Molecular Mechanisms of Microbial Adhesion

1. Front Matter

   Pages i-xviii

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2. Bacterial Adherence

   • Edwin H. Beachey

   Pages 1-4

3. Heterogeneity of Renal Glycoconjugates: Biochemical and Bacteriological Aspects

   • H. Holthofer, R. Virkola, B. Westerlund, T. Vartio, P. Kuusela, T. K. Korhonen

   Pages 5-22

4. TCP Pilus Expression and Biogenesis by Classical and El Tor Biotypes of Vibrio Cholerae 01

   • Carolyn E. Shaw, Kenneth M. Peterson, Daxi Sun, John J. Mekalanos, Ronald K. Taylor

   Pages 23-35

5. Isolation of the Pre-Assembled Gal α(1–4)Gal-Specific Pilus-Associated Adhesin from the Periplasm in Uropathogenic Escherichia Coli

   • Scott J. Hultgren, Frederik Lindberg, Göran Magnusson, Jan M. Tennent, Staffan Normark

   Pages 36-43

6. Interaction of Isogenic Pilus+ and Pilus− Variants of Gonococci with a Human Epithelial Cell Line

   • Michael Koomey

   Pages 44-51

7. Molecular Approaches to Characterization of Mycoplasmal Adhesins

   • Shmuel Razin, David Yogev

   Pages 52-76

8. Current Experience from the Interaction of Bacteria with Glycosphingolipids

   • Karl-Anders Karlsson

   Pages 77-96

9. Molecular Basis for Fibronectin-Mediated Adherence in the Syphilis Spirochetes

   • Victor V. Tryon, Bradley C. Stiles, John F. Alderete, Joel B. Baseman

   Pages 97-106

10. A Fibronectin Binding Protein from Staphylococcus Aureus and its Role in Bacterial Adherence

    • Magnus Höök, Giuseppe Raucci, Rampyari Raja, Christer Signäs, Klas Jönsson, Per-Eric Lindgren et al.

    Pages 107-117

11. Evolutionary Conservation of the Binding Site of a Laminin Receptor as Determined by Monoclonal Antibodies and Hydropathically Complementary Peptides

    • C. R. W. Carneiro, G. F. A. Mota, J. Sabaga, M. Marquezini, P. Potocnjak, R. R. Brentani

    Pages 118-127

12. Effect of Mucosal Antibodies to M Protein on Colonization by Group A Streptococci

    • Vincent A. Fischetti, Debra Bessen

    Pages 128-142

13. Adsorbed Salivary Proline-Rich Proteins as Bacterial Receptors on Apatitic Surfaces

    • R. J. Gibbons, D. I. Hay

    Pages 143-163

14. Bacterial and Host Cell Receptors for the Actinomyces spp. Fimbrial Lectin

    • John O. Cisar, Michael J. Brennan, Ann L. Sandberg

    Pages 164-170

15. Adhesins of Bacteroides Loescheii

    • Jack London, Ervin I. Weiss, Paul E. Kolenbrander

    Pages 171-176

16. The Race for the Surface: Microbes, Tissue Cells, and Biomaterials

    • Anthony G. Gristina, Paul T. Naylor, Quentin Myrvik

    Pages 177-211

17. Bacterial Adherence as Target for Preventing Infection

    • P. Helena Mäkelä

    Pages 212-221

18. Back Matter

    Pages 223-226

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It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists. The fact that bacterial attachment to the host tissue is a prerequisite for infection understandably led to the hope that infections could be prevented by blocking the adhesion of pathogenic bacteria. Progress in this field has been so rapid that it has become difficult to keep up with recent developments. This book contains the proceedings of the symposium on the Molecular Mechanisms of Microbial Adhesion, May 6-8, 1988. Both the symposium and this book were intended as an up-to-date review of the most recent findings concerning the adhesion of medically important bacteria. In addition, this book contains critical and provocative overviews of the past, present and future of this field.

• Monoclonal Antibodies
• biochemistry
• escherichia coli
• microbe
• molecular mechanisms
• protein

• Department of Biochemistry, University of Alabama at Birmingham, Birmingham, USA

  Lech Switalski, Magnus Höök

• University of Tennessee, Memphis, USA

  Edwin Beachey

• Veterans Administration Medical Center, Memphis, USA

  Edwin Beachey

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