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The Stressed Heart

  • Book
  • © 1987

Overview

Editors:
  1. Marianne J. Legato

    1. Columbia University College of Physicians and Surgeons, USA

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Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 62)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xxi
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  2. Regulation of Gene Expression in the Normal and Overloaded Heart

    • Jean Marie Moalic, Bernard Swynghedauw
    Pages 1-19

  3. Cell Stress and the Initiation of Growth

    • Graeme L. Hammond
    Pages 21-47

  4. Subcellular Growth of Cardiocytes during Hypertrophy

    • Robert J. Tomanek, Craig A. Canby
    Pages 49-65

  5. Capillarity and the Distribution of Capillaries and Mitochondria in Cardiac Growth

    • Natalio Banchero
    Pages 67-86

  6. The Coronary Vasculature During Myocardial Hypertrophy

    • William M. Chilian, Robert J. Tomanek, Melvin L. Marcus
    Pages 87-105

  7. Microcirculation in the Stressed Heart

    • Karel Rakusan
    Pages 107-123

  8. Pathology and Pathophysiology of the Coronary Microcirculation in Myocardial Ischemia

    • Stephen M. Factor
    Pages 125-147

  9. The Biochemistry of Myocardial Failure

    • Louis A. Sordahl, Claude R. Benedict
    Pages 149-168

  10. Force-Interval Relationship and Activator Calcium Availability: Similarities of Sympathetic Stimulation and Hypertrophy and Heart Failure

    • Page A. W. Anderson
    Pages 169-218

  11. Right Atrial Ultrastructure in Coronary Artery Disease: Characterization of Chronic Ischemia

    • John J. Fenoglio Jr., Tuan Duc Pham
    Pages 219-233

  12. Connective Tissue in the Normal and Hypertrophied Heart

    • Thomas F. Robinson
    Pages 235-251

  13. Myocardial Hypertrophy and Cardiac Failure: A Complex Interrelationship

    • Barry M. Massie
    Pages 253-273

  14. The Regression of Cardiac Hypertrophy: Functional, Anatomic, and Hemodynamic Considerations

    • George Cooper IV
    Pages 275-287

  15. Regression of Left Ventricular Hypertrophy: Clinical Considerations

    • Anthony P. Goldman, Morris N. Kotler
    Pages 289-310

  16. The Cardiocyte in Senescence

    • Robert J. Tomanek
    Pages 311-321

  17. Stress and Sudden Death

    • Edward M. Dwyer Jr.
    Pages 323-335

  18. Back Matter

    Pages 337-339
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Keywords

About this book

The Stressed Heart is truly unique in concept and will provide an eXCItmg adventure to the reader no matter what his or her field of expertise and interest. The title, although quite appropriate, does not adequately indicate the range of topics considered or the rational interrelationships among them. Indeed, perhaps the most important point to be learned from the book is that a serious consideration of the response of the heart to mechanical overload, ischemia, or excessive humoral stimuli must include evaluation of each of the topics in the table of contents. The heart responds to stress through alterations in both structure and function. How these changes are brought about is the subject of the initial chapters. These consider first the normal regulation of gene expression in the heart, the rapid response to mechanical overload that leads to both quantitative and qualitative changes in the contractile proteins, and our current understand­ ing of the signals that might be elicited by stress and alter gene expression. One chapter emphasizes the fact that, regardless of the nature of the stress, the common denominator is a discrepancy between energy requirements and expenditure. The central role of cellular acidosis in initiating the sequence of responses to stress and the possible roles of peptide regulators of transcription and protein regulators of translation are considered in detail.

Editors and Affiliations

  • Columbia University College of Physicians and Surgeons, USA

    Marianne J. Legato

Bibliographic Information

  • Book Title: The Stressed Heart

  • Editors: Marianne J. Legato

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-2041-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1987

  • Hardcover ISBN: 978-0-89838-849-7Published: 31 May 1987

  • Softcover ISBN: 978-1-4612-9214-2Published: 14 October 2011

  • eBook ISBN: 978-1-4613-2041-8Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XXII, 340

  • Topics: Cardiology

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