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  • Book
  • © 1983

In Vitro Toxicity Testing of Environmental Agents

Current and Future Possibilities Part A: Survey of Test Systems

Editors:

  1. Alan R. Kolber

    1. Research Triangle Institute, North Carolina, USA

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  2. Thomas K. Wong

    1. National Institute of Environmental Health Sciences (BRAP), North Carolina, USA

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  3. Lester D. Grant

    1. U.S. Environmental Protection Agency, North Carolina, USA

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  4. Robert S. DeWoskin

    1. Research Triangle Institute, North Carolina, USA

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  5. Thomas J. Hughes

    1. Research Triangle Institute, North Carolina, USA

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Part of the book series: Nato Conference Series (NATOCS, volume 5)

Part of the book sub series: II Systems Science (SYSC)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xix
    PDF

  2. Survey of Test Systems

    1. Front Matter

      Pages 1-1
      PDF

    2. Mutagenesis Testing: Prokaryotic Systems

      5. The Use of <u>Salmonella</u> Bacteriophage P22 to Study the Multiple Mechanisms of Acridine-Induced Damage
        • Edward Loechler, Harlee Strauss, Jerry L. Bryant Jr., Jonathan King
        Pages 79-109

    3. Mutagenesis Testing: Eukaryotic Systems

      3. The Maize-Microbe Bioassay: A Unique Approach to Environmental Mutagenesis
        • James M. Gentile, Michael J. Plewa
        Pages 151-165
      6. Metabolic Activation and Mutagenic Properties of Procarcinogens in <u>Drosophila</u>
        • E. Vogel, J. A. Zijlstra, W. G. H. Blijleven, D. D. Breimer
        Pages 215-231
      8. Quantitative Mammalian Cell Mutagenesis and Mutagen Screening: Study with Chinese Hamster Ovary Cells
        • Abraham W. Hsie, J. Patrick O’Neill, Juan R. San Sebastian, Patricia A. Brimer, Eng-Lai Tan
        Pages 283-302

    4. In Vitro Carcinogenesis Testing

      1. <u>In</u> <u>Vitro</u> Carcinogenesis with Cell Lines
        • Charles Heidelberger
        Pages 305-315

    5. Neurobehavioral Toxicity Testing

      1. Behavioral Assays in Environmental Toxicology
        • Bernard Weiss
        Pages 355-381
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About this book

These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa­ tion and ideas on the current approaches (both scientific and po­ litical) for toxic assessment of environmental agents. The poten­ tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short­ term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car­ cinogenesis, mutagenesis, and transformation; (3) bacterial muta­ genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.
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Keywords

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Editors and Affiliations

  • Research Triangle Institute, North Carolina, USA

    Alan R. Kolber, Robert S. DeWoskin, Thomas J. Hughes

  • National Institute of Environmental Health Sciences (BRAP), North Carolina, USA

    Thomas K. Wong

  • U.S. Environmental Protection Agency, North Carolina, USA

    Lester D. Grant

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Bibliographic Information

  • Book Title: In Vitro Toxicity Testing of Environmental Agents

  • Book Subtitle: Current and Future Possibilities Part A: Survey of Test Systems

  • Editors: Alan R. Kolber, Thomas K. Wong, Lester D. Grant, Robert S. DeWoskin, Thomas J. Hughes

  • Series Title: Nato Conference Series

  • DOI: https://doi.org/10.1007/978-1-4613-3566-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1983

  • Hardcover ISBN: 978-0-306-41123-6Due: 01 January 1983

  • Softcover ISBN: 978-1-4613-3568-9Published: 05 November 2011

  • eBook ISBN: 978-1-4613-3566-5Published: 08 March 2013

  • Edition Number: 1

  • Number of Pages: XX, 553

  • Topics: Physics, general

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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