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Model Systems of Development and Aging of the Nervous System

  • Book
  • © 1987

Overview

Editors:
  1. Antonia Vernadakis

    1. Departments of Psychiatry and Pharmacology, University of Colorado School of Medicine, Denver, USA

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  2. Alain Privat

    1. Neurobiologie du Développement, INSERM U249, Montpellier Cedex, France

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  3. Jean M. Lauder

    1. Department of Anatomy, University of North Carolina School of Medicine, Chapel Hill, USA

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  4. Paola S. Timiras

    1. Department of Physiology-Anatomy, University of California, Berkeley, USA

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  5. Ezio Giacobini

    1. Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, USA

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Neurons, Neuroglia and Neuronal-Glial Interactions

    1. Front Matter

      Pages 1-1
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    2. Cell Culture Systems for Purified Retinal Neurons and Photoreceptors

      • Ruben Adler
      Pages 3-17

    3. Primary Cultures of Gabaergic and Glutamatergic Neurons as Model Systems to Study Neurotransmitter Functions I. Differentiated Cells

      • Leif Hertz, Arne Schousboe
      Pages 19-31

    4. Primary Cultures of GABaergic and Glutamatergic Neurons as Model Systems to Study Neurotransmitter Functions II. Developmental Aspects

      • Arne Schousboe, Leif Hertz
      Pages 33-42

    5. Development of Cerebral Cortical GABaergic Neurons In Vitro

      • Kinya Kuriyama, Seitaro Ohkuma
      Pages 43-56

    6. Morphological Analysis of 5-HT Neurons Transplanted into the Olfactory Bulb of the Adult Rat

      • Alain Privat, Hussein Mansour, Michel Geffard
      Pages 57-73

    7. An Analysis of Interactions Between Grafted Serotonin Neurons And An Adult Host Hippocampus

      • Menahem Segal
      Pages 75-84

    8. Neuronal Modulation by Number and by Volume: A Review and Critical Analysis

      • Guido Filogamo
      Pages 85-100

    9. Oligodendrocyte Development: Immunological Studies

      • Nicholas W. Seeds, Janet M. Collins, Susan C. Haffke, Dessie Fafoutis
      Pages 101-113

    10. Intracerebral Transplantation as a Model for Studying the Myelination Process

      • Madeleine Gumpel, François Lachapelle, Michel Baulac, Annick Baron-Van Evercooren, Annie Gansmuller, Claude Jacque et al.
      Pages 115-124

    11. In Vitro Effects of Glia Maturation Factor on Bipotential Glial Progenitor Cells

      • E. Peter Bosch, José G. Assouline, Ramon Lim
      Pages 125-137

    12. Specialized Junctions of Glial Cells In Situ and In Vitro

      • Enrico Mugnaini, Paul T. Massa, Sara Szuchet
      Pages 139-170

    13. Electrophysiological and Ionic Transport Properties of Glial Cells in Culture

      • H. Steve White, Dixon M. Woodbury
      Pages 172-191

    14. In Vitro Regulation of Dopaminergic Maturation

      • Alain Prochiantz
      Pages 193-200

    15. Do Mouse Cerebellum Astrocytes Play a Role in Neuronal Survival and Differentiation?

      • Bernard Pessac, Françoise Alliot
      Pages 201-208

    16. Proliferation and Maturation of Rat Neuroblasts in Culture: Influence of Meningeal Cells

      • Claire Gensburger, Gérard Labourdette, Monique Sensenbrenner
      Pages 209-216

  3. Neuromodulation, Synapse and Receptors

    1. Front Matter

      Pages 217-217
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    2. Neurotransmitters as Morphogenetic Signals and Trophic Factors

      • Jean M. Lauder
      Pages 219-237

    3. Multifunctional Roles for Neurotransmitters: The Regulation of Neurite Outgrowth, Growth-Cone Motility and Synaptogenesis

      • Stanley B. Kater, Philip G. Haydon
      Pages 239-255
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Keywords

About this book

The last decade has generated a multitude of studies using in vitro model systems to explore growth and differentiation of the nervous system. Although the findings have been exciting and have revealed unique properties of neural cells, considerable concern continues to be expressed regarding the significance of in vitro findings in terms of their applicability to in vivo biological events. To examine this issue further, a group of scientists pre­ sented and discussed their findings at a conference sponsored by the Institute of Developmental Neuroscience and Aging held in Crete, Greece, 26-29 May 1985. The conference was cosponsored by the University of Crete and was generously supported by the Ministry of Research and Technology of Greece, Tourism Organization of Greece, and also Sandoz and FIDIA. The Directors of the Institute of Developmental Neuroscience and Aging are indebted to these Institutions for their support. For the success of this conference, the Directors owe much to Drs. Eleni Fleischer-Lambropoulos and Yiannis Tsouderos, who spent countless hours in making arrangements so that the participants would have not only a scientific, but also a unique cultural, experience. Several chapters of this book focus on the complex phenomena of neurogenesis and gliogenesis, and the modulation of neuronal differentiation. The concept that neuronal differentiation has both genetic and epigenetic components is documented by elegant studies using both in vitro cultured cells and neurons transplanted in vivo.

Editors and Affiliations

  • Departments of Psychiatry and Pharmacology, University of Colorado School of Medicine, Denver, USA

    Antonia Vernadakis

  • Neurobiologie du Développement, INSERM U249, Montpellier Cedex, France

    Alain Privat

  • Department of Anatomy, University of North Carolina School of Medicine, Chapel Hill, USA

    Jean M. Lauder

  • Department of Physiology-Anatomy, University of California, Berkeley, USA

    Paola S. Timiras

  • Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, USA

    Ezio Giacobini

Bibliographic Information

  • Book Title: Model Systems of Development and Aging of the Nervous System

  • Editors: Antonia Vernadakis, Alain Privat, Jean M. Lauder, Paola S. Timiras, Ezio Giacobini

  • DOI: https://doi.org/10.1007/978-1-4613-2037-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1987

  • Hardcover ISBN: 978-0-89838-838-1Published: 31 July 1987

  • Softcover ISBN: 978-1-4612-9212-8Published: 14 October 2011

  • eBook ISBN: 978-1-4613-2037-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 516

  • Topics: Neurosciences

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