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  • Conference proceedings
  • © 1992

Modes of Action of GnRH and GnRH Analogs

Editors:

  1. William F. Crowley

    1. Reproductive Endocrine Unit Department of Medicine, Massachusetts General Hospital, Boston, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. P. Michael Conn

    1. Department of Pharmacology, University of Iowa College of Medicine, Iowa City, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Serono Symposia USA (SERONOSYMP)

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Table of contents (23 papers)

  1. Front Matter

    Pages i-xviii
    PDF

  2. Overview of GnRH Secretion and Mechanism of Action

    1. Front Matter

      Pages 1-1
      PDF

    2. Critical Determinants of GnRH-Gonadotrope Interactions in the Human

      • Randall W. Whitcomb, William F. Crowley Jr.
      Pages 3-25

    3. Gonadotropin Releasing Hormone and Its Actions

      • Tim D. Braden, P. Michael Conn
      Pages 26-54

    4. Regulation of Gonadotropin Gene Expression by Gonadotropin Releasing Hormone

      • John C. Marshall, Alan C. Dalkin, Daniel J. Haisenleder
      Pages 55-66

  3. Molecular and Developmental Control of GnRH Expression

    1. Front Matter

      Pages 67-67
      PDF

    2. Molecular Studies of GnRH, Part I

      • C. T. Bond, R. Seal, R. Simerly, J. P. Adelman
      Pages 69-78

    3. Molecular Studies of GnRH, Part II

      • C. T. Bond, R. Fernald, R. Francis, J. P. Adelman
      Pages 79-84

    4. Characterization, Expression, and Estradiol Regulation of the Human GnRH Gene

      • Sally Radovick, Fredric E. Wondisford, Susan Wray, Christine Ticknor, Yuko Nakayama, Gordon B. Cutler Jr. et al.
      Pages 85-105

    5. Control of Rat Gonadotropin Releasing Hormone Promoter Activity in Placental Cells

      • Margaret E. Wierman, Wei Sun, Chun Wang, David F. Gordon, William W. Wood
      Pages 106-115

    6. Cellular and Molecular Aspects of LHRH Secretion and Bioactivity

      • Andrés Negro-Vilar, William Wetsel, Marcelo Valença, Istvan Merchenthaler, Francisco López, Zsolt Liposits et al.
      Pages 116-130

    8. Functional GnRH Neuronal Transplants in the Hypogonadal Mouse

      • Marie J. Gibson, Youichi Saitoh, Gregory M. Miller, Ann-Judith Silverman
      Pages 144-157

  4. GnRH Physiology: Animal Models

    1. Front Matter

      Pages 159-159
      PDF

    2. GnRH Subgroups: A Microarchitecture

      • J. C. King, B. S. Rubin
      Pages 161-178

    5. Gonadal Feedback Regulation of LHRH Release and Actions in the Rat

      • Janice H. Urban, John M. Meredith, Angela C. Bauer-Dantoin, Frank J. Strobl, Jon E. Levine
      Pages 211-222

    6. Gonadotropin Releasing Hormone Gene Expression During the Rat Reproductive Cycle

      • Ok-Kyong Park, Sajiv Gugneja, Kelly E. Mayo
      Pages 223-240

    7. The Preovulatory Surge of Gonadotropin Releasing Hormone

      • Fred J. Karsch, Suzanne M. Moenter, Alain Caraty
      Pages 241-255
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About this book

Since the awarding of the Nobel Prize to Drs. Guillemin and Schally iJ) 1971 for isolation and chemical characterization of gonadotropin releasing hormone, we have experienced a remarkable period of growth of interest in this hormone. The last 20 years have been characterized by a swift translation of basic science discovery into clinical utility. Approval of GnRH and its analogs for treatment of prostate cancer, endometriosis, of ovulation indicate the range and precocious puberty and for induction of these agents. of usefulness In order to bring together the leaders in the basic and clinical science of GnRH, a conference was organized on "Modes of Action of GnRH and GnRH Analogs" and held in Scottsdale, Arizona, February 26 to March 2, 1991. The presentations, given as chapters in this volume, show both the advances in the body of information in this discipline and the efforts underway to reduce basic science to clinical practice. The audience was a combination of representatives from universities, government, industry, and physicians in practice. The lively discussions and insightful questions indicated the interest in the topics discussed and frequently served to catalyze planned interactions of the meeting participants. The organizers are grateful to the speakers and poster presenters for their contributions and for the timely preparations of the manuscripts included in the present volume. We are also thankful to the staff of Serono Symposia, USA, for the organizational skills and support that allowed the meeting organizers to focus on the science and medicine presented.
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Keywords

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Editors and Affiliations

  • Reproductive Endocrine Unit Department of Medicine, Massachusetts General Hospital, Boston, USA

    William F. Crowley

  • Department of Pharmacology, University of Iowa College of Medicine, Iowa City, USA

    P. Michael Conn

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Bibliographic Information

  • Book Title: Modes of Action of GnRH and GnRH Analogs

  • Editors: William F. Crowley, P. Michael Conn

  • Series Title: Serono Symposia USA

  • DOI: https://doi.org/10.1007/978-1-4612-2916-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York, Inc. 1992

  • Softcover ISBN: 978-1-4612-7718-7Published: 28 September 2011

  • eBook ISBN: 978-1-4612-2916-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 378

  • Topics: Gynecology, Human Physiology

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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