Basic and Clinical Concepts of Lung Cancer

1. Front Matter

   Pages i-xv

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2. Lung Cancer in Developed and Developing Countries

   • Ken Stanley, Jan Stjernswärd

   Pages 1-14

3. The Impact of Prophylactic Methods in the Control of Lung Cancer in the U.S.A.

   • Joseph W. Cullen

   Pages 15-33

4. Advances in the Diagnosis of Lung Tumors

   • Bruce Mackay

   Pages 35-51

5. Observer Variability Studies of the WHO Classification of Lung Cancer

   • Ignatius T. M. Kung, Wah Kit Lam, Tai Hing Lam

   Pages 53-69

6. Immunohistochemistry of Lung Cancer: Cell differentiation and Growth Properties

   • Yukio Shimosato, Setsuo Hirohashi, Takashi Nakajima, Masayuki Noguchi

   Pages 71-87

7. Oncogenes and Human Lung Cancer

   • Sjoerd Rodenhuis

   Pages 89-106

8. Autocrine Growth Factors and Lung Cancer

   • James L. Mulshine, Ronald B. Natale, Ingalill Avis, Anthony M. Treston, Philip G. Kasprzyk, Yoichi Nakanishi et al.

   Pages 107-122

9. Cytogenetic Abnormalities in Lung Cancer

   • L. Campbell, J. Brown, O. M. Garson, G. Morstyn

   Pages 123-136

10. Clinical Correlation of Tumor Endocrine Markers in Lung Cancer

    • M. Teeling, P. McGing, P. Johnston, D. N. Carney

    Pages 137-149

11. Can Human Small-Cell Lung Cancer Cell Lines be Applied for Optimizing Chemotherapy?

    • Henrik Roed, Lars L. Vindeløv

    Pages 151-172

12. Interferons and Lung Cancer: Preclinical and Clinical Investigations

    • Ronald J. Fergusson, John F. Smyth

    Pages 173-182

13. Current Staging of Lung Cancer: An Overview of Current and Newer Approaches

    • Joseph Aisner, Nancy O. Whitley

    Pages 183-213

14. Prognostic Factors in Adenocarcinoma of the Lung

    • Jens Benn Sørensen

    Pages 215-243

15. Surgical Adjuvant Therapy of Non-Small-Cell Lung Cancer

    • E. Carmack Holmes

    Pages 245-258

16. High-dose Chemotherapy of Small-Cell Lung Cancer With and Without Bone Marrow Transplantation

    • J. P. Sculier, J. Klastersky

    Pages 259-274

17. CNS Therapy in Small-Cell Lung Cancer

    • Paul E. G. Kristjansen, Anders G. Pedersen

    Pages 275-299

18. Late Complications Associated with the Treatment of Small-Cell Lung Cancer

    • Ronald Feld

    Pages 301-323

19. Psychosocial Aspects of Patients with Lung Cancer in Controlled Clinical Trials

    • Stein Kaasa

    Pages 325-355

20. Back Matter

    Pages 357-368

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The last volume dealing with lung cancer in this series in Cancer Treatment and Research was published in 1986 and entitled Lung Cancer: Basic and Clinical Aspects. The present book continues the outline of the previous volume by presenting up-to-date information on lung cancer in critical reviews of new important basic and clinical concepts of lung cancer. The present volume has broadened the scope by also including chapters dealing with issues such as epidemiology, prophylaxis, and histopathology of lung cancer. The content of the book thus reflects the increasing awareness of a global disease that is more and more in focus, not only scientifically but also politically. The latter fact results increasingly in changes in health legisla­ tion, with prevention measures influencing everyday life. The great interest in the disease is natural, considering that more than one patient dies from lung cancer every minute globally. The first chapter is from the Cancer Unit, WHO, Geneva, and describes in detail the epidemiologic features of lung cancer, which is the second most frequent cancer in the world with 660,500 new cases annually; it will soon surpass stomach cancer as the leader. Thirty-one percent of the cases occur in developing countries, where the increase is especially dramatic.

• Staging
• adjuvant therapy
• bone marrow
• cancer
• cancer treatment
• carcinoma
• cell
• classification
• clinical trial
• histopathology
• interferon
• pathology
• prevention
• transplantation
• tumor
• surgical oncology

• The Finsen Institute, Rigshospitalet, Copenhagen, Denmark

  Heine H. Hansen

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