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RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding

Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10–14, 1984

  • Conference proceedings
  • © 1985

Overview

Editors:
  1. Philip Furmanski

    1. AMC Cancer Research Center, Denver, USA

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  2. Jean Carol Hager

    1. AMC Cancer Research Center, Denver, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Marvin A. Rich

    1. AMC Cancer Research Center, Denver, USA

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Part of the book series: Developments in Oncology (DION, volume 28)

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Table of contents (31 papers)

  1. Front Matter

    Pages i-xxi
    Download chapter PDF

  2. Molecular Genetics of the RNA Tumor Viruses

    1. Myc, a Genetic Element that is Shared by a Cellular Gene (proto-myc) and by viruses with one (MC29) or two (MH2) onc genes

      • T. S. Papas, N. C. Kan, D. K. Watson, J. A. Lautenberger, C. Flordellis, K. P. Samuel et al.
      Pages 1-13

    2. Viral and Cellular Fos Gene

      • I. M. Verma, T. Curran, A. D. Miller, C. Van Beveren
      Pages 14-24

    3. P21 ras Transforming Protein: Significance of the Carboxy Terminus

      • Berthe M. Willumsen, Douglas R. Lowy
      Pages 25-40

    4. Protein Phosphorylation at Tyrosine in Normal and Transformed Cells

      • Jonathan A. Cooper, Kathy Gould, Tony Hunter
      Pages 41-53

    5. Activation of a Gene Coding for a Normal Human Growth Factor to One with Transforming Properties

      • Stuart A. Aaronson, Keith C. Robbins
      Pages 54-66

    6. Cell Cycle Control of C-Myc Expression

      • Kathleen Kelly, Brent Cochran, Charles Stiles, Philip Leder
      Pages 67-75

  3. Endogenous Retrovirus Sequences in Human Cells

    1. A New Class of Human Endogenous Retroviral Genes

      • Robert Callahan, Ing-Ming Chiu, Toby Horn, Igbal Ali, Joan Robbins, Stuart Aaronson et al.
      Pages 76-92

    2. Structure and Function of Human Endogenous Type C Retroviral DNAs

      • A. B. Rabson, P. E. Steele, R. Repaske, M. A. Martin
      Pages 93-107

    3. ERV3, A Full-Length Human Endogenous Provirus: Sequence Analysis and Evolutionary Relationships

      • Catherine D. O’Connell, Maurice Cohen
      Pages 108-115

  4. Molecular Biology of Human Cancers

    1. Molecular Basis of Human B Cell Neoplasia

      • Carlo M. Croce, Peter C. Nowell
      Pages 116-126

    2. Stage Specific Transforming Genes in Lymphoid Neoplasms

      • M. A. Lane, H. A. F. Stephens, M. B. Tobin, Kevin Doherty
      Pages 127-132

    3. Oncogenes Involved in Chronic Myelocytic Leukemia

      • Nora Heisterkamp, John R. Stephenson, Gerard Grosveld, Annelies De Klein, John Groffen
      Pages 133-150

    4. Monoclonal Antibodies Generated to a Synthetic Peptide Define Ras Gene Expression at the Single Cell Level in Human Colon and Mammary Carcinomas

      • A. Thor, P. Horan Hand, D. Wunderlich, M. Weeks, A. Caruso, R. Muraro et al.
      Pages 151-167

    5. Which Cancers are Caused by Activated Proto-Onc Genes?

      • Peter H. Duesberg, Michael Nunn, Nancy Kan, Dennis Watson, Peter H. Seeburg, Takis Papas
      Pages 168-190

  5. HTLV/LAV, T-Cell Leukemia and AIDS

    1. The Family of Human T-Cell Leukemia Viruses and Their Role in the Cause of T-Cell Leukemia and AIDS

      • R. C. Gallo, G. Shaw, B. Hahn, F. Wong-Staal, M. Popovic, J. Schupbach et al.
      Pages 191-205

    2. A Novel Human Lymphotropic Retrovirus (LAV): New Data on Its Biology and Role in AIDS

      • L. Montagnier, F. Barre-Sinoussi, D. Klatzmann, J. C. Gluckman, C. Rouzioux, F. Brun-Vezinet et al.
      Pages 206-217

    3. Biology of Human T Cell Leukemia Viruses in Immunosuppression and AIDS

      • M. Essex
      Pages 218-231

    4. Human Retrovirus in Acquired Immunodeficiency Syndrome (AIDS)

      • Donald P. Francis, Cirilo D. Cabradilla, Paul M. Feorino, V. S. Kalyanaraman
      Pages 232-239

    5. Human RNA and DNA Oncogenic Viruses and Their Importance in Transmissible and Malignant Diseases

      • Guy De The
      Pages 240-246
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Keywords

About this book

We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic significance, their role in cancer was proposed and hotly debated. The critical early discoveries, even those made as recently as 25 years ago, were met with rejection; not skepticism or cautious restraint, but outright rejection. During the 60's, there was a gradual acceptance of the association between viruses and cancer, the result of landmark studies in experimental systems, and this led to a frenzy of activity in the field. There followed another period of doubt and uncertainty, due to the difficulty in attempting to apply directly, and in retrospect inappropriately, the tenets of infectious disease to human cancers, only to have the field resurrected, revitalized and redirected by the explosion of progress in molecular biology and genetics.

Editors and Affiliations

  • AMC Cancer Research Center, Denver, USA

    Philip Furmanski, Jean Carol Hager, Marvin A. Rich

Bibliographic Information

  • Book Title: RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding

  • Book Subtitle: Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10–14, 1984

  • Editors: Philip Furmanski, Jean Carol Hager, Marvin A. Rich

  • Series Title: Developments in Oncology

  • DOI: https://doi.org/10.1007/978-1-4613-2583-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1985

  • Hardcover ISBN: 978-0-89838-703-2Published: 31 March 1985

  • Softcover ISBN: 978-1-4612-9620-1Published: 05 October 2011

  • eBook ISBN: 978-1-4613-2583-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXII, 410

  • Topics: Oncology

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