Neuropharmacology and Behavior

1. Front Matter

   Pages i-xii

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2. Amphetamine Psychosis—A Model for Paranoid Schizophrenia?

   • Kenneth M. Woodrow, Ann Reifman, Richard Jed Wyatt

   Pages 1-22

3. Hypersensitive Serotonergic Receptors Involved in Clinical Depression—A Theory

   • M. H. Aprison, Ryo Takahashi, K. Tachiki

   Pages 23-53

4. The Organization of Central Catecholamine Neuron Systems

   • Robert Y. Moore, Lawrence F. Kromer

   Pages 55-87

5. Effect of Reserpine on Monoamine Synthesis and on Apparent Dopaminergic Receptor Sensitivity in Rat Brain

   • Arvid Carlsson, Margit Lindqvist

   Pages 89-102

6. The Induction of Tyrosine-3-monooxygenase in Rat Adrenal Medulla: A Model for the Transsynaptic Regulation of Gene Expression

   • A. Guidotti, E. Costa

   Pages 103-125

7. The Neurophysiological Effects of Diphenylhydantoin and Their Relationship to Anticonvulsant Activity

   • G. F. Ayala, D. Johnston

   Pages 127-152

8. Some Molecular Aspects of Neural Mechanisms

   • J. R. Smythies

   Pages 153-174

9. Seven Neurons of Psychopharmacology: Adaptive Regulation in Biogenic Amine Neurons

   • Arnold J. Mandell

   Pages 175-190

10. Epilogue

    • Seymour Kety

    Pages 191-192

11. Back Matter

    Pages 193-223

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Science lost one of its distinguished researchers in the fields of biological psychiatry and neuropsychopharmacology on March 4, 1975, with the death of Harold Himwich. Some of his colleagues, friends, and former associates have expressed their esteem for this gentle person by the contribution of chapters in this book. Since this book can represent only an incomplete indication of Harold Himwich's influence, the editors have included his complete bibliography at the end of this volume. Harold Himwich's research career was divided into several phases, some of which overlapped. Starting with his first paper on rhabdomyoma of the ovary in 1920, he was entranced by research as well as by the puzzles and results which it promised. During the period that he was a resident and house officer at Bellevue Hospital in New York, he studied the physiology of muscular exercise. This work led him into studies of exercise in various types of disease. With Meyerhoff in Kiel, Germany, he began studying the respiratory quotient of muscle, and after returning to this country, he produced a number of papers on respiratory quotients of various organs including the brain.

• brain
• muscle
• neuropharmacology
• physiology
• psychiatry
• psychopharmacology
• research

• The Marine Biomedical Institute Department of Human Biological Chemistry and Genetics and Department of Neurology, University of Texas Medical Branch, Galveston, USA

  Bernard Haber

• Institute of Psychiatric Research and Departments of Psychiatry and Biochemistry, Indiana University School of Medicine, Indianapolis, USA

  M. H. Aprison

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