What regulation shall we have for the operation? Shall a man transfuse he knows not what. to correct he knows not what. God knows how (l)? Dr. Henry Stubbs Royal College of Physicians circa 1670 If dialysis therapy were a new phannaceutical product being evaluated by the FDA now, it might not be approved for marketing. The recommended dose, its potential toxicity, the side effects of under-or over-dialysis as well as its efficacy have been the subject of very few studies. The high mortality rate associated with the treatment may raise a few eyebrows. That it is a life-saving modality of treatment is undoubtedly true for more than 100,000 patients in the United States and for more than a million patients world wide. Because dialysis has extended the lives of many people by a variable period of time, most nephrologists have "rested on their laurels" and did not vigorously pursue studies to optimize these treatments. But facts have a way of intruding in all our lives and the facts are that the overall mortality rate of dialysis patients in the United States is rising and stands close to 25% per year and is closer to 33% per year for patients between the ages of 65 and 74 (2). These mortality figures are considerably higher for age-adjusted dialysis populations in Europe and particu larly in Japan, and certainly for the age-adjusted nonnal population.

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Authors and Affiliations

University of California, Davis, USA

Thomas A. Depner

Bibliographic Information

Book Title: Prescribing Hemodialysis
Book Subtitle: A Guide to Urea Modeling
Authors: Thomas A. Depner
Series Title: Developments in Nephrology
DOI: https://doi.org/10.1007/978-1-4613-1509-4
Publisher: Springer New York, NY
eBook Packages: Springer Book Archive
Copyright Information: Kluwer Academic Publishers 1991
Hardcover ISBN: 978-0-7923-0833-1Published: 30 November 1990
Softcover ISBN: 978-1-4612-8811-4Published: 26 September 2011
eBook ISBN: 978-1-4613-1509-4Published: 06 December 2012
Edition Number: 1
Number of Pages: XXIV, 292
Topics: Nephrology, Internal Medicine

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Table of contents (10 chapters)

Front Matter

Back Matter

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