleston, USA

    David J. Jollow

  • University of Texas, Austin, USA

    Terrence J. Monks

  • University of Arizona, Tucson, USA

    I. Glenn Sipes

Bibliographic Information

  • Book Title: Biological Reactive Intermediates Vi

  • Book Subtitle: Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases

  • Editors: Patrick M. Dansette, Robert Snyder, Marcel Delaforge, G. Gordon Gibson, Helmut Greim, David J. Jollow, Terrence J. Monks, … I. Glenn Sipes

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-0667-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2001

  • Hardcover ISBN: 978-0-306-46659-5Published: 30 November 2001

  • Softcover ISBN: 978-1-4613-5185-6Published: 21 October 2012

  • eBook ISBN: 978-1-4615-0667-6Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XV, 728

  • Topics: Biochemistry, general, Pharmacology/Toxicology, Pathology, Oncology

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