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  • Book
  • © 1987

Immunological Approaches to the Diagnosis and Therapy of Breast Cancer

Editors:

  1. Roberto L. Ceriani

    1. John Muir Cancer and Aging Research Institute, Walnut Creek, USA

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-x
    PDF

  2. Sessions I and II

    1. Front Matter

      Pages 1-1
      PDF

    3. A Multiparametric Study by Monoclonal Antibodies in Breast Cancer

      • M. I. Colnaghi, S. Ménard, M. G. Da Dalt, R. Agresti, G. Cattoretti, S. Andreola et al.
      Pages 21-32

    4. Molecular and Immunological Analysis of Mucin Molecules Produced by Normal and Malignant Human Mammary Epithelial Cells

      • Sandra Gendler, Joy Burchell, Andrew B. Griffiths, Joyce Taylor-Papadimitriou
      Pages 33-40

    5. Single Cell Heterogeneity in Breast Cancer

      • Jerry A. Peterson
      Pages 41-53

    6. Monoclonal Antibody Studies of Drug Resistance

      • William L. McGuire, Suzanne A. W. Fuqua, Lynn G. Dressler
      Pages 55-61

  3. Session III

    1. Front Matter

      Pages 83-83
      PDF

    2. Detection and Assay of the 52K Estrogen-Regulated Protease in Mammary Tumors

      • H. Rochefort, V. Cavailles, G. Freiss, D. Derocq, G. Salazar, T. Maudelonde et al.
      Pages 85-94

    6. Heterogeneity vs. Asynchrony of Receptor Expression in Breast Cancer as Determined by Monoclonal Antibodies

      • L. B. Kinsel, J. L. Flowers, J. Konrath, G. S. Leight, G. L. Greene, K. S. McCarty
      Pages 145-156

    7. Immunoaffinity Purification and Structural Analysis of Human Breast Cancer Progesterone Receptors

      • Dean P. Edwards, Patricia A. Estes, Dorraya El-Ashry, Eric Suba, Janet Lawler-Heavner
      Pages 157-168

  4. Session IV

    1. Front Matter

      Pages 169-169
      PDF

    2. Analysis of the Humoral Immune Repertoire in Patients with Cancer

      • Richard J. Cote, Donna M. Morrissey, Alan N. Houghton, Herbert F. Oettgen, Lloyd J. Old
      Pages 171-186

    3. An Improved Method for the Radiohalogenation of Monoclonal Antibodies

      • Michael R. Zalutsky, Acharan S. Narula
      Pages 187-203

    4. Studies on a Epithelial/Epithelial Malignancy Associated Antigen Associated with Human Adenocarcinomas

      • T. F. Bumol, J. Parrish, S. V. DeHerdt, M. E. Spearman, R. Pohland, M. J. Borowitz et al.
      Pages 205-215
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About this book

Once again we have gathered to discover and evaluate advances made in our ability to understand. diagnose and possibly treat breast cancer with the new reagents provided by monoclonal antibody techniques. In the last two years since our first International Workshop on Monoclonal Antibodies and Breast Cancer there has been an enormous surge in the number and quality of applications for these new reagents. Solid achievements have been made in identification and quantitation of estrogen and progesterone receptors. in histopathological diagnostic procedures. in serum diagnosis. and we are witnessing now the first attempts to treat breast cancer with immunoconjugates. Cytosolic estrogen receptors can now be quantitated with monoclonal antibodies. and also their cellular distribution can be directly assessed histologically. In addition. monoclonal antibodies to progesterone receptors have been generated that show promise in having similar uses as those to the estrogen receptor. In the field of diagnosis. the use of monoclonal antibodies has permitted the development of serological approaches for early diagnosis by identifying and measuring breast epithelial antigens in serum. and of histological approaches for establishing criteria for breast cancer dissemination and prognosis. With great expectations we are all following developments in the area of breast cancer treatment using conjugates of anti-breast epithelial monoclonal antibodies which are now confirming earlier reports in affecting breast tumor control. The recent creation of newer monoclonal antibodies and conjugates await experimentation and clinical trials to determine their value.
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Keywords

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Editors and Affiliations

  • John Muir Cancer and Aging Research Institute, Walnut Creek, USA

    Roberto L. Ceriani

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Bibliographic Information

  • Book Title: Immunological Approaches to the Diagnosis and Therapy of Breast Cancer

  • Editors: Roberto L. Ceriani

  • DOI: https://doi.org/10.1007/978-1-4613-1903-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1987

  • Softcover ISBN: 978-1-4612-9059-9Published: 19 October 2011

  • eBook ISBN: 978-1-4613-1903-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 282

  • Topics: Oncology

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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