Clinical Light Damage to the Eye

1. Front Matter

   Pages i-xi

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2. The Nature of Light and of Light Damage to Biological Tissues

   1. Front Matter

      Pages 1-1

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   2. Radiation, Light, and Sight

      • Louis Erhardt, David Miller

      Pages 3-15

   3. The Photochemistry of Life and Cell Death: A Philosophical Overview

      • David Miller

      Pages 17-31

3. Light Damage to the Eye

   1. Front Matter

      Pages 33-33

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   2. Perspective on Damage to Angle Structures

      • P. John Anderson, David L. Epstein

      Pages 35-53

   3. Light and the Cornea and Conjunctiva

      • David Miller

      Pages 55-63

   4. Light Damage to the Lens

      • Seymour Zigman

      Pages 65-78

   5. Phototoxic Changes in the Retina

      • John Weiter

      Pages 79-125

   6. Light-Induced Changes in the Skin of the Lid

      • Jeffrey D. Bernhard

      Pages 127-144

4. Protecting the Eye from Light Damage

   1. Front Matter

      Pages 145-145

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   2. Ultraviolet-Absorbing Intraocular Lens Implants

      • David Miller

      Pages 147-164

   3. Approaches to Protection Against Light-Induced Changes in the Eye

      • David Miller, Robert Stegmann

      Pages 165-179

5. Overview of Light Damage to the Eye

   1. Front Matter

      Pages 181-181

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   2. Light-Induced Changes in Ocular Tissues

      • Sidney Lerman

      Pages 183-215

6. Back Matter

   Pages 217-225

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To my mind, the superoxide radical discovered by Linus Pauling more than 50 years ago is about to become a major issue in Ameri­ can medicine. Uncannily, Pauling's early focus on vitamin C has pointed the way to the whole catalogue of free-radical scavengers, which we in medicine will be using in the coming decade. In ophthalmology, the basic scientists have been talking about the role of free-radical induction by light for some time. They have accumulated an increasing amount of evidence supporting the idea that prolonged light exposure contributes to cataract development and retinal degeneration. Through Clinical Light Damage to the Eye, we hope to bring this message to the practicing ophthalmolo­ gist. Because Dr. Pauling's work bears so strongly on the key issue of free-radical damage, and because of my own great respect for him as a scientist and a man of rare courage, I invited Dr. Pauling to write the foreword to Clinical Light Damage to the Eye, which follows.

• cell
• eye
• ophthalmology
• retina
• tissue

• Harvard Medical School, USA

  David Miller

• Beth Israel Hospital, Boston, USA

  David Miller

Policies and ethics