Lasers in Cardiovascular Medicine and Surgery: Fundamentals and Techniques

1. Front Matter

   Pages i-xvi

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2. Historical Background

   1. Front Matter

      Pages 1-1

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   2. The History and Development of the Medical Laser

      • Leon Goldman

      Pages 3-7

   3. Historical Background, Development, and Future Trends of Lasers in Cardiovascular Disease

      • George S. Abela

      Pages 9-17

3. Laser Physics in Medical Applications

   1. Front Matter

      Pages 19-19

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   2. Laser Physics and its Relevance to Applications in Medicine

      • Jim Johnson

      Pages 21-30

   3. Laser Sources for Angioplasty

      • Robert F. Bonner, Paul D. Smith, Louis G. Prevosti, Antonio Bartorelli, Yaron Almagor, Martin B. Leon

      Pages 31-44

   4. The Excimer Laser-Tissue Interactions and Early Clinical Results

      • Frank W. Cross, Timothy J. Bowker

      Pages 45-58

   5. Laser Physics and Thermal Properties

      • A. J. Welch, Martin J. C. van Gemert, Wai-Fung Cheong

      Pages 59-71

   6. Thermal Analysis of Laser Ablation of Cardiovascular Tissue

      • Massoud Motamedi, Gerald L. LeCarpentier, Jorge H. Torres, A. J. Welch

      Pages 73-91

   7. Light Distribution, Optical Properties, and Cardiovascular Tissues

      • Martin J. C. van Gemert, A. J. Welch, Steven L. Jacques, Wai-Fung Cheong, Willem M. Star

      Pages 93-110

4. Experimental Studies: Laser-Tissue Interaction, Photodynamic Therapy, Spectroscopy, Electrophysiology

   1. Front Matter

      Pages 111-111

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   2. Immediate and Chronic Effects of Laser Angioplasty

      • George S. Abela

      Pages 113-141

   3. Photosensitizer-Enhanced Laser Angioplasty

      • G. Michael Vincent, George S. Abela, Enrico Barbieri

      Pages 143-152

   4. Laser-Induced Arterial Fluorescence Spectroscopy

      • Lawrence I. Deckelbaum

      Pages 153-165

   5. Laser Balloon Angioplasty: Experimental In-Vivo and In-Vitro Studies

      • J. Richard Spears, I. Nigel Sinclair, Ronald D. Jenkins

      Pages 167-188

   6. Laser Catheter Ablation of Arrhythmias

      • Anne B. Curtis, G. Michael Vincent, George S. Abela

      Pages 189-200

5. Laser Delivery Systems

   1. Front Matter

      Pages 201-201

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   2. Optical Fibers

      • Stephan E. Friedl, Biqing Ye, George S. Abela

      Pages 203-207

   3. Laser Angioplasty with Optically Modified Fiber Tips

      • Cornelius Borst, Rudolf M. Verdaasdonk, Rienk Rienks

      Pages 209-227

Following the advent of percutaneous balloon vel oped and are available for clinical use, as well angioplasty, interventional cardiovascular pro­ as those that are still in investigational phases. cedures have become of great interest to the Clinical case reports are presented by expert in­ cardiologist, radiologist, and cardiovascular vestigators on the use of various catheter systems surgeon. One of the most extensively explored in the coronary and peripheral circulation. alternatives to bypass surgery is laser-mediated Part V (Chapters 17-23) is the most up-to­ angioplasty. The fascination with laser radia­ date review of the clinical experience with vari­ tion has greatly contributed to its popularity, ous laser delivery systems. There is an emphasis but has also burdened it with unrealistic ex­ on patient selection, criteria for lesion choice, pectations. Many commercial laser systems are and follow-up data. A detailed description of available to the clinician and the researcher, laser recanalization techniques is presented for which often makes the choice of a laser system the various systems in the clinical setting.

• Ablation
• Bypass
• atherosclerosis
• cardiovascular
• circulation
• coronary artery disease
• electrophysiology
• ultrasound
• vascular disease
• thoracic surgery

• University of Florida, Gainesville, USA

  George S. Abela

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