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Cell Biology of Extracellular Matrix

  • Book
  • © 1981

Overview

Editors:
  1. Elizabeth D. Hay

    1. Department of Anatomy, Harvard Medical School, Boston, USA

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Introductory Remarks

    1. Introductory Remarks

      • Elizabeth D. Hay
      Pages 1-4

  3. What is Extracellular Matrix?

    1. Collagen

      • T. F. Linsenmayer
      Pages 5-37

    2. Proteoglycans

      • Vincent C. Hascall, Gretchen K. Hascall
      Pages 39-63

    3. Elastin

      • Carl Franzblau, Barbara Faris
      Pages 65-93

    4. Fibronectin and Other Structural Proteins

      • Kenneth M. Yamada
      Pages 95-114

  4. How Do Cells Produce the Matrix?

    1. Proteoglycan Biosynthesis

      • Albert Dorfman
      Pages 115-138

    2. Collagen Biosynthesis

      • Bjorn Reino Olsen
      Pages 139-177

    3. Matrix Assembly

      • Robert L. Trelstad, Frederick H. Silver
      Pages 179-215

    4. An Essay on Biological Degradation of Collagen

      • Jerome Gross
      Pages 217-258

  5. What Does Matrix Do for Cells?

    1. Glycosaminoglycans in Morphogenesis

      • Bryan P. Toole
      Pages 259-294

    2. Fibronectin and Its Relation to Cellular Structure and Behavior

      • Richard O. Hynes
      Pages 295-334

    3. The Glomerular Basement Membrane

      • Marilyn Gist Farquhar
      Pages 335-378

    4. Collagen and Embryonic Development

      • Elizabeth D. Hay
      Pages 379-409

  6. Back Matter

    Pages 411-417
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Keywords

About this book

At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto­ plasm. The idea of this book is to present the extracellular matrix to cell biolo­ gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro­ graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.

Editors and Affiliations

  • Department of Anatomy, Harvard Medical School, Boston, USA

    Elizabeth D. Hay

Bibliographic Information

  • Book Title: Cell Biology of Extracellular Matrix

  • Editors: Elizabeth D. Hay

  • DOI: https://doi.org/10.1007/978-1-4613-0881-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1981

  • Softcover ISBN: 978-1-4612-8226-6Published: 08 October 2011

  • eBook ISBN: 978-1-4613-0881-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVII, 417

  • Number of Illustrations: 147 b/w illustrations, 1 illustrations in colour

  • Topics: Cell Biology, Science, Humanities and Social Sciences, multidisciplinary

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