Alzheimer’s and Parkinson’s Diseases

1. Front Matter

   Pages i-xvi

   PDF

2. Welcoming Address

   1. Welcoming Address

      • I. Hertman

      Pages 1-3

3. Alzheimer’s and Parkinson’s Disease: Anatomical, Pathological and Biochemical Aspects

   1. Cholinergic Systems in the Brain and Spinal Cord: Anatomic Organization and Overview of Functions

      • Larry L. Butcher, Nancy J. Woolf

      Pages 5-16

   2. Histopathology of the Basal Forebrain and its Targets in Alzheimer Dementia

      • Roland W. Jacobs, Larry L. Butcher

      Pages 17-23

   3. Clinical, Pathological and Biochemical Aspects of Alzheimer’s Disease

      • Henryk M. Wisniewski

      Pages 25-36

   4. Molecular Properties of Paired Helical Filaments and Senile Plaque Amyloid Fibers in Alzheimer’s Disease

      • Dennis J. Selkoe, Carmela Abraham, C. G. Rasool

      Pages 37-42

   5. Structural and Chemical Aspects of Cortical Pathology in Alzheimer’s Disease

      • James Edwardson, Robert Perry, John Candy, Arthur Oakley, Elaine Perry

      Pages 43-52

   6. Cholinergic and Non-Cholinergic Neurotransmitter Hypotheses for Alzheimer’s Disease

      • D. M. Bowen, P. T. Francis, A. M. Palmer

      Pages 53-61

   7. Brain Topochemistry of Cholinergic and Monoaminergic Parameters in Alzheimer’s Disease

      • B. Winblad, R. Adolfsson, A. Nordberg, P. Nyberg

      Pages 63-68

   8. The “Autocannibalism” of Choline-Containing Membrane Phospholipids in the Pathogenesis of Alzheimer’s Disease

      • Richard J. Wurtman, Jan K. Blusztajn, Jean-Claude Maire

      Pages 69-73

   9. Trophic Factors and Neurologic Disease

      • Stanley H. Appel, Yasuko Tomozawa, Robert Bostwick

      Pages 75-84

   10. Neuronal Loss and Neurotransmitter Receptor Alterations in Alzheimer’s Disease

       • Peter J. Whitehouse

       Pages 85-94

   11. Brain Nicotinic and Muscarinic Receptors in Normal Aging and Dementia

       • Agneta Nordberg, Bengt Winblad

       Pages 95-108

   12. Examination of Cholinergic and Neuropeptide Receptor Alterations in Senile Dementia of the Alzheimer’s Type (SDAT)

       • K. Gulya, M. Watson, T. W. Vickroy, W. R. Roeske, R. Perry, E. Perry et al.

       Pages 109-116

   13. Quantitative Autoradiography and Histochemistry in the Human Brain Post Mortem

       • Anat Biegon, Marilyn Wolff

       Pages 117-120

   14. Increased Vasopressin Production in Senescence and Dementia Due to Kidney Changes

       • R. Ravid, D. F. Swaab, E. Fliers, J. E. Hoogendijk

       Pages 121-127

4. Clinical Aspects and Noninvasive Diagnostic Approaches

   1. Clinical Heterogeneity in Patients with Dementia of the Alzheimer Type

      • Richard Mayeux, Yaakov Stern

      Pages 129-134

   2. Patterns of Cognitive Impairment in Patients with Alzheimer’s Disease and Parkinson’s Disease: Are They Similar or Different?

      • Bracha Mildworf, Mordechai Globus, Eldad Melamed

      Pages 135-140

   3. Risk Factors in Alzheimer’s Disease

      • L L Barclay, S Kheyfets, A Zemcov, J P Blass, F H McDowell

      Pages 141-146

   4. Enhancing Communication for the Demented Patient and His Family

      • A. J. Rosin, L. Abramowitz, J. Diamond, S. Beitz, S. Hirsch, S. Rifkin

      Pages 147-153

This book is the outcome of an international conference, held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. This was the 30th in a series of the annual OHOLO Conferences, sponsored by the Israel Institute for Biological Research. Participants in this Conference consisted of scientists from four­ teen countries; represented a broad spectrum of research interests; and included a well-balanced representation from academia, clinical institutions and pharmaceutical industry. The book includes talks, poster sessions, and a comprehensive general discussion, all from the proceedings of this conference. In the interest of assuring a rapid publication of the novel infor­ mation reviewed, this book has been prepared in camera-ready format. We are cognizant of the fact that several typographical errors may exist in the text, and that there are variations in style and typeface of the var­ ious chapters. This, we felt, was a reasonable compromise for the sake of speed and efficient transmission of valuable scientific information. No­ body is perfect . •••• The success of the conference, and hence the quality of this book are attributable to the extensive efforts of a large number of extremely capable individuals. These include members of the Scientific Organizing Committee, and the Technical staff of the OHOLO Organization. Of course, the conference could not have succeeded without the high quality of the presentations, and the enthusiastic participation of the contributing scientists.

• blood
• brain imaging
• cell
• evaluation
• imaging
• infection
• laser
• magnetic resonance
• neuroimaging
• neurotransmitter
• population
• production
• tomography
• viral infection
• virus
• infectious diseases

• Israel Institute for Biological Research, Ness-Ziona, Israel

  Abraham Fisher, Chaim Lachman

• Loyola University Stritch School of Medicine, Chicago, USA

  Israel Hanin

Policies and ethics