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The Molecular Immunology of Complex Carbohydrates

  • Book
  • © 1988

Overview

Editors:
  1. Albert M. Wu

    1. Texas Agricultural Experimental Station, Texas A&M University, College Station, USA

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  2. L. Garry Adams

    1. Texas Agricultural Experimental Station, Texas A&M University, College Station, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 228)

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Table of contents (37 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Antibody Specificity, Epitope and Lectinology

    1. Antibody Combining Sites: How Much of the Antibody Repertoire are we Seeing? How does it Influence Our Understanding of the Structural and Genetic Basis of Antibody Complimentarity?

      • Elvin A. Kabat
      Pages 1-45

    2. Sialic Acids as Antigenic Determinants of Complex Carbohydrates

      • Roland Schauer
      Pages 47-72

    3. Blood Group Active Haptens in Urine and Faeces

      • Arne Lundblad, M. Alan Chester
      Pages 73-81

    4. The Separation of Immunocyte Subpopulations by Use of Various Lectins

      • Toshiaki Osawa
      Pages 83-104

    5. Mannose-Binding Proteins of Animal Origin

      • Y. C. Lee
      Pages 105-121

    6. Sialic Acid and N-Acetylgalactosamine Specific Bacterial Lectins of Enterotoxigenic Escherichia Coli (ETEC)

      • Mats Lindahl, Reinhard Brossmer, Torkel Wadström
      Pages 123-152

    7. Interaction of Viruses, Bacteria and Bacterial Toxins with Host Cell Surface Glycolipids. Aspects on Receptor Identification and Dissection of Binding Epitopes

      • Klaus Bock, Karl-Anders Karlsson, Nicklas Strömberg, Susann Teneberg
      Pages 153-186

    8. Membrane Glycoproteins and Plant and Animal Proteins with Lectin or Lectin-Like Properties

      • Zhao-Wen Shen
      Pages 187-203

    9. Differential Binding Properties of GalNAc and/or Gal Specific Lectins

      • Albert M. Wu, Shunji Sugii
      Pages 205-263

  3. Complex Carbohydrates as Antigens

    1. Antigenic Properties of Human Erythrocyte Glycophorins

      • Elwira Lisowska
      Pages 265-315

    2. Carbohydrate Structures as ONCO-Developmental Antigens and Components of Receptor Systems

      • Ten Feizi
      Pages 317-329

    3. Chemistry of Human Erythrocyte Polylactosamine Glycopeptides (Erythroglycans) as Related to ABH Blood Group Antigenic Determinants

      • Roger A. Laine, Jeffrey S. Rush
      Pages 331-347

    4. Blood Group Antigens and the Enzymes Involved in their Synthesis: Past and Present

      • W. M. Watkins
      Pages 349-350

    5. Structural Concepts of the Human Blood Group A, B, H, Lea, Leb, I and i Active Glycoproteins Purified from Human Ovarian Cyst Fluid

      • Albert M. Wu
      Pages 351-394

    6. Biochemistry and Lectin Binding Properties of Mammalian Salivary Mucous Glycoproteins

      • Anthony Herp, Carol Borelli, Albert M. Wu
      Pages 395-435

    7. New Trends in Ganglioside Chemistry

      • Sandro Sonnino, Riccardo Ghidoni, Giuliano Gazzotti, Domenico Acquotti, Guido Tettamanti
      Pages 437-464

    8. Structural Aspects of Blood Group Glycosphingolipids in the Gastrointestinal Tract

      • Gunnar C. Hansson
      Pages 465-494

    9. Chemically Modified Capsular Polysaccharides as Vaccines

      • H. J. Jennings
      Pages 495-550

    10. Structural and Immunochemical Aspects of Brucella Abortus Endotoxins

      • Albert M. Wu, Neil E. MacKenzie, L. Garry Adams, Roberta Pugh
      Pages 551-576
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Keywords

About this book

During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory molecular interactions such as interaction of complex carbohydrate with hormones or hepatic lectins. The carbohydrate side chains of many complex carbohydrates play essential roles as antigenic determinants b of human blood group ABH, Lea, Le , I, and i activities, as the Forssman specific determinant, and as tumor associated antigenic determinants. Prompted by these and other advances in the field, a Symposium on Molecular Immunology of Complex Carbohydrates was organized as a satellite meeting of the 8th International Glycoconjugate Conference held on September 8- 13, 1985, in Houston, Texas, U. S . A. Many eminent scientists contributed their knowledge at this meeting. The lecture and poster materials of the symposium are contained in this proceeding book, which is divided into four Sections and one Appendix. Section I is entitled Antibody Specificity, Epitope, and Lectinology. Dr. Elvin A.

Editors and Affiliations

  • Texas Agricultural Experimental Station, Texas A&M University, College Station, USA

    Albert M. Wu, L. Garry Adams

Bibliographic Information

  • Book Title: The Molecular Immunology of Complex Carbohydrates

  • Editors: Albert M. Wu, L. Garry Adams

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4613-1663-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1988

  • Hardcover ISBN: 978-0-306-42818-0Published: 01 July 1988

  • Softcover ISBN: 978-1-4612-8923-4Published: 04 October 2011

  • eBook ISBN: 978-1-4613-1663-3Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIV, 868

  • Topics: Immunology, Biochemistry, general

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