Basic and Clinical Aspects of Malignant Melanoma

1. Front Matter

   Pages i-xiv

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2. Basic Biology

   1. Front Matter

      Pages 1-1

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   2. The Role of Oncogenes in the Pathogenesis of Malignant Melanoma

      • Anthony P. Albino

      Pages 3-39

   3. Laminin and Fibronectin Modulate the Metastatic Activity of Melanoma Cells

      • Victor P. Terranova

      Pages 41-60

   4. Structure, Function, and Biosynthesis of Ganglioside Antigens Associated with Human Tumors Derived From the Neuroectoderm

      • Jay M. Rosenberg, David A. Cheresh

      Pages 61-86

3. Natural History

   1. Front Matter

      Pages 87-87

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   2. Epidemiology of Ocular Melanoma

      • Leslie Hyman, M. Cristina Leske, Anthony P. Polednak

      Pages 89-117

   3. Malignant Melanoma: Prognostic Factors

      • Terence J. Harrist, Calvin L. Day Jr.

      Pages 119-130

   4. Endocrine Influences on the Natural History of Human Malignant Melanoma

      • Larry Nathanson, Gajanan A. Kulkarni

      Pages 131-139

   5. Psychosocial Factors Associated with Prognostic Indicators, Progression, Psychophysiology, and Tumor-host Response in Cutaneous Malignant Melanoma

      • Ralph J. DiClemente, Lydia Temoshok

      Pages 141-154

   6. Central nervous system metastases in malignant melanoma

      • William A. Robinson, Kathleen Jobe, Richie Stevens

      Pages 155-163

4. Therapy

   1. Front Matter

      Pages 165-165

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   2. Interferon Trials in the Management of Malignant Melanoma and Other Neoplasms: An Overview

      • E. T. Creagan

      Pages 167-194

   3. The treatment of Malignant Melanoma by Fast Neutrons

      • Peter R. Blake

      Pages 195-213

5. Back Matter

   Pages 215-222

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Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdividions such as lung cancer, genitouri­ nary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

• Staging
• Tumor
• cancer
• cancer treatment
• diagnosis
• interferon
• melanoma
• metastasis
• oncology
• pathogenesis
• Diagnostic Radiology

• School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, USA

  Larry Nathanson

• Oncology-Hematology Division, Winthrop University Hospital, Mineola, USA

  Larry Nathanson

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