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Plasma Fractionation and Blood Transfusion

Proceedings of the Ninth Annual Symposium on Blood Transfusion, Groningen, 1984, organized by the Red Cross Blood Bank Groningen-Drenthe

  • Conference proceedings
  • © 1985

Overview

Editors:
  1. C. Th. Smit Sibinga

    1. Red Cross Blood Bank Groningen-Drenthe, Groningen, The Netherlands

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  2. P. C. Das

    1. Red Cross Blood Bank Groningen-Drenthe, Groningen, The Netherlands

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    You can also search for this editor in PubMed   Google Scholar

  3. S. Seidl

    1. Red Cross Blood Transfusion Service Hessen, Frankfurt am Main, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Hematology and Immunology (DIHI, volume 13)

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Table of contents (29 papers)

  1. Front Matter

    Pages I-XIII
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  3. Technology of plasma fractionation

    1. Front Matter

      Pages 41-41
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    2. Small Pool versus Large Pool in Plasma Fractionation: Reevaluation of a Concept

      • C. Th. Smit Sibinga, P. C. Das
      Pages 43-46

    3. Ethanol Fractionation of Human Plasma: An Overview

      • H. G. J. Brummelhuis
      Pages 47-56

    4. Control of Large-Scale Plasma Thawing

      • P. R. Foster, A. J. Dickson
      Pages 57-65

    5. Contributions to the Optimization of Factor VIII Production: Cryoprecipitation and Controlled Pore Glass Adsorption

      • J. Over, M. P. J. Piët, J. A. Loos, H. P. J. Henrichs, P. J. Hoek, M. A. von Meyenfeldt et al.
      Pages 67-78

    6. Chromatographic Methods of Plasma Fractionation

      • J. M. Curling
      Pages 79-81

    7. Polyelectrolyte Fractionation Technology

      • S. M. Middleton
      Pages 83-88

    8. Recombinant DNA Technology for the Production of Plasma Proteins

      • W. D. Lake, W. R. Srigley
      Pages 89-95

    9. Column Ion Exchange Chromatographic Production of Albumin, IV ISG and Factor IX from 75,000 to 100,000 Litres of Plasma per Year

      • A. D. Friesen
      Pages 97-103

    10. Large Scale Chromatographic Experiments for Plasma Fractionation

      • F. Haskó, K. Kristóf, M. Salamon, P. Dobó
      Pages 105-114

    11. Discussion: Moderators: J.K. Smith, H.G.J. Brummelhuis

      • C. Th. Smit Sibinga, P. C. Das, S. Seidl
      Pages 115-123

  4. Safety aspects

    1. Front Matter

      Pages 125-125
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    2. Preservation of Structure and Function During Isolation of Human Plasma Proteins

      • J. J. Morgenthaler, U. E. Nydegger
      Pages 127-138
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Keywords

About this book

Plasma fractionation and blood transfusion are inherently linked. Blood­ bankers need to have a sincere interest in fractionation and purification techniques in order to understand the need for carefully controlled source material collection and initial processing. Developments point to a shift in technology, implementation and application of plasma fractions to be produced, such that early anticipation from both bloodbankers and fractionators in a joint interest and effort are needed. As usual there is good news and bad news. We are referring in that respect to the exciting presentation about the future of bloodbanking. Although the blood donor still plays a major role in bloodbanking, new technologies could terminate the conventional blood transfusion service in the next 20-40 years. Sooner or later DNA technology will play an important role in bloodbanking and bloodbankers will have to deal with cultivated red cells as a replacement of our donor blood. Several fractionation techniques like column chromatography, controlled pore glass chromatography, heparin double cold precipitation technology and polyelectrolite fractionation are available, which may result in better yields for some of the plasma proteins. These techniques are likely to replace in part the old Cohn fractionation in the near future.

Editors and Affiliations

  • Red Cross Blood Bank Groningen-Drenthe, Groningen, The Netherlands

    C. Th. Smit Sibinga, P. C. Das

  • Red Cross Blood Transfusion Service Hessen, Frankfurt am Main, Germany

    S. Seidl

Bibliographic Information

  • Book Title: Plasma Fractionation and Blood Transfusion

  • Book Subtitle: Proceedings of the Ninth Annual Symposium on Blood Transfusion, Groningen, 1984, organized by the Red Cross Blood Bank Groningen-Drenthe

  • Editors: C. Th. Smit Sibinga, P. C. Das, S. Seidl

  • Series Title: Developments in Hematology and Immunology

  • DOI: https://doi.org/10.1007/978-1-4613-2631-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1985

  • Softcover ISBN: 978-1-4612-9644-7Published: 04 October 2011

  • eBook ISBN: 978-1-4613-2631-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 250

  • Topics: Hematology

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