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The Physiological Genomics of the Critically Ill Mouse

  • Book
  • © 2004

Overview

Editors:
  1. Can Ince

    1. Department of Physiology Academic Medical Center, University of Amsterdam, The Netherlands

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Part of the book series: Basic Science for the Cardiologist (BASC, volume 16)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Physiological Monitoring of the Mouse

    1. Front Matter

      Pages 1-1
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    2. Assessment of Quality in Commercially Supplied Genetically Modified Animals

      • Adrian A. Deeny
      Pages 3-9

    3. Cannulation Techniques for Multiple Blood Withdrawal in Mice

      • Edwin Spoelstra, René Remie
      Pages 11-21

    4. Mouse Anesthesia in Relation to Optimal Hemodynamics

      • Coert J. Zuurbier, Vanessa M. Emons, Anneke Koeman, Can Ince
      Pages 23-34

    5. Mechanical Ventilation of Mice

      • Lothar A. Schwarte, Can Ince
      Pages 35-51

    6. Mouse Echocardiography

      • Attila Kovacs, Michael Courtois
      Pages 53-71

    7. Optical Spectroscopy in Mice

      • Egbert G. Mik, Can Ince
      Pages 73-88

    8. ECG Monitoring and Analyses in Mice

      • Ivo Amende, J. Matthew Dubach, Katrina Piskorski, James P. Morgan, Thomas G. Hampton
      Pages 89-100

    9. High-Definition Magnetic Resonance of Genetically Modified Mice

      • Klaas Nicolay, Gustav J. Strijkers, Jeanine J. Prompers, Maarten R. Drost
      Pages 101-117

    10. Pet Studies in the Mouse

      • Adriaan A. Lammertsma
      Pages 119-126

    11. Mouse Telemetry for Long-Term Monitoring

      • Klaas Kramer, Steve Hachtman
      Pages 127-141

  3. Cardiovascular Pathophysiology of the Mouse

    1. Front Matter

      Pages 143-143
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    2. Physiological Genomics Of Reperfusion Injury

      • Thorsten Vowinkel, D. Neil Granger
      Pages 145-158

    3. Inos-Deficient Mice in the Study of Resuscitated Sepsis

      • Steven M. Hollenberg
      Pages 159-177

    4. The Microcirulation in Hypercholesterolemic Mice

      • Alina Constantinescu, Hans Vink
      Pages 179-186

    5. The Mouse in Shock

      • Martin G. Schwacha, Irshad H. Chaudry
      Pages 187-200

    6. Expression Systems to Analyze Transgenes in the Heart

      • Petra E. M. H. Habets, Antoon F. M. Moorman, Vincent M. Christoffels
      Pages 201-210

    7. Structural and Functional Adaptations of the Heart After Coronary Artery Ligation in the Mouse

      • Ben Janssen, Tijl De Celle, Jos Paquay, Jos Smits, Matthijs Blankesteijn
      Pages 211-224

    8. Mouse Models of Sepsis

      • Gerd Albuszies
      Pages 225-238
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Keywords

About this book

The physiological genomics of the cardiovascular system studies the relationship between gene and physiological (dys)function. It is a rapidly developing area of research and distinguishes itself from other areas of molecular medicine by its highly integrative nature. In this multi­ disciplinarian area of the physiological sciences, there is interaction between gene structure and physiological cardiovascular function as well as interactions between the different organs and their physiological compartments. The mouse has played a central role in the study of genomics due to the detailed knowledge of the mouse genome and the wide availability of genetically modified mice. In the past, the mouse had mainly been used in the area of immunology and molecular biology, and physiological interest in the mouse was scarce. As more insight has come into the structural genomics of the mouse, however, it has become increasingly important to understand the relation between gene and physiological function. With this in mind we have been organizing the Amsterdam Mouse Symposia to bring together different disciplines interested in the molecular basis of cardiovascular function (see J. of Clinical and Exp. Pharmacology and rd Physiology (2002) 29:A69-AI02 for the proceedings of the 3 Amsterdam Mouse Symposium and Basic Research in Cardiology (2000) 95:492-535 for nd the proceedings of the 2 symposium).

Editors and Affiliations

  • Department of Physiology Academic Medical Center, University of Amsterdam, The Netherlands

    Can Ince

Bibliographic Information

  • Book Title: The Physiological Genomics of the Critically Ill Mouse

  • Editors: Can Ince

  • Series Title: Basic Science for the Cardiologist

  • DOI: https://doi.org/10.1007/978-1-4615-0483-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2004

  • Hardcover ISBN: 978-1-4020-7641-1Published: 30 November 2003

  • Softcover ISBN: 978-1-4613-5099-6Published: 05 November 2012

  • eBook ISBN: 978-1-4615-0483-2Published: 06 December 2012

  • Series ISSN: 1566-0753

  • Edition Number: 1

  • Number of Pages: XVIII, 386

  • Topics: Cardiology, Life Sciences, general

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