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Endocrine Function and Aging

  • Book
  • © 1990

Overview

Editors:
  1. H. James Armbrecht

    1. Geriatric Research, Education, and Clinical Center, Veterans Administration Medical Center, St. Louis, USA
      Department of Internal Medicine, St. Louis University School of Medicine, St. Louis, USA
      Department of Biochemistry, St. Louis University School of Medicine, St. Louis, USA

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  2. Rodney M. Coe

    1. Geriatric Research, Education, and Clinical Center, Veterans Administration Medical Center, St. Louis, USA
      Department of Internal Medicine, St. Louis University School of Medicine, St. Louis, USA
      Department of Community Medicine, St. Louis University School of Medicine, St. Louis, USA

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  3. Nirandon Wongsurawat

    1. Geriatric Research, Education, and Clinical Center, Veterans Administration Medical Center, St. Louis, USA
      Department of Internal Medicine, St. Louis University School of Medicine, St. Louis, USA

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xxi
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  2. Age-Related Changes in Hormone Secretion and Action

    1. Front Matter

      Pages N2-N2
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    2. Alterations in Hypothalamic-Pituitary Function with Age

      • Joseph Meites
      Pages 1-12

    3. Alterations in Hormone Syntheses and Secretion with Age

      • F. J. Mangiacapra, James R. Florini
      Pages 13-25

    4. Changes in Hormone Action with Age: Altered Calcium Mobilization and/or Responsiveness Impairs Signal Transduction

      • George S. Roth
      Pages 26-34

  3. Regulation of Carbohydrate Metabolism (Diabetes)

    1. Front Matter

      Pages N3-N3
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    2. Pathogenesis and Management of Non-Insulin-Dependent Diabetes Mellitus

      • William C. Duckworth
      Pages 35-47

    3. Glucose Tolerance, Insulin Sensitivity, and Age

      • Dariush Elahi, Barbara Clark, Reubin Andres
      Pages 48-63

  4. Maintenance of Bone Structure (Osteoporosis)

    1. Front Matter

      Pages 65-65
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    2. Diagnosis and Treatment of Osteoporosis

      • William A. Peck
      Pages 67-78

    3. Changes in the Production and Action of 1,25-Dihydroxyvitamin D and Parathyroid Hormone with Age

      • H. James Armbrecht, Nirandon Wongsurawat
      Pages 79-87

    4. Effect of Age on PTH-Stimulated Sodium Calcium Exchange Activity: Alteration at Cellular and Molecular Levels

      • C. T. Liang, H. Hanai, L. Cheng, J. Barnes, B. Sacktor
      Pages 88-98

  5. Maintenance of Reproductive Function (Impotence)

    1. Front Matter

      Pages N5-N5
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    2. Testicular Function in the Aging Male

      • John E. Morley, Fran E. Kaiser
      Pages 99-114

    3. Management of Female Menopause

      • Ronald C. Strickler
      Pages 115-135

    4. Psychological Aspects of Sexual Dysfunction in the Elderly

      • Mark L. Elliott
      Pages 136-146

  6. Regulation of Blood Pressure (Hypertension)

    1. Front Matter

      Pages N7-N7
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    2. Treatment of Hypertension in the Elderly

      • Michael L. Tuck
      Pages 147-160

    3. Macronutrients in the Diet: A Possible Association with Age-Related Hypertension

      • Harry G. Preuss, Mohmed Zein, Jorge L. Areas, Gao Chun Yun
      Pages 161-174

  7. Adaptation to Stress

    1. Front Matter

      Pages N9-N9
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Keywords

About this book

One of the hallmarks of aging is the decreased capacity to adapt to changes in the environment. In a constant, controlled environment, it is often difficult to distin­ guish the functioning of the young organism from that of the old. However, when stresses are applied-temperature stresses, dietary stresses, infection, emotional stresses-the differences are more apparent. Frequently, the response ofthe old is delayed and may never reach the same mag'nitude as the young. These responses, in most cases, are mediated by the neuroendocrine system, which communicates via hormones, neurotransmitters, and related substances. Thus, it is important to understand the age-related changes that take place in the secretion and act ion of these substances and how these changes relate to the well-being of the whole organism. Indeed, the "neuroendocrine theory of aging" proposes that almost all of the characteristics of aging can be accounted for by dysfunction of the neuroendocrine system. A book on endocrine function and aging is particularly relevant at this time. With the advent of the techniques of molecular biology, there has bee~ an explo­ sion of knowledge concerning hormone secretion and action. Hormones, pro­ hormones, hormone receptors, and "second messenger" mediators rapidly are being cloned and sequenced. Such knowledge gives us important insights into the molecular workings of these substances as well as into the genetic hasis of endo­ crine dysfunction. These new tools are now being applied to the problem of age­ related changes in endocrine function.

Editors and Affiliations

  • Geriatric Research, Education, and Clinical Center, Veterans Administration Medical Center, St. Louis, USA

    H. James Armbrecht, Rodney M. Coe, Nirandon Wongsurawat

  • Department of Internal Medicine, St. Louis University School of Medicine, St. Louis, USA

    H. James Armbrecht, Rodney M. Coe, Nirandon Wongsurawat

  • Department of Biochemistry, St. Louis University School of Medicine, St. Louis, USA

    H. James Armbrecht

  • Department of Community Medicine, St. Louis University School of Medicine, St. Louis, USA

    Rodney M. Coe

Bibliographic Information

  • Book Title: Endocrine Function and Aging

  • Editors: H. James Armbrecht, Rodney M. Coe, Nirandon Wongsurawat

  • DOI: https://doi.org/10.1007/978-1-4612-3240-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1990

  • Softcover ISBN: 978-1-4612-7930-3Published: 26 September 2011

  • eBook ISBN: 978-1-4612-3240-7Published: 21 December 2013

  • Edition Number: 1

  • Number of Pages: XXIII, 236

  • Number of Illustrations: 35 b/w illustrations

  • Topics: Endocrinology, Metabolic Diseases, Biochemistry, general

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