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Pathophysiology of Heart Failure

  • Book
  • © 1996

Overview

Editors:
  1. Naranjan S. Dhalla

    1. MRC Group in Experimental Cardiology Division of Cardiovascular Sciences St. Boniface General Hospital Research Centre Faculty of Medicine, University of Manitoba, Winnipeg, Canada

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  2. Pawan K. Singal

    1. MRC Group in Experimental Cardiology Division of Cardiovascular Sciences St. Boniface General Hospital Research Centre Faculty of Medicine, University of Manitoba, Winnipeg, Canada

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  3. Nobuakira Takeda

    1. Department of Internal Medicine Aoto Hospital, Jikei University School of Medicine, Tokyo, Japan

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  4. Robert E. Beamish

    1. MRC Group in Experimental Cardiology Division of Cardiovascular Sciences St. Boniface General Hospital Research Centre Faculty of Medicine, University of Manitoba, Winnipeg, Canada

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Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 168)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xli
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  2. Cardiomyopathy and Contractile Dysfunction

    1. Front Matter

      Pages 1-1
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    2. Experimental Models of Heart Failure and Cardiomyopathy

      • Gordon W. Moe, Paul W. Armstrong
      Pages 3-8

    3. Role of Tissue and Circulating Substance P in Cardiovascular Injury Associated with Mg-Deficiency

      • William B. Weglicki, Benjamin F. Dickens, I. Tong Mak, Jay H. Kramer, Richard E. Stafford, Marie M. Cassidy et al.
      Pages 9-19

    4. Functional and Metabolic Effects of Norepinephrine on the Rat Heart

      • Heinz-Gerd Zimmer
      Pages 21-29

    5. Interventions in Experimentally Induced Diabetic Cardiomyopathy

      • John H. McNeill, Margaret C. Cam, Nandakumar Sambandam, Brian Rodrigues
      Pages 31-45

    6. Diabetes as a Risk Factor for Cardiovascular Disease: Experimental Models

      • Leonard S. Golfman, Robert E. Beamish, Naranjan S. Dhalla
      Pages 47-75

    7. Ethanol-Induced Hypertension: The Role of Acetaldehyde

      • Sudesh Vasdev, Brendan Barrett, Linda Longerich, Carol Ann Ford
      Pages 77-93

    8. Abnormalities in Cardiac Contractile Proteins and Cardiac Dysfunction

      • Ashwani Malhotra, Anthony J. Straceski, M. Cecilia Lopez, Antonio Nakouzi
      Pages 95-108

    9. Role of the Slow Sodium Channel in Hereditary Cardiomyopathy

      • Ghassan Bkaily, Gaétan Jasmin, Danielle Jacques, Libuse Proschek
      Pages 109-125

    10. Cardiac Contractile Failure Caused by Disturbances in Myofibrillar Energy Supply and Pathogenesis of Cardiomyopathies

      • Valeri I. Kapelko, Mikhail I. Popovich, Valerian V. Kupriyanov
      Pages 127-138

    11. Changes in Contractile Proteins under Oxidative Stress

      • Masanori Kaneko, Yuji Matsumoto
      Pages 139-147

    12. Antioxidants and the Heart

      • Pawan K. Singal, Arvinder K. Dhalla, Neelam Khaper, Michael Hill, Thomas P. Thomas, Charita Seneviratne
      Pages 149-170

    13. Gene Expression of Cardiac Myocytes: A Pharmacologic Target for the Failing Heart?

      • Heinz Rupp, Marian Turcani, Bernhard Maisch, Christian G. Brilla
      Pages 171-188

  3. Calcium-Related Events and Heart Dysfunction

    1. Front Matter

      Pages 189-189
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    2. Regulation of Slow Ca2+ Channels of Myocardial Cells by Cyclic Nucleotides and Phosporylation

      • Nicholas Sperelakis, Kotaro Sumii
      Pages 191-223

    3. Multiple Roles for the Membrane-Associated Ca2+/Calmodulin-Dependent Protein Kinase in the Regulation of Sarcoplasmic Reticulum Function in Heart Muscle

      • Njanoor Narayanan
      Pages 225-243

    4. Calreticulin, a Multifunctional Ca2+ Binding Protein of Smooth Muscle Sarcoplasmic Reticulum Membranes

      • Nasrin Mesaeli, Michal Opas, Marek Michalak
      Pages 245-251

    5. Intracellular Ca2+ Transients in Response to Step Length Changes in Aequorin-Injected Ferret Papillary Muscles

      • Satoshi Kurihara, Kimiaki Komukai, Makoto Kawai, Etsuko Tanaka, Masato Konishi
      Pages 253-261

    6. Initial Changes in β-Adrenergic Receptor Function during Development of Rapid Ventricular Pacing-Induced Heart Failure

      • Dorothy E. Vatner, Kaname Kiuchi, Richard P. Shannon, Stephen F. Vatner
      Pages 263-276
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Keywords

About this book

Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment.
Audience: Clinical and experimental cardiologists will find the book a helpful source of ideas and inspiration.

Editors and Affiliations

  • MRC Group in Experimental Cardiology Division of Cardiovascular Sciences St. Boniface General Hospital Research Centre Faculty of Medicine, University of Manitoba, Winnipeg, Canada

    Naranjan S. Dhalla, Pawan K. Singal, Robert E. Beamish

  • Department of Internal Medicine Aoto Hospital, Jikei University School of Medicine, Tokyo, Japan

    Nobuakira Takeda

Bibliographic Information

  • Book Title: Pathophysiology of Heart Failure

  • Editors: Naranjan S. Dhalla, Pawan K. Singal, Nobuakira Takeda, Robert E. Beamish

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-1235-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1996

  • Hardcover ISBN: 978-0-7923-3571-9Published: 31 December 1995

  • Softcover ISBN: 978-1-4612-8525-0Published: 17 September 2011

  • eBook ISBN: 978-1-4613-1235-2Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XLII, 578

  • Topics: Cardiology

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