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Risk/Benefit Analysis for the Use and Approval of Thrombolytic, Antiarrhythmic, and Hypolipidemic Agents

Proceedings of the Ninth Annual Symposium on New Drugs & Devices, October 27 & 28, 1988

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. Joel Morganroth

    1. Likoff Cardiovascular Institute of Hahnemann Medical College and Hospital, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. E. Neil Moore

    1. School of Veterinary Medicine, University of Pennsylvania, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 100)

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Table of contents (17 papers)

  1. Front Matter

    Pages i-xvi
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  3. Back Matter

    Pages 59-89
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  5. Back Matter

    Pages 117-142
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  7. Back Matter

    Pages 167-198
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  8. Hypolipidemic Agents: Clinical & Regulatory Issues

    1. Front Matter

      Pages 199-199
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    2. What are the Recommendations to the Medical Community to Institute Hypolipidemic Therapy?

      • Joel Morganroth
      Pages 201-214
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Keywords

About this book

The Symposium on New Drugs provides a forum for academic investigators, research and development personnel from the pharmaceutical industry and members of the Food and Drug Administration to discuss important clinical research issues. The Ninth Annual symposium on New Drugs addressed the problem of determining the risk versus benefit for use of three important classes of cardiovascular agents: thrombolytic, antiarrhythmic, and hypolipidemic agents. The use of thrombolytic agents has become one of the major advances in clinical intensive cardiologic care in the 1980s. While the lysis of clot(s) obstructing a major coronary artery should reverse or prevent the damage of acute myocardial ischemia and infarction, one must carefully consider the potential risks of such agents in regards to their potential benefits. The time when a thrombolytic agent should be administered to maximize benefit as well as how one defines a dose response relationship using intravenous critical care medicines were discussed as important clinical trial issues. The benefit versus risk data on currently available thrombolytic agents was reviewed and the potential roles for adjunctive agents addressed. Overall strategies regarding post- x thrombolytic care and relationships to sudden cardiac death were also detailed. The panel discussion sections provided a comprehensive view of the current thinking of the various participating groups in this symposium. Sudden cardiac death remains the number one cause of mortality in western industrialized societies.

Editors and Affiliations

  • Likoff Cardiovascular Institute of Hahnemann Medical College and Hospital, USA

    Joel Morganroth

  • School of Veterinary Medicine, University of Pennsylvania, USA

    E. Neil Moore

Bibliographic Information

  • Book Title: Risk/Benefit Analysis for the Use and Approval of Thrombolytic, Antiarrhythmic, and Hypolipidemic Agents

  • Book Subtitle: Proceedings of the Ninth Annual Symposium on New Drugs & Devices, October 27 & 28, 1988

  • Editors: Joel Morganroth, E. Neil Moore

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-1605-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1989

  • Hardcover ISBN: 978-0-7923-0294-0Published: 30 June 1989

  • Softcover ISBN: 978-1-4612-8888-6Published: 10 October 2011

  • eBook ISBN: 978-1-4613-1605-3Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XVIII, 298

  • Topics: Cardiology

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