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The Heart in Diabetes

  • Book
  • © 1996

Overview

Editors:
  1. John C. Chatham

    1. Department of Radiology, Division of NMR Research, Johns Hopkins University School of Medicine, Baltimore, USA

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  2. John R. Forder

    1. Department of Radiology, Division of NMR Research, Johns Hopkins University School of Medicine, Baltimore, USA

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  3. John H. McNeill

    1. Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada

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Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 185)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  2. Clinical Manifestations of Diabetic Cardiomyopathy

    • Frederick S. Fein
    Pages 1-22

  3. Pathologic Alterations of the Heart in Diabetes Mellitus

    • Alain Borczuk, Stephen M. Factor
    Pages 23-40

  4. Alterations of Cardiac Function, Composition and Rhythm as a Consequence of Diabetes

    • Makilzhan Shanmugam, Louis Arroyo, Abbas Shehadeh, Timothy J. Regan
    Pages 41-65

  5. Therapeutic Interventions in the Diabetic Heart

    • John H. McNeill, Brian Rodrigues
    Pages 66-84

  6. Effect of Diabetes on Protein Synthesis in the Myocardium

    • David L. Geenen, Ashwani Malhotra
    Pages 85-99

  7. Remodelling of Subcellular Organelles During the Development of Diabetic Cardiomyopathy

    • Naranjan S. Dhalla, Leonard S. Golfman, Vijayan Elimban, Nobuakira Takeda
    Pages 100-142

  8. Ketone Body Metabolism in the Diabetic Heart

    • John R. Forder
    Pages 143-165

  9. Cardiac Glycogen Metabolism in Diabetes

    • Maren R. Laughlin
    Pages 166-188

  10. The Effect of Diabetes on Glucose Metabolism

    • John C. Chatham
    Pages 189-214

  11. Fatty Acid Metabolism in the Heart Following Diabetes

    • Gary D. Lopaschuk
    Pages 215-251

  12. Conclusion

    • John C. Chatham, John R. Forder, John H. McNeill
    Pages 252-259

  13. Back Matter

    Pages 260-267
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Keywords

About this book

Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life.
In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.

Editors and Affiliations

  • Department of Radiology, Division of NMR Research, Johns Hopkins University School of Medicine, Baltimore, USA

    John C. Chatham, John R. Forder

  • Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada

    John H. McNeill

Bibliographic Information

  • Book Title: The Heart in Diabetes

  • Editors: John C. Chatham, John R. Forder, John H. McNeill

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-1269-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1996

  • Hardcover ISBN: 978-0-7923-4052-2Published: 30 April 1996

  • Softcover ISBN: 978-1-4612-8541-0Published: 16 September 2011

  • eBook ISBN: 978-1-4613-1269-7Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: X, 268

  • Topics: Cardiology

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