Skip to main content
SpringerLink
Log in

Malignant Hyperthermia

  • Book
  • © 1987

Overview

Editors:
  1. Beverley A. Britt

    1. Department of Anaesthesia and Pharmacology, University of Toronto, Toronto, Canada
      Toronto General Hospital, Toronto, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xxii
    Download chapter PDF

  2. Malignant Hyperthermia — The Acute Crisis

    • D. J. Steward, G. A. R. O’Connor
    Pages 1-10

  3. Aetiology and Pathophysiology of Malignant Hyperthermia

    • B. A. Britt
    Pages 11-42

  4. Skeletal Muscle Sarcoplasmic Reticulum in the Malignant Hyperthermia Syndrome

    • T. E. Nelson
    Pages 43-78

  5. Mitochondria and Malignant Hyperthermia

    • K. S. Cheah
    Pages 79-102

  6. Porcine Malignant Hyperthermia—The Saga of the “Hot” Pig

    • G. G. Harrison
    Pages 103-136

  7. Malignant Hyperthermia in Animals Other Than Swine

    • L. Klein, H. Rosenberg
    Pages 137-154

  8. Inheritance of Malignant Hyperthermia—A Review of Published Data

    • W. Kalow
    Pages 155-180

  9. Clinical Assessment of Malignant Hyperthermia Patients

    • S. M. Muldoon, H. M. Carlin
    Pages 181-192

  10. Muscle Assessment of Malignant Hyperthermia Patients

    • B. A. Britt
    Pages 193-267

  11. The European MH Group: Protocol for in Vitro Diagnosis of Susceptibility to MH and Preliminary Results

    • H. Ording
    Pages 269-277

  12. Diagnosis of Malignant Hyperthermia in Japan by the Skinned Fibre Test

    • H. Kikuchi, K. Matsui, M. Morio
    Pages 279-294

  13. Microscopy in Malignant Hyperthermia Investigation

    • D. G. F. Harriman
    Pages 295-308

  14. Counselling of Malignant Hyperthermic Susceptible Individuals

    • A. K. W. Brownell
    Pages 309-323

  15. Dantrolene—An Update

    • B. A. Britt
    Pages 325-367

  16. Anaesthesia for Malignant Hyperthermia Susceptible Patients

    • J. Lerman, J. E. S. Relton
    Pages 369-392

  17. Treatment of Acute Hyperthermia Crises

    • D. E. Jones, J. F. Ryan
    Pages 393-406

  18. Back Matter

    Pages 407-420
    Download chapter PDF
Back to top

Keywords

About this book

A HISTORY OF MALIGNANT HYPERTHERMIA Malignant hyperthermia (MH) is a hereditary disorder of muscle. Undoubtedly, individuals have possessed this trait since time immemorial. However, because the trait is usually only unmasked in the presence of potent inhalational anaesthetic agents or non-depolarizing skeletal muscle relaxants, the existence of malignant hyperthermia was not suspected until we" after the dawn of the modern anaesthetic era. In the early years of ether and chloroform anaesthesia, monitoring was minimal. Body temperature was never measured. A finger on the pulse, and observation of respirations and skin colour were the most that could be expected. Death was not infrequent and usually unexplained (1). By the beginning of the twentieth century, reports of fulminant fever and tachycardia (rapid heart rate) during or immediately after anaesthesia often ending in death, were being described with increasing frequency in the medical literature (2-6). As a number of cases from New York had occurred during summer months, they were initially thought to be a form of heat stroke due to overly hot operating theatres (2-6). However, one enterprising anaesthetist (5:' checked the weather reports for the days on which some of these so called "heat strokes" had occurred. He found that on the days i'n question the ambient 0 temperature had never been in excess of 72 F. Environmental heat, therefore, could not have been a cause of at least some of these reactions.

Editors and Affiliations

  • Department of Anaesthesia and Pharmacology, University of Toronto, Toronto, Canada

    Beverley A. Britt

  • Toronto General Hospital, Toronto, Canada

    Beverley A. Britt

Bibliographic Information

  • Book Title: Malignant Hyperthermia

  • Editors: Beverley A. Britt

  • DOI: https://doi.org/10.1007/978-1-4613-2079-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1987

  • Hardcover ISBN: 978-0-89838-960-9Published: 30 September 1987

  • Softcover ISBN: 978-1-4612-9233-3Published: 17 September 2011

  • eBook ISBN: 978-1-4613-2079-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXIV, 420

  • Topics: Anesthesiology, Internal Medicine, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation