Liver Cancer

1. Front Matter

   Pages i-xvi

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2. Pathology and Natural History

   1. Front Matter

      Pages 1-1

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   2. Pathology of Liver Tumors

      • Zachary D. Goodman, Kamal G. Ishak

      Pages 3-19

   3. Natural History of Liver Cancer

      • Geoffrey Falkson, Buks Coetzer

      Pages 21-31

3. Diagnosis of Liver Cancer

   1. Front Matter

      Pages 33-33

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   2. Radiologic Techniques for Detection and Evaluation of Liver Cancer

      • Errol Lewis, Sidney Wallace

      Pages 35-67

   3. Nuclear Medicine Aspects of Primary and Secondary Liver Cancer

      • Jerry W. Froelich, James H. Thrall, Dennis P. Swanson

      Pages 69-83

4. Surgery in Liver Cancer

   1. Front Matter

      Pages 85-85

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   2. Surgical Anatomy of the Liver and Biliary Tree

      • David M. Nagorney, Jonathan A. Van Heerden

      Pages 87-98

   3. Surgical Therapy of Liver Cancer

      • Reyer T. Ottow, David A. August, Paul H. Sugarbaker

      Pages 99-142

   4. Hepatic Artery Ligation for Liver Cancer

      • Nicholas J. Petrelli, Arnold Mittelman

      Pages 143-156

   5. Hepatic Artery Embolization for Liver Cancer

      • Chusilp Charnsangavej, Sidney Wallace, C. Humberto Carrasco, William Bechtel

      Pages 157-177

   6. Surgical Aspects of Intrahepatic Artery Therapy

      • John E. Niederhuber

      Pages 179-194

5. Chemotherapy of Liver Cancer

   1. Front Matter

      Pages 195-195

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   2. Chemotherapy of Liver Cancer

      • Jacob J. Lokich

      Pages 197-215

   3. New Chemotherapeutic Agents in Liver Cancer

      • Franco M. Muggia, Michael D. Green

      Pages 217-224

   4. Intraperitoneal Chemotherapy: A Possible Role in the Treatment of Hepatic Metastases

      • James L. Speyer

      Pages 225-235

   5. Pharmacologic Studies of Hepatic Intra-Arterial Chemotherapy

      • William D. Ensminger, John W. Gyves

      Pages 237-245

   6. Regional Chemotherapy of Liver Cancer

      • Richard W. Opfell, Joseph Bowen

      Pages 247-261

   7. Regional Arterial Therapy in the Management of Primary Liver Neoplasms

      • Yehuda Z. Patt, Chusilp Charnsangavej, Marilyn Soski, Giora M. Mavligit

      Pages 263-273

Neoplastic disease confined to the liver is an important worldwide problem. In the industrialized nations, metastatic disease of the most common cancers involves the liver in upwards of 50% of cases. Primary hepatic tumors are virtually epidemic in most third world countries and certainly constitute one of the ten most common causes of cancer deaths on a worldwide scale. Amazingly, little specific attention has been devoted to therapeutic approaches of liver and biliary tumors until recently. We attribute this apparent lack of interest to the uniformly poor progno­ sis of patients so afflicted, and attribute the renewed interest to the exciting new developments in diagnostic and therapeutic technology as well as in tumor biology. The purpose of this book is to collect in one volume an integrated selection of articles that would provide the therapist with a comprehensive, yet practical, overview of liver cancer. We believe the contributors to the book are superbly qualified experts on the various subjects and provide in-depth information on respective fields. The edit­ ing process for us was not only educational but thrilling as the high quality and complementary nature of the chapters became evident as we received them. Be­ cause many areas in the field of liver cancer are controversial, the reader will notice that contradictory opinions are presented by some of the authors.

• adjuvant therapy
• liver
• liver tumor
• metastasis
• metastatic disease
• pathology
• prevention
• surgery
• tumor

• Rita and Stanley H. Kaplan Cancer Center, New York University Medical Center, New York, USA

  Joseph C. Bottino, Franco M. Muggia

• Clinical Oncology Program, University of California,Irvine Medical Center, Orange, USA

  Richard W. Opfell

Policies and ethics