Unusual DNA Structures

1. Front Matter

   Pages i-xvi

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2. Unusual DNA Structures and the Probes Used for their Detection

   • Robert D. Wells, Sorour Amirhaeri, John A. Blaho, David A. Collier, Jeffery C. Hanvey, Wang-Ting Hsieh et al.

   Pages 1-21

3. The Specificity of “Single Strand Specific Endonucleases”: Probes of phosphodiester conformation in double stranded nucleic acids. Left-Handed Polypurine/polypyrimidine structures. Long range transmission of conformational information in DNA.

   • David E. Pulleyblank, Mark Glover, Chuck Farah, David B. Haniford

   Pages 23-44

4. Chromatin Structure and DNA Structure at the hsp 26 Locus of Drosophila

   • S. C. R. Elgin, I. L. Cartwright, D. S. Gilmour, E. Siegfried, G. H. Thomas

   Pages 45-53

5. Cruciform Extrusion in Supercoiled DNA — Mechanisms and Contextual Influence

   • David M. J. Lilley, Karen M. Sullivan, Alastair I. H. Murchie, Judy C. Furlong

   Pages 55-72

6. Torsional Stress, Unusual DNA Structures, and Eukaryotic Gene Expression

   • Charles R. Cantor, Subhasis Bondopadhyay, Shamir K. Bramachari, Cho-Fat Hui, Michael McClelland, Randall Morse et al.

   Pages 73-89

7. Development of a Model for DNA Supercoiling

   • Stephen C. Harvey, Robert K.-Z Tan

   Pages 91-101

8. Cruciform Transitions Assayed Using a Psoralen Crosslinking Method: Applications to measurements of DNA torsional tension

   • David E. Pettijohn, Richard R. Sinden, Steven S. Broyles

   Pages 103-114

9. NMR-Distance Geometry Studies of Helical Errors and Sequence Dependent Conformations of DNA in Solution

   • Dinshaw J. Patel, Lawrence Shapiro, Dennis Hare

   Pages 115-161

10. Hyperreactivity of the B-Z Junctions Probed by Two Aromatic Chemical Carcinogens, 2-N,N-Acetoxyacetylaminofluorene and 3-N,N-Acetoxyacetyl-Amino-4,6-Dimethyldipyrido[1,2-a:3′,2′-d] Imidazole

    • Laurent Marrot, Annie Schwartz, Eric Hebert, Germain Saint-Ruf, Marc Leng

    Pages 163-171

11. Inherently Curved DNA and its Structural Elements

    • E. N. Trifonov, L. E. Ulanovsky

    Pages 173-187

12. DNA Flexibility Under Control: The Jumna Algorithm and its Application to BZ Junctions

    • Richard Lavery

    Pages 189-206

13. Base Sequence Effects in Curved and Rodlike DNA

    • Wilma K. Olson, A. R. Srinivasan, Rachid C. Maroun, Ramon Torres, William Clark

    Pages 207-224

14. Sequence-Dependent Curvature of DNA

    • Paul J. Hagerman

    Pages 225-236

15. Biophysical Principles of Specificity and Stability of Protein-DNA Interactions: Application to RNA Polymerase (Eσ70)-Promoter Interactions

    • M. Thomas Record Jr.

    Pages 237-251

16. Immunochemical Approaches to the Definition of Unusual Nucleic Acid Structures

    • B. David Stollar

    Pages 253-265

17. Molecular Mechanical Studies on the B → Z Energetics of DNA Sequences

    • Shashidhar N. Rao, Thomas Jovin, Peter A. Kollman

    Pages 267-285

18. Usual and Unusual DNA Structures: A Summing-Up

    • Richard E. Dickerson

    Pages 287-306

19. Back Matter

    Pages 307-311

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This book contains the papers which were presented at the First Gulf Shores Symposium on Unusual DNA Structures. The meeting was held April 6-8, 1987, in Gulf Shores, Alabama. Averitable explosion has taken place in recent years regarding our understanding of unusual DNA structures. This symposium was dedicated to enhancing our understanding of the biology and chemistry of these important structural features. The symposium was supported by funds provided by the Department of Biochemistry, University of Alabama at Birmingham, Schools of Medicine and Dentistry. We wish to express our app~eciationto Ms. Patti Guyton for her expert organizational skills and assistance in organizing the meeting and preparation of this book. Robert D. Wells and Stephen C. Harvey Department of Biochemistry Schools of Medicine and Dentistry University of Alabama at Birmingham Birmingham, Alabama 35294 VII VIII ;;C' Pete Dickie 1. Dave Wilson 20. 39. Paul Hagerman 58. Robert Shapiro 2. Wang-Ting Hsieh David Pettijohn 21. 40. Jacquelynn Larson 59. Angel Garcia 3. Hark Glover Hicaela Caserta 22. 41. Johanna Griffin 60. Richard Lavery 4. David Pulleyblank 23. Adam Jaworski 42. Jeremy Lee 61. Norma Wills 5. Robert Wells 24. Han Htun 43.

• Base
• DNA
• Purine
• Pyrimidine
• RNA
• biochemistry
• gene expression
• influence

• Department of Biochemistry, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, USA

  Robert D. Wells, Stephen C. Harvey

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