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Enzyme Dynamics and Regulation

  • Book
  • © 1988

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Editors:
  1. P. Boon Chock

    1. Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA

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  2. Charles Y. Huang

    1. Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA

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  3. C. L. Tsou

    1. Institute of Biophysics, Academia Sinica, Beijing, China

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  4. Jerry H. Wang

    1. Department of Medical Biochemistry, The University of Calgary, Calgary, Canada

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Table of contents (47 chapters)

  1. Front Matter

    Pages i-xxi
    Download chapter PDF

  2. Enzyme Kinetics and Mechanisms

    1. Mechanistic Studies on DNA Polymerase I

      • V. Mizrahi, P. A. Benkovic, R. D. Kuchta, M. C. Young, K. A. Johnson, S. J. Benkovic
      Pages 1-5

    2. Assembly and Catalytic Functions of the Subunits of Succinyl Coenzyme A Synthetase

      • William A. Bridger, William T. Wolodko, Susan P. Williams
      Pages 6-16

    3. Fatty Acid Synthetase of Chicken Liver: A Novel Active-Site Structure for Condensation Comprised of SH Groups from a Cysteine Residue and an Oscillating Phosphopantetheine Swinging Arm on Adjacent Subunits

      • Robert Y. Hsu
      Pages 17-27

    4. Regulatory Properties of Glucokinase

      • Kenneth E. Neet, Peter S. Tippett, Robert P. Keenan
      Pages 28-39

    5. Mechanism of Activation of Calmodulin-Dependent Phosphatase by Divalent Metal Ions

      • Charles Y. Huang, Marina Lanciotti, Aile Zhang
      Pages 40-47

    6. Studies on the Mechanism and Molecular Mode of Regulation of Fructose-1,6-bisphosphatase

      • Julie E. Scheffler, Herbert J. Fromm
      Pages 48-54

    7. Phosphorylation and dAMP Inhibition of Snake Muscle Fructose-1,6-bisphosphatase

      • Gen-Jun Xu, Guo-Fu Hu, Fu-Kun Zhao, Qi-Chang Xia
      Pages 55-61

    8. Identification and Characterization of Intermediates in the Mechanism of Enzyme Action

      • Bert L. Vallee, David S. Auld
      Pages 62-70

    9. Conformational Dynamics in RNA—Protein Interactions: Immobilization of the Functional Domains in tRNAfMet and Methionyl-tRNA Synthetase

      • David C. H. Yang, Blair Q. Ferguson
      Pages 71-76

    10. Structural and Kinetic Studies of Escherichia coli Glutamine Synthetase

      • J. J. Villafranca, C. D. Eads, R. LoBrutto, F. C. Wedler, J. Colanduoni
      Pages 77-83

    11. Cu,Zn Superoxide Dismutase: A Case of Metalloenzyme Catalysis in Which the Protein Moiety Plays a Major Role

      • Adelio Rigo, Lilia Calabrese, Giuseppe Rotilio
      Pages 84-91

  3. Regulatory Enzymes

    1. Dynamic Participation of Protein Domains in Catalysis by 2-Oxo Acid Dehydrogenase Multienzyme Complexes

      • Richard N. Perham
      Pages 92-101

    2. Membrane-Bound GTP-Transducin Efficiently Activates Retinal cGMP Phosphodiesterase

      • Theodore G. Wensel, Lubert Stryer
      Pages 102-112

    3. Signal Transduction in the β-Adrenoceptor-Dependent Adenylate Cyclase

      • Alexander Levitzki
      Pages 113-120

    4. Acetyl-CoA Carboxylase: Correlation of Phosphorylation State with Allosteric Properties and Physiological State

      • Haris Jamil, Neil B. Madsen
      Pages 121-127

    5. Role of Cyclic Cascades in Metabolic Regulation

      • P. Boon Chock, Stewart R. Jurgensen, Sue Goo Rhee, Earl R. Stadtman, Jackie R. Vandenheede
      Pages 128-135

    6. Regulation of Glutamine Synthetase Activity and Its Biosynthesis in Escherichia coli: Mediation by Three Cycles of Covalent Modification

      • Sue Goo Rhee, Wong Gi Bang, Ja Hyun Koo, Kyung Hee Min, Sang Chul Park
      Pages 136-145

    7. Regulation of ATP, Mg-Dependent Protein Phosphatases

      • Jackie R. Vandenheede, Carline Vanden Abeele, Wilfried Merlevede
      Pages 146-154

    8. Molecular Mechanisms of Allosteric Regulation in Aspartate Transcarbamylase

      • Guy Hervé
      Pages 155-161
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Keywords

About this book

Recent developments in concepts and techniques have brought enzyme research to a changing yet exciting stage. Enzymes have served as indispensable tools in the phenomenal rise of molecular biology, and the resultant biotechnology thrusts enzymes to new heights and territories. This volume, the proceedings of a recent symposium on the Dynamics of Soluble and Immobilized Enzyme Systems, provides a current overview of the field to help scientists utilize long-established and newly acquired information.

Editors and Affiliations

  • Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA

    P. Boon Chock, Charles Y. Huang

  • Institute of Biophysics, Academia Sinica, Beijing, China

    C. L. Tsou

  • Department of Medical Biochemistry, The University of Calgary, Calgary, Canada

    Jerry H. Wang

Bibliographic Information

  • Book Title: Enzyme Dynamics and Regulation

  • Editors: P. Boon Chock, Charles Y. Huang, C. L. Tsou, Jerry H. Wang

  • DOI: https://doi.org/10.1007/978-1-4612-3744-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1988

  • Softcover ISBN: 978-1-4612-8330-0Published: 13 October 2011

  • eBook ISBN: 978-1-4612-3744-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXI, 421

  • Topics: Biochemistry, general, Cell Biology, Biotechnology

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