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  • © 2004

Antibodies

Volume 1: Production and Purification

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiv
  2. Antibody Fragments

    • David J. Glover, David P. Humphreys
    Pages 25-73
  3. Scale-Up of Antibody Purification

    • Lothar R. Jacob, Matthias Frech
    Pages 101-131
  4. Purification of Antibodies by Chromatographic Methods

    • Caroline Vandevyver, Ruth Freitag
    Pages 133-168
  5. Quality Control of Antibodies for Human Use

    • Andreas Richter, Mark Jostameling, Kerstin Müller, Andreas Herrmann, Martin Pitschke
    Pages 169-187
  6. Expression of Human Anti-Rh (D) Monoclonal Antibodies into Different Cell Lines: Influence on their Functional Properties

    • Christophe de Romeuf, Christine Gaucher, Arnaud Glacet, Sylvie Jorieux, Philippe Klein, Dominique Bourel
    Pages 189-198
  7. Monoclonal Antibody Production: Minimising Virus Safety Issues

    • John Bray, Malcolm K. Brattle
    Pages 199-225
  8. Contract Manufacturing of Biopharmaceutical Grade Antibodies

    • Leo A. van der Pol, Douwe F. Westra
    Pages 227-247
  9. The Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies

    • David B. Haughey, Paula M. Jardieu
    Pages 249-273
  10. Back Matter

    Pages 289-314

About this book

If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including:
-concepts in development of manufacturing strategies,
-importance of antibody fragments,
-application of chromatography method development,
-quality control,
-effect of expression on antibody properties,
-virus removal and safety,
-pharmacokinetics,
-regulatory aspects.

Editors and Affiliations

  • Littlebourne, UK

    G. Subramanian

Bibliographic Information

  • Book Title: Antibodies

  • Book Subtitle: Volume 1: Production and Purification

  • Editors: G. Subramanian

  • DOI: https://doi.org/10.1007/978-1-4419-8875-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2004

  • Hardcover ISBN: 978-0-306-48245-8Published: 31 March 2004

  • Softcover ISBN: 978-1-4613-4701-9Published: 18 September 2012

  • eBook ISBN: 978-1-4419-8875-1Published: 07 March 2013

  • Edition Number: 1

  • Number of Pages: XIV, 314

  • Topics: Pharmacy, Immunology, Pharmacology/Toxicology, Biomedical Engineering and Bioengineering

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access