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Calcium Antagonists

Mechanism of Action on Cardiac Muscle and Vascular Smooth Muscle

  • Book
  • © 1984

Overview

Editors:
  1. Nicholas Sperelakis

    1. Department of Physiology, University of Cincinnati College of Medicine, Cincinnati, USA

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  2. James B. Caulfield
    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 39)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xiii
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  2. INTRODUCTION: Role of Ca++ in Contraction, and Wide Variety of Effects of Calcium Antagonists

    1. INTRODUCTION: Role of Ca++ in Contraction, and Wide Variety of Effects of Calcium Antagonists

      • Nick Sperelakis
      Pages 1-9

  3. Basic Science Aspects

    1. Calcium Channel Antagonists: Pharmacologic and Radioligand Binding Approaches to Mechanisms of Action

      • D. J. Triggle, R. A. Janis
      Pages 11-20

    2. Effects of Calcium Slow Channel Blockers on the Slow Action Potentials of Cardiac Muscle and Vascular Smooth Muscle

      • Nick Sperelakis
      Pages 21-45

    3. Voltage Clamp Studies Of Calcium Channel Blockage in the Heart

      • R. S. Kass, M. C. Sanguinetti
      Pages 47-62

    4. Mechanisms of Selective CA Antagonist-Induced Vasodilation

      • C. Van Breemen, C. Cauvin, O. Hwang, P. Leyten, S. Lukeman, K. Meisheri et al.
      Pages 63-76

    5. Action of Calcium Slow Channel Inhibitors on Cardiac and Vascular Smooth Muscle Membranes

      • Mohammed A. Matlib, Arnold Schwartz, A. DePover, G. Grupp, I. Grupp, S. W. Lee et al.
      Pages 77-93

  4. Clinical Science Aspects

    1. Effects of Calcium Antagonists on Injured Cells

      • Philip D. Henry
      Pages 94-100

    2. Antianginal Effects of Calcium Antagonists

      • John S. Schroeder
      Pages 101-110

    3. Clinical Electrophysiology of the Calcium Antagonists

      • E. Rowland, D. M. Krikler
      Pages 111-117

  5. Invited Poster Session

    1. Basic Features of The Frequency- and Voltage-Dependent Block By D600 of Calcium Channels in Ventricular Muscle

      • Terence F. McDonald, Dieter Pelzer, Wolfgang Trautwein
      Pages 118-136

    2. Evidence for a Modulated Receptor Mechanism of Calcium Channel Blockade

      • C. W. Clarkson, M. Inazawa, S. Kanaya, L. M. Hondeghem, B. G. Katzung
      Pages 137-151

    3. Effects of Calcium Antagonistic Drugs on Various Heart Tissues, Including Blockade of the Slow Channels and Depression of Postdrive Hyperpolarization.

      • P. A. Molyvdas, N. Sperelakis
      Pages 153-178

    4. Effect of Nifedipine on Rat Papillary Muscle and Perfused Heart

      • P. Braveny, J. S. Juggi, G. Telahoun
      Pages 179-185

    5. Excitation-Contraction Coupling in Rat Myocardium: Modulation with Verapamil and Calcium

      • Joseph M. Capasso
      Pages 187-202

    6. The Potentially Direct Role of Intracellular Calcium Overload in the Electrophysiology of Cardiac Ischemia

      • William T. Clusin, Maurice Buchbinder, R. Hardwin Mead
      Pages 203-217

    7. Mechanisms of the Beneficial Effects of Some Ca2+ Antagonists on the Ca2+-Paradox in Myocardium

      • N. S. Dhalla, P. K. Singal, S. Takeo, D. B. McNamara
      Pages 219-227

    8. Comparative Effects of Ca Slow Channel Blockers on the Hamster Hereditary Cardiomyopathy

      • G. Jasmin, L. Proschek
      Pages 229-239

    9. Calcium Antagonistic Agents: Uptake into Various Muscles and their Effects on Calcium Binding

      • David C. Pang, Nick Sperelakis
      Pages 241-256

    10. The Effect of Verapamil on Lanthanum (La3+) Binding in the Isolated Rabbit Heart

      • S. A. Barman, J. T. Saari, M. D. Olson
      Pages 257-273
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Keywords

Editors and Affiliations

  • Department of Physiology, University of Cincinnati College of Medicine, Cincinnati, USA

    Nicholas Sperelakis

Bibliographic Information

  • Book Title: Calcium Antagonists

  • Book Subtitle: Mechanism of Action on Cardiac Muscle and Vascular Smooth Muscle

  • Editors: Nicholas Sperelakis, James B. Caulfield

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-3810-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1984

  • Hardcover ISBN: 978-0-89838-655-4Published: 31 May 1984

  • Softcover ISBN: 978-1-4613-3812-3Published: 12 October 2011

  • eBook ISBN: 978-1-4613-3810-9Published: 12 June 2019

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XIV, 352

  • Topics: Cardiology

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