Overview
- Editors:
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Michael R. Rosen
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Columbia University, New York, USA
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Brian F. Hoffman
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Columbia University, New York, USA
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Table of contents (16 chapters)
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Pathophysiology
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- Michael R. Rosen, Brian F. Hoffman
Pages 1-19
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Cardiac Autonomic Interactions and their Pharmacologic Modification
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- John A. Oates, David Robertson, Alastair J. J. Wood, Raymond L. Woosley
Pages 145-169
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Therapy of Cardiac Arrhythmias
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- Penelope A. Boyden, Andrew L. Wit
Pages 171-234
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- Leonard S. Gettes, James R. Foster, Ross J. Simpson Jr.
Pages 235-298
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- Mark E. Josephson, Alden H. Harken
Pages 337-385
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Therapy of Cardiac Failure and Ischemia
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- Alan S. Nies, Gwynne Neufeld
Pages 435-451
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- Eric S. Williams, Charles Fisch
Pages 453-479
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- David W. Snyder, Burton E. Sobel
Pages 481-535
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- Richard O. Russell Jr., Charles E. Rackley, Nicholas T. Kouchoukos
Pages 537-550
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Back Matter
Pages 551-568
About this book
Cardiac therapy has become ever more complex during the past quarter century. For example, 25 years ago, the therapy of cardiac failure was largely limited to digitalis, a very few diuretics, salt restriction, and general supportive measures. Antiarrhythmic therapy involved - in the main - quinidine, procainamide, and digitalis, and questions such as which arrhythmia to treat and how to measure drug efficacy had been addressed in elementary fashion only. Cardiac surgery was limited largely to congenital and valvular heart disease; the areas of cardiac pacemaker therapy, defibrillation and other forms of electrical diagnosis and therapy were rudimentary. The expansion of support of cardiovascular research by the National Institutes of Health as well as by institutional sources following World War II has led to major successes in clinical health care delivery and improved technology made available to clinical investigators. In reviewing progress over the past 25 years, we have been particularly impressed by one observation: this is the important interaction that has developed between studies of pathophysiology and the delivery of appropriate cardiac therapy.