Analysis of Physiological Systems

1. Front Matter

   Pages i-xvi

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2. The Problem of System Identification in Physiology

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 1-10

3. Analysis of Physiological Signals

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 11-69

4. Traditional Approaches to Physiological System Identification

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 71-129

5. The White-Noise Method in System Identification

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 131-180

6. Applicability of the White-Noise Method and the Use of Quasiwhite Test Signals

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 181-221

7. Methods of Computation of System Kernels

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 223-276

8. Errors in the Estimation of System Kernels

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 277-346

9. Tests and Analyses Preliminary to Identification Experiment

   • Panos Z. Marmarelis, Vasilis Z. Marmarelis

   Pages 347-375

10. Peeking into the Black Box

    • Panos Z. Marmarelis, Vasilis Z. Marmarelis

    Pages 377-402

11. Applications of the White-Noise Method to Neural Systems

    • Panos Z. Marmarelis, Vasilis Z. Marmarelis

    Pages 403-437

12. Physiological Systems Requiring Special Treatment

    • Panos Z. Marmarelis, Vasilis Z. Marmarelis

    Pages 439-460

13. Dialogue for Epilogue

    • Panos Z. Marmarelis, Vasilis Z. Marmarelis

    Pages 461-465

14. Back Matter

    Pages 467-487

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In studying physiological systems bioscientists are continually faced with the problem of providing descriptions of cause-effect relationships. This task is usually carried out through the performance of stimulus-response experiments. In the past, the design of such experiments has been ad hoc, incomplete, and certainly inefficient. Worse yet, bioscientists have failed to take advantage of advances in fields directly related to their problems (specifically, advances in the area of systems analysis). The raison d'etre of this book is to rectify this deficiency by providing the physiologist with methodological tools that will be useful to him or her in everyday labora­ tory encounters with physiological systems. The book was written so that it would be practical, useful, and up-to­ date. With this in mind, parts of it give step-by-step descriptions of in the laboratory. It is hoped that this systematic procedures to be followed will increase the usefulness of the book to the average research physiologist and, perhaps, reduce the need for in-depth knowledge of some of the associated mathematics. Even though the material deals with state-of-the­ art techniques in systems and signal analysis, the mathematical level has been kept low so as to be comprehensible to the average physiologist with no extensive training in mathematics. To this end, mathematical rigor is often sacrificed readily to intuitive simple arguments.

• art
• experiment
• mathematics
• physiology
• research

• School of Medicine, University of California, Los Angeles, Los Angeles, USA

  Panos Z. Marmarelis

• School of Engineering and Applied Science, California Institute of Technology, Pasadena, USA

  Vasilis Z. Marmarelis

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