Proliferative Vitreoretinopathy (PVR)

1. Front Matter

   Pages i-xx

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2. Proliferative Vitreoretinopathy (PVR): An Update

   1. Front Matter

      Pages 1-1

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   2. PVR: An Overview

      • Carl Claes, H. MacKenzie Freeman, Felipe I. Tolentino

      Pages 3-11

   3. Pathobiology of PVR

      • Bert M. Glaser

      Pages 12-21

   4. Anterior PVR Part I: Clinical Findings and Management

      • H. MacKenzie Freeman, Susan G. Elner, Felipe I. Tolentino, Charles L. Schepens, Victor M. Elner, Daniel M. Albert

      Pages 22-33

   5. Anterior PVR Part II: Clinicopathologic, Light Microscopic, and Ultrastructural Findings

      • Susan G. Elner, Victor M. Elner, Roberto Díaz-Rohena, H. MacKenzie Freeman, Felipe I. Tolentino, Daniel M. Albert

      Pages 34-45

   6. Management of Posterior PVR

      • Felipe I. Tolentino, H. MacKenzie Freeman

      Pages 46-53

   7. Management of Retinal Detachment with Moderate PVR

      • Stanley Chang, Harvey Lincoff, Emin Ozmert, Dov Weinberger, Peter J. G. Maris

      Pages 54-59

   8. Surgical Treatment of PVR

      • Anne M. Hanneken, Ronald G. Michels

      Pages 60-69

   9. Management of Severe (Grade D) PVR with Mechanical Fixation of the Retina

      • Brooks W. McCuen II, Eugene de Juan Jr., Robert Machemer

      Pages 70-75

   10. Treatment of Traumatic Traction Detachment in Eyes with PVR and Severe Damage to the Anterior Segment

       • Relja Živojnović, Diane A. E. Mertens, Ed Peperkamp, Sima Pavlović, Houdijn W. Beekhuis, Riel van Rij et al.

       Pages 76-80

   11. Pharmacologic Management of PVR

       • Mark S. Blumenkranz, Michael K. Hartzer

       Pages 81-87

   12. Intraocular Silicone Oil Versus Gas in the Management of PVR: A Multicenter Clinical Study

       • Walter H. Stern, John S. Lean, The Silicone Study Group

       Pages 88-96

3. A Discussion of Common Concerns

   1. Front Matter

      Pages 97-97

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   2. PVR: A Discussion of Common Concerns

      • Gary W. Abrams, Steven T. Charles, William H. Havener, Robert Machemer, Charles L. Schepens, Walter H. Stern

      Pages 97-102

4. PVR: Reports of Current Clinical and Research Studies

   1. Front Matter

      Pages 103-103

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   2. Photographic Documentation and Grading of PVR

      • Alexander R. Irvine, George F. Hilton, Lawrence I. Lonn, Ariah Schwartz, The Silicone Study Group

      Pages 105-109

   3. PVR: An Analysis of Factors in Retinal Detachments Using the PVR Classification

      • R. Sloan Wilson, David V. Poer, James H. Landers

      Pages 110-116

   4. PVR in Labrador Retrievers

      • Norman P. Blair

      Pages 117-123

   5. Stimulation of Retinal Pigment Epithelium (RPE) Proliferation and Migration of Macrophages

      • Sheldon M. Buzney, Salim A. Bishara

      Pages 124-129

The purpose of this book is to provide an update both on the present management of proliferative vitreoretinopathy (PVR) and on clinical and experimental research being done to control this disease. The book is divided into three parts. The first part deals with the current management of PVR. The Retina Society Classification of PVR is based in part on a gradation of severity from minimal to massive; therefore, this book attempts to correlate the management of PVR with its severity. The treatment of PVR of varying degrees of severity, from mild to the most severe form, is described by those authors with extensive experience with this spectrum of cases. Much progress has been made in the management of severe PVR as a result of vitreous injections, vitrectomy, periretinal membrane surgery, and retinal surgery. Authors in this book show that in mild and moderately severe PVR excellent results can be obtained with techniques that are less invasive and possibly less likely to stimulate further abnormal cellular proliferation. The new modalities for treatment of PVR are discussed by authors having extensive experience with them. The current status of pharmacological treatment and new concepts of the pathobiology of PVR are discussed. The second part of the book deals with questions frequently encountered in the management of PVR. These questions are answered by a panel of experts including Gary W. Abrams, Steven T. Charles, William H. Havener, Robert Machemer, Charles L. Schepens, and Walter H. Stern.

• biology
• classification
• documentation
• fixation
• macrophages
• management
• migration
• necrosis
• pathobiology
• pharmacology
• research
• retina
• surgery
• trauma
• treatment

• Harvard Medical School, Boston, USA

  H. MacKenzie Freeman, Felipe I. Tolentino

• Massachusetts Eye and Ear Infirmary, Boston, USA

  H. MacKenzie Freeman, Felipe I. Tolentino

• Ophthalmic Microsurgery Laboratory, Eye Research Institute of Retina Foundation, Boston, USA

  H. MacKenzie Freeman, Felipe I. Tolentino

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