Overview
- Editors:
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Akitane Mori
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Okayama University Medical School, Okayama, Japan
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Burton D. Cohen
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The Bronx Lebanon Hospital Center, Bronx, USA
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Hikaru Koide
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Juntendo University School of Medicine, Tokyo, Japan
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Table of contents (41 chapters)
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Analytical Method for Guanidino Compounds and New Guanidino Compounds
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- Moto-o Nakajima, Kazuo Nakamura, Yoshio Shirokane, Yoshihei Hirasawa
Pages 3-11
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- Katsuo Haruki, Shuichi Hatakeyama, Masayoshi Hirata, Hiroaki Muramoto, Yohei Tofuku, Ryoyu Takeda
Pages 13-14
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- Shigeru Matsuzaki, Koei Ramana, Kimiyasu Isobe
Pages 15-21
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- Yvonne Robin, Yvonne Guillou
Pages 23-31
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Metabolism of Guanidino Compounds
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- Ijaz A. Qureshi, Bart Marescau, Maurice Levy, Peter P. De Deyn, Jacques Letarte, Armand Lowenthal
Pages 45-51
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- Yoko Watanabe, Isao Yokoi, Akitane Mori
Pages 53-60
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- Myron D. Gross, Alexander M. Simon, Richard J. Jenny, Ernest D. Gray, Denise M. McGuire, John F. Van Pilsum
Pages 61-69
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- Kazumasa Aoyagi, Sohji Nagase, Masako Sakamoto, Mistuharu Narita, Shizuo Tojo
Pages 71-77
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- Kazumasa Aoyagi, Sohji Nagase, Masako Sakamoto, Mitsuharu Narita, Shizuo Tojo
Pages 79-85
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- Masako Sakamoto, Kazumasa Aoyagi, Sohji Nagase, Shoji Ohba, Mitsuhiro Miyazaki, Mitsuharu Narita et al.
Pages 87-95
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- Midori Hiramatsu, Rei Edamatsu, Masahiro Kohno, Akitane Mori
Pages 97-105
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Physiological, Pharmacological and Toxicological Aspects of Guanidino Compounds
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Front Matter
Pages 107-107
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- Katsuya Nagai, Akiko Hashida, Hachiro Nakagawa
Pages 115-122
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- Kazumasa Aoyagi, Sohji Nagase, Masako Sakamoto, Mitsuharu Narita, Shizuo Tojo
Pages 123-128
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- Michio Kitaura, Yoji Ochiai, Seiji Sugimoto, Koji Kabutan, Yoshinori Kosogabe, Chiaki Tsuji et al.
Pages 129-134
About this book
Guanidine is named for its similarity to the purine guanine which, in turn, is named for its principal source guano, which comes from the Inca word, huano, for dung. Guanidine, therefore, translates into dung-like, which is hardly a genteel way to introduce a subject. On the other hand, texts are seldom inspirational, "frequently crude and rarely literary and should be judged on how successfully they assemble, organize and present current data. I am impressed that the material which fol]ows goes a long way toward successfully achieving those goals. Tue International Guanidine Society is a synthesis of three groups of investigators: biologists studying guanidines as phosphagens, neurologists interested in guanidines as convulsants and nephrologists involved with guanidines as toxins. As a member of the latter group. I am gratified by the considerable progress this book represents. To begin with. there now appears to be a common theme which unifies current speculation concerning the metabolic origin of the guanidines in uremia. At the First International Congress in 1983, evidence was presented which supported the theory that certain guanidines were products of the mixed function oxidation of urea. This year's meeting brings together overwhelming data showing that methyl guanidine is an effect of active oxygen reacting with creatinine. An idolatry, worshipped throughout biochemistry, that urea and creatinine are inert byproducts of protein metabolism, is shown to have feet of clay.
Editors and Affiliations
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Okayama University Medical School, Okayama, Japan
Akitane Mori
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The Bronx Lebanon Hospital Center, Bronx, USA
Burton D. Cohen
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Juntendo University School of Medicine, Tokyo, Japan
Hikaru Koide
