Overview
- Editors:
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Michael J. Soares
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Department of Physiology, University of Kansas Medical Center, Kansas City, USA
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Frank Talamantes
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Department of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, USA
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Stuart Handwerger
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Division of Endocrinology, Children’s Hospital Medical Center, Cincinnati, USA
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Table of contents (20 papers)
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All in the Family: The Growth Hormone, Prolactin, and Placental Lactogen Triad
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Trophoblast Development and Organization
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- Barry F. King, Thomas N. Blankenship
Pages 13-30
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- F. B. P. Wooding, G. Morgan
Pages 31-44
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- Michael J. Soares, Teresa N. Faria, Gary P. Hamlin, Xing-Jian Lu, Santanu Deb
Pages 45-67
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Trophoblast-Uterine Interactions
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- S. K. Dey, B. C. Paria, S. K. Das, G. K. Andrews
Pages 71-91
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- John D. Aplin, Ljiljana Vićovac, Abdul Sattar
Pages 92-108
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- Yan Zhou, Caroline H. Damsky, King Chiu, James M. Roberts, Susan J. Fisher
Pages 109-122
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- Mats E. GĂĄfvels, George Coukos, Christos Coutifaris, Dudley K. Strickland, Jerome F. Strauss III
Pages 123-133
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- Stuart Handwerger, Randall G. Richards, Susan E. Myers
Pages 134-150
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- Y. W. Loke, Ashley King, Gill Chumbley
Pages 151-159
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Biology of Trophoblast Cell Signaling Systems
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Front Matter
Pages 161-161
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- Frank Talamantes, Masaaki Yamaguchi, Gudmundur Thordarson, Jonathan Southard, Linda Ogren
Pages 163-168
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- Mary Lynn Duckworth, May C. Robertson, Ingo C. Schroedter, Claude Szpirer, Henry G. Friesen
Pages 169-190
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- Linda A. Schuler, Patricia Scott, Mark A. Kessler
Pages 191-205
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- R. Michael Roberts, Douglas W. Leaman, Jose Juan Hernandez-Ledezma, Neal C. Cosby
Pages 206-221
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- N. E. Cooke, B. K. Jones, M. Urbanek, A. Misra-Press, A. K. Lee, J. E. Russell et al.
Pages 222-239
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Regulation of Trophoblast Gene Expression
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Front Matter
Pages 241-241
About this book
Trophoblast cells coordinate the activities of maternal and embryonic tissues by secreting hormones, cytokines, and various growth factors that selectively and specifically gain access to maternal and embryonic compartments. Abnormalities associated with trophoblast cell growth, differentiation, or function result in impaired embryonic development. Understanding the complexities of the trophoblast cell signaling system was the focus of the Serono Symposia, USA conference entitled Tropho blast Cells: Pathways for Maternal-Embryonic Communication, held August 6-9, 1992, in Las Vegas, Nevada. The conference was designed to provide a forum for morphologists, cell biologists, endocrinologists, and molecular biologists and for scientists investigating primate, ru minant, and rodent trophoblast biology. An important outcome of the conference was the communication achieved between basic scientists and clinicians. This volume represents the contributions of the invited symposium speakers. The opening keynote address of the conference was entitled "Chorio carcinoma and the Embryo" and was presented by G. Barry Pierce, M. D. , Centennial Distinguished Research Professor of the University of Colorado School of Medicine. The address is not represented in this volume, but deserves a special comment. Dr. Pierce's scientific con tributions have significantly influenced our understanding of trophoblast cells. Dr. Pierce, together with Dr. A. Rees Midgley, identified the origin of syncytial trophoblast cells of the primate placenta and discovered that these cells were responsible for the production of chorionic gonadotropin (J Exp Med 1962;115:289-94; Am J Pathol 1963;43:929-43; and Science 1963;141:349-50).
Editors and Affiliations
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Department of Physiology, University of Kansas Medical Center, Kansas City, USA
Michael J. Soares
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Department of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, USA
Frank Talamantes
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Division of Endocrinology, Children’s Hospital Medical Center, Cincinnati, USA
Stuart Handwerger