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Endothelial Cell Biology in Health and Disease

  • Book
  • © 1988

Overview

Editors:
  1. Nicolae Simionescu

    1. Institute of Cellular Biology and Pathology, Bucharest, Romania

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    You can also search for this editor in PubMed   Google Scholar

  2. Maya Simionescu

    1. Institute of Cellular Biology and Pathology, Bucharest, Romania

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xix
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  2. Structure—Function Correlations in Endothelial Cells

    1. Front Matter

      Pages 1-1
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    2. The Microvascular Endothelium Revisited

      • G. E. Palade
      Pages 3-22

    3. Ultrastructural Studies of Capillary Endothelium

      • Roger C. Wagner
      Pages 23-47

  3. Transport Functions of Endothelial Cells

    1. Front Matter

      Pages 49-49
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    2. Transport Pathways and Processes

      • Eugene M. Renkin
      Pages 51-68

    3. Receptor-Mediated Transcytosis of Plasma Molecules by Vascular Endothelium

      • Maya Simionescu
      Pages 69-104

    4. Studies of Pulmonary Endothelial Permeability Using Tritiated Dextrans

      • John H. Hansen-Flaschen, Alfred P. Fishman
      Pages 105-120

  4. Endothelial Cell Growth and Differentiation

    1. Front Matter

      Pages 121-121
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    2. Endothelial Morphogenesis

      • Ronald L. Heimark, Stephen M. Schwartz
      Pages 123-143

  5. Endothelial Cytoskeleton and Matrix and Their Interactions

    1. Front Matter

      Pages 145-145
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    2. The Endothelial Junction

      • Werner W. Franke, Pamela Cowin, Christine Grund, Caecilia Kuhn, Hans-Peter Kapprell
      Pages 147-166

    3. Endothelial Cell-Extracellular Matrix Interactions

      • Joseph A. Madri, Bruce M. Pratt, Judith Yannariello-Brown
      Pages 167-188

  6. Endothelial Cell Anticoagulant and Fibrinolytic Activities

    1. Front Matter

      Pages 189-189
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    2. Assembly and Function of the Protein C Anticoagulant Pathway on Endothelium

      • Charles T. Esmon
      Pages 191-206

    3. The Biochemistry and Physiology of Anticoagulantly Active Heparin-like Molecules

      • James A. Marcum, Robert D. Rosenberg
      Pages 207-228

    4. The Fibrinolytic System of Cultured Endothelial Cells

      • Scott A. Curriden, Thomas J. Podor, David J. Loskutoff
      Pages 229-252

  7. Endothelial Cell Procoagulant Activity

    1. Front Matter

      Pages 253-253
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    2. Vascular Endothelium

      • Michael A. Gimbrone Jr., Michael P. Bevilacqua
      Pages 255-273

    3. Endothelium and the Regulation of Coagulation

      • David M. Stern, Dean A. Handley, Peter P. Nawroth
      Pages 275-306
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Keywords

About this book

Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated. Beginning with the middle of the 19th cen­ tury, our knowledge of the histological organization of blood vessels has steadily increased. However, the endothelium, which for a long time was considered to be just an inert barrier lining, had been barely explored until three decades ago. Since then, there has been an upsurge of interest in the fine structure and function of endothelial cells. Intense in vivo and in vitro investigations have revealed that the endothelial cell is a key element in a wide variety of normal activities and diseases. A large number of investigators and laboratories have been attracted to endothelial cell research, thus supporting the expansion of the continuously grow­ ing and diversifying field of endotheliology. The number of articles published annually on this subject has increased from a few score at the beginning of the 1970s to more than a thousand in recent years, and an increasing number of journals, books, societies, and symposia focused primarily on the vascular en­ dothelium have marked the last decade.

Editors and Affiliations

  • Institute of Cellular Biology and Pathology, Bucharest, Romania

    Nicolae Simionescu, Maya Simionescu

Bibliographic Information

  • Book Title: Endothelial Cell Biology in Health and Disease

  • Editors: Nicolae Simionescu, Maya Simionescu

  • DOI: https://doi.org/10.1007/978-1-4613-0937-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1988

  • Softcover ISBN: 978-1-4612-8254-9Published: 10 December 2011

  • eBook ISBN: 978-1-4613-0937-6Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XX, 478

  • Number of Illustrations: 103 b/w illustrations

  • Topics: Cell Biology, Cardiology, Animal Anatomy / Morphology / Histology, Plant Sciences

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