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Role of RNA and DNA in Brain Function

A Molecular Biological Approach

  • Book
  • © 1986

Overview

Editors:
  1. Antonio Giuditta

    1. Department of General and Environmental Physiology, University of Naples, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Barry B. Kaplan

    1. Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Claire Zomzely-Neurath

    1. Office of Naval Research London Branch, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Topics in the Neurosciences (TNSC, volume 3)

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Brain Gene Products

    1. A Comparative Study of the Diversity of Gene Expression in Brain

      • B. B. Kaplan, A. E. Gioio, C. Perrone Capano, A. Giuditta
      Pages 1-9

    2. Messenger RNA in the Brain

      • W. E. Hahn, N. Chaudhari, J. Sikela, G. Owens
      Pages 10-22

    3. Gene Expression in the Mammalian Brain

      • J. G. Sutcliffe, R. D. McKinnon, A.-P. Tsou
      Pages 23-31

    4. Expression of Brain-Specific Proteins

      • R. J. Milner
      Pages 32-41

    5. Messenger RNA is Present in the Axoplasm of Squid Giant Axons

      • A. Giuditta, T. Hunt, C. Perrone Capano, L. Santella, B. B. Kaplan
      Pages 42-56

  3. Cloning and Expression of Brain Genes

    1. Molecular Genetics of Tyrosine Hydroxylase

      • J. Mallet, A. Berod, F. Blanot, C. Boni, M. Buda, N. Faucon Biguet et al.
      Pages 57-70

    2. Analysis of Synapsin i and G-Substrate Gene Expression by cDNA Cloning and in Situ Hybridization Histochemistry

      • L. J. DeGennaro, M. W. Kilimann, C. A. Haas
      Pages 71-80

    3. The Expression of Microtubule Proteins During the Development of the Nervous System

      • I. Ginzburg, U. Z. Littauer
      Pages 81-89

    4. Regulation of Expression of the Human Proenkephalin Gene in Heterologous Cell Systems

      • E. Herbert, M. Comb, G. Thomas, D. Liston, A. Seasholtz, H. Rosen et al.
      Pages 90-111

    5. The Regulation of Proopiomelanocortin Gene Expression by Estrogen in the Rat Hypothalamus

      • J. L. Roberts, J. N. Wilcox, M. Blum
      Pages 112-122

  4. The Molecular Biology of Neurological Diseases

    1. DNA Analysis of Duchenne and Becker Muscular Dystrophies

      • K. E. Davies, H. R. Dorkins, S. McGlade, S. P. Ball, S. J. Kenwrick, T. Smith et al.
      Pages 123-130

    2. Genetic Analysis of the Fragile X-Mental Retardation Syndrome with Polymorphic DNA Markers

      • I. Oberlé, G. Camerino, B. Arveiler, J. Boue, M. G. Mattéi, J. F. Mattéi et al.
      Pages 131-141

    3. Brain Messenger RNA in Alzheimer’s Disease

      • M. R. Morrison, W. S. T. Griffin, C. L. White III
      Pages 142-159

    4. The Effect of Trisomy-21 (Down’s Syndrome) on Brain Transcription

      • L. Lim, C. Hall, T. Leung, S. Whatley
      Pages 160-173

  5. Brain DNA

    1. Neuronal Chromatin Structure and DNA Content

      1. Neuronal Chromatin during Development
        • I. R. Brown
        Pages 174-181
      2. Post-Translational Modifications of Chromosomal Proteins in Neuronal and Glial Nuclei from Developing Rat Brain
        • I. Serra, A. M. Giuffrida
        Pages 182-196
      3. DNA Content in Neurons
        • G. Bernocchi, E. Scherini
        Pages 197-210

    2. Enzymes Related to DNA Metabolism

      1. Enzymology of DNA Replication and Repair in Brain
        • C. C. Kuenzle
        Pages 211-223
      2. Brain Dnases and their Functional Importance
        • K. Subba Rao
        Pages 224-232
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Keywords

About this book

There was once an old Chinese man working on a hill with a boy. On the plain, near the sea, rested the village, the inhabitants eagerly engaged in their daily activities. Suddenly, the old man noticed that a huge wave, far distant in the sea, was approaching the shore endangering all. The only safe place was the hill. So, he began waving his hands and screaming aloud, to no avail. The villagers were too busy with their own work and paid little heed to the old man, who was considered a bit eccentric. But soon flames were on the hill, the wheat fields ablaze. The old man had resorted to this ultimate step to alert his fellow citizens. Now, they all went running towards him, angry about their burning crop, and in the process, avoided the imminent danger. For some mysterious reason, my mind focused on this story prior to the Symposium on the Role of DNA, which took place in Ravello, Italy at the end of May 1985. Having made a call for people to meet and reflect for a few days, the analogy began to take shape. Ravello was indeed a hill, magically overlooking the sea from medieval quarters. True, its countryside is filled with vineyards, not wheat fields, but that is an improvement on the story. However, what was the wave? Perhaps, the growing amount of data on cloned brain genes that threatens to engulf neurobiologists.

Editors and Affiliations

  • Department of General and Environmental Physiology, University of Naples, Italy

    Antonio Giuditta

  • Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, USA

    Barry B. Kaplan

  • Office of Naval Research London Branch, UK

    Claire Zomzely-Neurath

Bibliographic Information

  • Book Title: Role of RNA and DNA in Brain Function

  • Book Subtitle: A Molecular Biological Approach

  • Editors: Antonio Giuditta, Barry B. Kaplan, Claire Zomzely-Neurath

  • Series Title: Topics in the Neurosciences

  • DOI: https://doi.org/10.1007/978-1-4613-2321-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1986

  • Hardcover ISBN: 978-0-89838-814-5Published: 31 July 1986

  • Softcover ISBN: 978-1-4612-9427-6Published: 28 August 2013

  • eBook ISBN: 978-1-4613-2321-1Published: 06 December 2012

  • Series ISSN: 0897-3946

  • Edition Number: 1

  • Number of Pages: XVI, 322

  • Topics: Neurosciences

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