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Purines in Cellular Signaling

Targets for New Drugs

  • Conference proceedings
  • © 1990

Overview

Editors:
  1. Kenneth A. Jacobson

    1. Laboratory of Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

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  2. John W. Daly

    1. Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

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  3. Vincent Manganiello

    1. Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, NIH, Bethesda, USA

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Table of contents (54 papers)

  1. Front Matter

    Pages i-xv
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  2. Adenosine Receptors and Effector Systems

    1. Front Matter

      Pages 1-1
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    2. Adenosine Agonists and Antagonists

      • J. W. Daly
      Pages 3-12

    3. Intracellular and Extracellular Metabolism of Adenosine and Adenine Nucleotides

      • D. Pearson, L. L. Slakey
      Pages 13-19

    4. Adenosine Deaminase and Adenosine Transport Systems in the CNS

      • J. D. Geiger, R. A. Padua, J. I. Nagy
      Pages 20-25

    5. Transport Systems for Adenosine in Mammalian Cell Membranes

      • A. S. Clanachan, F. E. Parkinson
      Pages 26-32

    6. Formation of Adenosine in the Heart from Extracellular Adenine Nucleotides

      • J. Schrader, M. M. Borst, M. Kelm, B. Bading, K. F. Bürrig
      Pages 33-40

    7. Central Nervous System Effects of Adenosine

      • J. W. Phillis
      Pages 41-47

    8. Adenosine Receptor Sub-types in Isolated Tissues: Antagonist Studies

      • M. G. Collis
      Pages 48-53

    9. Molecular Probes for Adenosine Receptors

      • K. A. Jacobson
      Pages 54-64

    10. Purification of A1 Adenosine Receptor of Rat Brain Membranes by Affinity Chromatography

      • H. Nakata
      Pages 65-68

    11. Characteristics of A1 Adenosine Receptors and Guanine Nucleotide Binding Proteins Co-Purified from Bovine Brain

      • J. Linden, R. Munshi, M. L. Arroyo, A. Patel
      Pages 69-72

    12. Antagonist Radioligand Binding to Solubilized Porcine Atrial A1 Adenosine Receptors

      • M. Leid, P. H. Franklin, T. F. Murray
      Pages 73-77

    13. Isolation of an Adenosine Binding Protein Which Has Properties Expected of the A1 Adenosine Receptor

      • K. Ravid, J. M. Lowenstein
      Pages 78-81

    14. Identification of the A2 Adenosine Receptor Binding Subunit by Photoaffinity Crosslinking

      • W. W. Barrington, K. A. Jacobson, A. J. Hutchison, M. Williams, G. L. Stiles
      Pages 82-85

    15. Human Placental Adenosine A2-Like Binding Sites Properties and Homology with Mammalian and Avian Stress Proteins

      • K. A. Hutchison, B. Nevins, F. Perini, I. H. Fox
      Pages 86-89

    16. Cardiac Interstitial Fluid Adenosine in Normoxia and Hypoxia

      • R. M. Berne
      Pages 90-95

    17. Rationale for the Use of Adenosine in the Diagnosis and Treatment of Cardiac Arrhythmias

      • L. Belardinelli, A. Pelleg
      Pages 95-99

    18. The Central Adenosine System as a Therapeutic Target in Stroke

      • P. J. Marangos, D. Von Lubitz, L. P. Miller, J. L. Daval, J. Deckert
      Pages 100-107

    19. Adenosine-Mediated Vasoconstriction in the Skin Microcirculation

      • K. G. Proctor, I. Stojanov
      Pages 108-113
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Keywords

Editors and Affiliations

  • Laboratory of Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

    Kenneth A. Jacobson

  • Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

    John W. Daly

  • Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, NIH, Bethesda, USA

    Vincent Manganiello

Bibliographic Information

  • Book Title: Purines in Cellular Signaling

  • Book Subtitle: Targets for New Drugs

  • Editors: Kenneth A. Jacobson, John W. Daly, Vincent Manganiello

  • DOI: https://doi.org/10.1007/978-1-4612-3400-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1990

  • Softcover ISBN: 978-1-4612-7996-9Published: 26 September 2011

  • eBook ISBN: 978-1-4612-3400-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XV, 448

  • Topics: Medicine/Public Health, general, Biochemistry, general, Pharmacy, Pharmacology/Toxicology

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